Bisindole alkaloids from Strychnos guianensis are effective antagonists of nicotinic acetylcholine receptors in cultured human TE671 cells

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 367, Issue 3, 2003, Pages 253-259

  Wins, Pierre ^a   Margineanu, Ilca ^a   Penelle, Jacques ^b   Angenot, Luc ^b   Grisar, Thierry ^a   Bettendorff, Lucien ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Bisquaternary compounds; Curarizing agents; Indole alkaloids; Ion fluxes; Nicotinic acetylcholine receptor; Strychnos guianensis; TE 671 cell line

Indexed keywords

5',6' DEHYDROGUIAFLAVINE; ALKALOID; BISINDOLE; CARBACHOL; CHOLINERGIC RECEPTOR; GUIACHRYSINE; GUIAFLAVINE; STRYCHNOS GUIANENSIS EXTRACT; TUBOCURARINE CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL CLONE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; DRUG ISOLATION; DRUG POTENCY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; IC 50; MEDICINAL PLANT; NEUROMUSCULAR TRANSMISSION; RECEPTOR BLOCKING; STRYCHNOS GUIANENSIS;

CARBACHOL; CELL LINE; CHOLINERGIC AGONISTS; HUMANS; INDOLE ALKALOIDS; NICOTINIC ANTAGONISTS; PLANT BARK; RECEPTORS, NICOTINIC; STRYCHNOS; TIME FACTORS;

EID: 0037357046     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-003-0692-9     Document Type: Article

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