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Volumn 5, Issue 1, 2003, Pages 15-18

Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities

Author keywords

cGMP; Icariin; PDE5; Penile erection

Indexed keywords

CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; ICARIIN; PAPAVERINE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; SILDENAFIL; TRITIUM;

EID: 0037360716     PISSN: 1008682X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (88)

References (26)
  • 1
    • 0034660235 scopus 로고    scopus 로고
    • Erectile Dysfunction
    • Lue T F. Erectile Dysfunction. N Engl J Med 2000; 342: 1802-13.
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1802-1813
    • Lue, T.F.1
  • 3
    • 0036107278 scopus 로고    scopus 로고
    • Intracavernosal injection of vascular endothelial growth factor induces nitric oxide synthase isoform
    • Lin CS, Ho HC, Chen KC, Lin G, Nunes L, Lue TF. Intracavernosal injection of vascular endothelial growth factor induces nitric oxide synthase isoform. BJU Int 2002; 89: 955-60.
    • (2002) BJU Int. , vol.89 , pp. 955-960
    • Lin, C.S.1    Ho, H.C.2    Chen, K.C.3    Lin, G.4    Nunes, L.5    Lue, T.F.6
  • 4
    • 0034012488 scopus 로고    scopus 로고
    • Pharmacotherapy for erectile dysfunction
    • TF Lue, KL Lee. Pharmacotherapy for erectile dysfunction. Chin Med J (Engl), 2000; 113: 291-8.
    • (2000) Chin. Med. J. (Engl) , vol.113 , pp. 291-298
    • Lue, T.F.1    Lee, K.L.2
  • 5
    • 0031932102 scopus 로고    scopus 로고
    • Effect of Korean ginseng on the rabbit corpus cavernosal smooth muscle
    • Choi YD, Xin ZC, Choi HK. Effect of Korean ginseng on the rabbit corpus cavernosal smooth muscle. Int J Impot Res 1998; 10: 37-43.
    • (1998) Int. J. Impot. Res. , vol.10 , pp. 37-43
    • Choi, Y.D.1    Xin, Z.C.2    Choi, H.K.3
  • 6
    • 0026630039 scopus 로고
    • Nitric oxide mediates relaxation in rabbit and human corpus cavernosum smooth muscle
    • Knispel HH, Goessl C, Beckman R. Nitric oxide mediates relaxation in rabbit and human corpus cavernosum smooth muscle. Urol Res 1992; 20: 253-7.
    • (1992) Urol. Res. , vol.20 , pp. 253-257
    • Knispel, H.H.1    Goessl, C.2    Beckman, R.3
  • 7
    • 0030154940 scopus 로고    scopus 로고
    • Intracavernosal pharmacotherapy: Comparison of moxisylyte and prostaglandin E1
    • Buvat J, Lemaire A, Herbaut-Buvat M. Intracavernosal pharmacotherapy: comparison of moxisylyte and prostaglandin E1. J Impt Res 1996; 8: 41-6.
    • (1996) J. Impt. Res. , vol.8 , pp. 41-46
    • Buvat, J.1    Lemaire, A.2    Herbaut-Buvat, M.3
  • 9
    • 0036596359 scopus 로고    scopus 로고
    • Intracavernous injection test by prostaglandin E1
    • Otani T. Intracavernous injection test by prostaglandin E1. Nippon Rinsho 2002; 60 (Suppl 6): 173-7.
    • (2002) Nippon Rinsho , vol.60 , Issue.SUPPL. 6 , pp. 173-177
    • Otani, T.1
  • 10
    • 0000600999 scopus 로고
    • An approved HPLC determination of flavonoids in medical plant extracts
    • Pietta PG, Mauri PL, Manera E, Ceva PL, Rava A. An approved HPLC determination of flavonoids in medical plant extracts. Chromatographia 1989; 27: 509-12.
    • (1989) Chromatographia , vol.27 , pp. 509-512
    • Pietta, P.G.1    Mauri, P.L.2    Manera, E.3    Ceva, P.L.4    Rava, A.5
  • 11
    • 0030862653 scopus 로고    scopus 로고
    • Isolation and immunomodulatory effect of flavonol glycosides from epimedium hunense
    • Liang HR, Vuorela P, Vuorela H, Hiltinen R. Isolation and immunomodulatory effect of flavonol glycosides from epimedium hunense. Plants Med 1997; 63: 316-9.
    • (1997) Plants Med. , vol.63 , pp. 316-319
    • Liang, H.R.1    Vuorela, P.2    Vuorela, H.3    Hiltinen, R.4
  • 12
    • 0037067390 scopus 로고    scopus 로고
    • Purification of icariin from the extract of Epimedium segittatum using high-speed counter-current chromatography
    • Du Q, Xia M, Ito Y. Purification of icariin from the extract of Epimedium segittatum using high-speed counter-current chromatography. J Chromatogr A 2002; 962: 239-41.
    • (2002) J. Chromatogr. A , vol.962 , pp. 239-241
    • Du, Q.1    Xia, M.2    Ito, Y.3
  • 13
    • 0025178946 scopus 로고
    • Phagocytic activity of leaves of epimedium species on mouse reticuloendothelial system
    • Linuma M, tanaka T, Sakakibara N, Mizuno M, Matsuda H, Shiomoto H, et al. Phagocytic activity of leaves of epimedium species on mouse reticuloendothelial system. Yakugaku Zasshi 1990; 110: 179-85.
    • (1990) Yakugaku Zasshi , vol.110 , pp. 179-185
    • Linuma, M.1    Tanaka, T.2    Sakakibara, N.3    Mizuno, M.4    Matsuda, H.5    Shiomoto, H.6
  • 14
    • 0028886492 scopus 로고
    • Antihepatotoxic activity of icariin, a major constituent of epimedium koreanum
    • Lee MK, Choi YJ, Sung SH, Shin DI, Kim JW, Kim YC. Antihepatotoxic activity of icariin, a major constituent of epimedium koreanum. Planta Med 1995; 61: 523-6.
    • (1995) Planta Med. , vol.61 , pp. 523-526
    • Lee, M.K.1    Choi, Y.J.2    Sung, S.H.3    Shin, D.I.4    Kim, J.W.5    Kim, Y.C.6
  • 15
    • 0029111787 scopus 로고
    • Immunoregulatory effects of the herba epimediia glycoside icariin
    • He W, Sun H, Yang B, Zhang D, Kabelitz D. Immunoregulatory effects of the herba epimediia glycoside icariin. Arzneimittelforschung 1995; 45: 910-3.
    • (1995) Arzneimittelforschung , vol.45 , pp. 910-913
    • He, W.1    Sun, H.2    Yang, B.3    Zhang, D.4    Kabelitz, D.5
  • 16
    • 0030915810 scopus 로고    scopus 로고
    • Effects of icariin on the differentiation of HL-60 cells
    • Zhao Y, Cui Z, Zhang L. Effects of icariin on the differentiation of HL-60 cells. Zhonghua Zhong Liu Za Zhi. 1997; 19: 53-5.
    • (1997) Zhonghua Zhong Liu Za Zhi , vol.19 , pp. 53-55
    • Zhao, Y.1    Cui, Z.2    Zhang, L.3
  • 17
    • 0024723740 scopus 로고
    • Action of the drug herba epimedii on testosterone of the mouse plasma and its accessory sexual organ before and after processing
    • Niu R. Action of the drug herba epimedii on testosterone of the mouse plasma and its accessory sexual organ before and after processing. Chung Kuo Chung Chao Yao Tsa Chih 1989; 14: 530-2.
    • (1989) Chung Kuo Chung Chao Yao Tsa Chih , vol.14 , pp. 530-532
    • Niu, R.1
  • 18
    • 0029286306 scopus 로고
    • Effects of Sichuan herba epimedii on the concentration of plasma middle molecular substances and sulfhydryl group of "Yang-deficiency" model animal
    • Zheng J, Luo Y, Meng X, Sun Y, Zhang Y, Dong X, et al. Effects of Sichuan herba epimedii on the concentration of plasma middle molecular substances and sulfhydryl group of "Yang-deficiency" model animal. Chung Kuo Chung Yao Tsa Chih 1995; 20: 238-9.
    • (1995) Chung Kuo Chung Yao Tsa Chih , vol.20 , pp. 238-239
    • Zheng, J.1    Luo, Y.2    Meng, X.3    Sun, Y.4    Zhang, Y.5    Dong, X.6
  • 20
    • 0013006346 scopus 로고    scopus 로고
    • Expression of Phosphodiesterase 5 in clitoris cavernosum and effect of Icariin on cGMP levels in vitro
    • Qiao L, Xin ZC, Fu J, Liu WJ, Lin GT, Chen S. Expression of Phosphodiesterase 5 in clitoris cavernosum and effect of Icariin on cGMP levels in vitro. Chin J Urol 2002; 23: 670-2.
    • (2002) Chin. J. Urol. , vol.23 , pp. 670-672
    • Qiao, L.1    Xin, Z.C.2    Fu, J.3    Liu, W.J.4    Lin, G.T.5    Chen, S.6
  • 22
    • 0030154874 scopus 로고    scopus 로고
    • Sildenafil: A orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction
    • Boolell M, Allen MJ, Ballard SA, Gepi-Attes S, Muirhead GJ, Naylor AM, et al. Sildenafil:a orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. Int J Impot Res 1996; 8: 47-52.
    • (1996) Int. J. Impot. Res. , vol.8 , pp. 47-52
    • Boolell, M.1    Allen, M.J.2    Ballard, S.A.3    Gepi-Attes, S.4    Muirhead, G.J.5    Naylor, A.M.6
  • 24
    • 0034009080 scopus 로고    scopus 로고
    • Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions
    • Soderling SH, Beavo JA. Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. Curr Opin Cell Biol 2000; 12: 174-9.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 174-179
    • Soderling, S.H.1    Beavo, J.A.2
  • 25
    • 0001918532 scopus 로고    scopus 로고
    • Identification and quantification of PDE isozymes and subtypes by molecular biological methods
    • Schudt C, Dent G, Rabe KF, editors. San Diego: Academic Press
    • Loughney K and Ferguson K. Identification and quantification of PDE isozymes and subtypes by molecular biological methods. In: Schudt C, Dent G, Rabe KF, editors. Phosphodiesterase inhibitors. San Diego: Academic Press; 1996. 99: 1-19.
    • (1996) Phosphodiesterase Inhibitors , vol.99 , pp. 1-19
    • Loughney, K.1    Ferguson, K.2
  • 26
    • 0013011070 scopus 로고
    • Human PDE5A gene encodes three PDE5 isoforms from two alternate phosphodiesterases: Functional implications of multiple isoforms
    • Lin CS, Chow S, Lau A, Tu R, Lue. Human PDE5A gene encodes three PDE5 isoforms from two alternate phosphodiesterases: functional implications of multiple isoforms. Phyiol Rev 1995; 75: 725-8.
    • (1995) Phyiol. Rev. , vol.75 , pp. 725-728
    • Lin, C.S.1    Chow, S.2    Lau, A.3    Tu, R.4    Lue, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.