Correction of the high blood viscosity syndrome by a mixture of diquertin and ascorbic acid in vitro and in vivo

Phytotherapy Research

Volumn 17, Issue 3, 2003, Pages 276-278

  Plotnikov, M B ^a   Aliev, O I ^a   Maslov, M Ju ^a   Vasiliev, A S ^a   Tjukavkina, N A ^b  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b I M SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY   (Russian Federation)

Author keywords

Ascorbic acid; Cerebral ischemia; Diquertin; High blood viscosity syndrome; Rheological properties of blood

Indexed keywords

ASCORBIC ACID; DIQUERTIN; GINKGO BILOBA EXTRACT; QUERCETIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD RHEOLOGY; BLOOD VISCOSITY; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG MECHANISM; DRUG MIXTURE; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; GENE EXPRESSION; HIGH BLOOD VISCOSITY SYNDROME; MALE; NONHUMAN; RAT; SHEAR RATE;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; BLOOD VISCOSITY; BRAIN ISCHEMIA; DRUG THERAPY, COMBINATION; ERYTHROCYTE AGGREGATION; FIBRINOGEN; MALE; PHYTOTHERAPY; QUERCETIN; RATS; RATS, WISTAR;

EID: 0037355936     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1113     Document Type: Article

References (19)

1. Baluda VP, Barkagan ZC, Goldberg ED. 1980. Laboratory Methods for the Investigation of Homeostasis. Krasnoe Znamja: Tomsk (in Russian).
2. Bobyreva LE. 1998. Antioxidant in complex treatment of diabetic angiopaties. Exp Clin Pharm 1: 74-80 (in Russian).
3. Chung TW, Yu JJ, Liu DZ. 1998. Reducing lipid peroxidation of erythrocyte membrane by alpha-tocopherol nicotinate plays an impotent role in improving blood rheological properties in type 2 diabetic patients with retinopathy. Diabet Med 15: 380-385.
4. Dintefass L. 1966. A preliminary outline of the blood high viscosity syndromes. Arch Intern Med 118: 427-435.
5. Francis DA, Francis TL, Roath OS. 1985. The effect of nifedipine on the heat-treated red cells. Clin Hemorheol 5: 149-153.
6. Gabrieljan ES, Akopov SA. 1985. Blood Cells and Blood Flow. Ajstan: Erevan (in Russian).
7. Groner W, Mohandas N, Bessis M. 1980. New optical technique for measuring erythrocyte deformability with the ektacytometer. Clin Chem 9: 1435-1442.
8. Hirayama T, Folmers P, Hansson R, et al. 1986. Scand J Thor Cardiovasc Surg 20: 247-252.
9. Kaplan J, Dimlich RVW, Biros MN, Hedges J. 1987. Mechanisms of ischemic cerebral injury. Resuscitation 15: 149-169.
10. Kolhir VK, Bykov VA, Baginskaja AL, et al. 1996. Antioxidant activity of Diquertin isolated from Larix gmelinii (Rupr.) Rupr. wood. Phytother Res 10: 478-482.
11. Koltringer P, Eber O, Klima G, et al. 1989. Die Mikrozirkulation unter parenteraler Ginkgo-biloba. Extrakt-Therapie. Wien Klin Wochenschr 101: 198-200.
12. Levtov VA, Regirer SA, Shadrina WCh. 1982. Rheology of Blood. Meditzina: Moscow (in Russian).
13. Ott E, Fazekas F, Tschinkel M, et al. 1983. Rheological aspects of cerebrovascular disease. Eur Neurol 22(Suppl. 1): 35-37.
14. Plotnikov MB, Koltunov AA, Aliev OI. 1996. Creation of hypeviscosity syndrome: the correlation among hemorheology parameters and their importance at cerebral ischaemia in rats. Bull Experim Biol Med 9: 274-275.
15. Plotnikov MB, Aliev OI, Popell FV. 1995. The modification of micro colourmeter MKMF-1 for registration of erythrocyte aggregation. Clin Lab Diagn 3: 457-458 (in Russian).
16. Plotnikov TM, Bazhenova TG, Plotnikov MB, Saratikov AS. 1997. The effect of cerebrocrast on microcirculation in acute transient cerebral ischemia. Rus J Exp Clin Pharm 1: 58-60.
17. Sakuta S. 1981. Blood filtrability in cerebrovascular disorders with special reference to erythrocyte deformability and ATP content. Stroke 12: 824-828.
18. Sorata Y, Tanahama V, Kimura M. 1988. Cooperation of quercetin with ascorbate in protection of photosensitized lysis of human erythrocytes in the presence of hematoporphyrin. Photochem Photobiol 48: 195-199.
19. Stoltz JE. 1982. Main determinants of red blood cell deformability, clinical and pharmacological application. Clin Hemorheol 2: 163-173.