Safe execution of a large-scale ozonolysis: Preparation of the bisulfite adduct of 2-hydroxyindan-2-carboxaldehyde and its utility in a reductive amination

Organic Process Research and Development

Volumn 7, Issue 2, 2003, Pages 155-160

  Ragan, John A ^a   Am Ende, David J ^a   Brenek, Steven J ^a   Eisenbeis, Shane A ^a   Singer, Robert A ^a   Tickner, Derek L ^a   Teixeira Jr , John J ^a   Vanderplas, Brian C ^a   Weston, Neil ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYINDAN 2 CARBOXALDEHYDE; ALDEHYDE DERIVATIVE; ALKENE; BISULFITE; INDANONE DERIVATIVE; SODIUM DERIVATIVE; UNCLASSIFIED DRUG; VINYL DERIVATIVE;

AMINATION; AQUEOUS SOLUTION; ARTICLE; CALORIMETRY; GRIGNARD REACTION; OZONOLYSIS; REDUCTION; SAFETY; SCALE UP;

EID: 0037358012     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op0202235     Document Type: Article

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