Cytogenetic and clinicopathological analysis of soft-tissue leiomyosarcomas

Pathology International

Volumn 53, Issue 3, 2003, Pages 163-168

  Miyajima, Kimitaka ^a   Oda, Yoshinao ^a   Tamiya, Sadafumi ^a   Shimizu, Kiichi ^b   Hachitanda, Yoichi ^c   Tsuneyoshi, Masazumi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b SHIONOGI AND CO LTD   (Japan)

^c NATIONAL KYUSHU CANCER CENTER   (Japan)

Author keywords

Clinicopathology; Cytogenetic analysis; Leiomyosarcoma

Indexed keywords

ADULT; AGED; ARTICLE; CANCER GRADING; CHROMOSOME 10P; CHROMOSOME 11P; CHROMOSOME 11Q; CHROMOSOME 12P; CHROMOSOME 16Q; CHROMOSOME 17P; CHROMOSOME 19Q; CHROMOSOME 3P; CHROMOSOME 3Q; CHROMOSOME 6Q; CHROMOSOME 7P; CHROMOSOME 9P; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME REARRANGEMENT; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KARYOTYPE; LEIOMYOSARCOMA; MALE; MORPHOLOGY; MYXOSARCOMA; PRIORITY JOURNAL; SOFT TISSUE TUMOR;

ADULT; AGED; AGED, 80 AND OVER; CHROMOSOME ABERRATIONS; CHROMOSOME BANDING; FEMALE; HUMANS; LEIOMYOSARCOMA; MALE; MIDDLE AGED; NEOPLASM STAGING; SOFT TISSUE NEOPLASMS;

EID: 0037354841     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2003.01449.x     Document Type: Article

References (36)

1. Nilbert M, Mandahl N, Heim S et al. Chromosome abnormalities in leiomyosarcomas. Cancer Genet Cytogenet 1988; 34: 209-18.
2. Salt SNJ, Dal Cin P, Sandberg AA. Consistent chromosome changes in leiomyosarcoma. Cancer Genet Cytogenet 1988; 35: 47-50.
3. Boghosian L, Dal Cin P, Turc-Carel C et al. Three possible cytogenetic subgroups of leiomyosarcoma. Cancer Genet Cytogenet 1989; 43: 39-49.
4. Nilbert M, Mandahl N, Heim S et al. Complex karyotypic changes, including rearrangements of 12q13 and 14q24, in two leiomyosarcomas. Cancer Genet Cytogenet 1990; 48: 217-23.
5. Sreekantaiah C, Davis JR, Sandberg AA. Chromosomal abnormalities in leiomyosarcomas. Am J Pathol 1993; 142: 293-305.
6. Mandahl N. Cytogenetics and molecular genetics of bone and soft tissue tumors. Adv Cancer Res 1996; 69: 63-99.
7. El-Rifai W, Sarlomo-Rikala M, Knuutila S, Miettinen M. DNA copy number changes in development and progression in leiomyosarcomas of soft tissues. Am J Pathol 1998; 153: 985-90.
8. Mertens F, Fletcher CD, Cin PD et al. Cytogenetic analysis of 46 pleomorphic soft tissue sarcomas and clinical features: a report of the CHAMP Study Group. Genes Chromosomes Cancer 1998; 22: 16-25.
9. Salm R, Evans DJ. Myxoid leiomyosarcoma. Histopathology 1985; 9: 159-69.
10. Fletcher CDM. Pleomorphic malignant fibrous histiocytoma: fact or fiction? A critical reappraisal based on 159 tumors diagnosed as pleomorphic sarcoma. Am J Surg Pathol 1992; 16: 213-28.
11. Oda Y, Miyazima K, Kawaguchi K et al. Pleomorphic leiomyosarcoma: Clinicopathologic and immunohistochemical study with special emphasis on its distinction from ordinary leiomyosarcoma and malignant fibrous histiocytoma. Am J Surg Pathol 2001; 25; 1030-38.
12. Miyajima K, Oda Y, Oshiro Y et al. Clinicopathologic prognostic factors in soft tissue leiomyosarcoma: a multivariate analysis. Histopathology 2002; 40: 353-9.
13. Coindre JM, Trojani M, Contesso G et al. Reproducibility of a histopathologic grading system for adult soft tissue sarcoma. Cancer 1986; 58: 306-9.
14. Fleming ID, Cooper JS, Henson DE. American Joint Committee on Cancer (AJCC) Staging Manual, 5th edn. Philadelphia; Lippincott, 1997; 149-56.
15. Sonobe H, Iwata J, Takeki K et al. A giant cell angiofibroma involving 6q. Cancer Genet Cytogenet 2000; 116: 47-9.
16. Mandahl N, Fletcher CDM, Dal Cin P et al. Comparative cytogenetic study of spindle cell and pleomorphic leiomyosarcomas of soft tissues. A report from the CHAMP Study Group. Cancer Gene T Cytogenet 1999; 116: 66-73.
17. Russell WO, Cohen J, Enzinger F et al. A clinical and pathological staging system for soft tissue sarcomas. Cancer 1977; 40: 1562-70.
18. Trojani M, Contesso G, Coindre JM et al. Soft-tissue sarcomas of adults; study of pathological prognostic variables and definition of a histopathological grading system. Int J Cancer 1984; 33: 37-42.
19. Coindre JM, Bui NB, Bonichon F, Mascarel I, Trojani M. Histopathologic grading in spindle cell soft tissue sarcomas. Cancer 1988; 61: 2305-9.
20. Weiss SW, Goldblum JR. Extragastrointestinal stromal tumors. In: Weiss SW, Goldblum JR, eds. Enzinger and Weiss's Soft Tissue Tumors, 4th edn. St Louis: Mosby, 2001; 749-68.
21. Fletcher JA, Morton CC, Pavelka K, Lage JM. Chromosome aberrations in uterine smooth muscle tumors; Potential diagnostic relevance of cytogenetic instability. Cancer Res 1990; 50: 4092-7.
22. Hennig Y, Deichert U, Stern C et al. Structural aberrations of chromosome 6 in three uterine smooth muscle tumors. Cancer Genet Cytogenet 1996; 87: 148-51.
23. Tallini G, Vanni R, Manfioletti G et al. HMGI-C and HMGY (Y) immunoreactivity correlates with cytogenetic abnormalities in lipomas, pulmonary chondroid hamartomas, endometrial polyps and uterine leiomyomas and is compatible with rearrangement of the HMGI-C and HMGI (Y) genes. Laboratory Invest 2000; 80: 359-69.
24. Kuruzelock RP, Murphy EC, Strong LC, Naylor SL, Hansen MF. Localization of a novel tumor suppressor locus on human chromosome 3q important in osteosarcoma tumorigenesis. Cancer Res 1997; 57: 106-9.
25. Walker GJ, Palmer JM, Walters MK, Nancarrow DJ, Parsons PG, Hayward NK. Simple tandem repeat allelic deletions confirm the preferential loss of distal chromosome 6q in melanoma. Int J Cancer 1994; 58: 203-6.
26. Orphanos V, McGown G, Hey Y, Boyle JM, Santibanez-Koref M. Proximal 6q, a region showing allele loss in primary breast cancer. Br J Cancer 1995; 71: 290-93.
27. Theile M, Seitz S, Arnold W et al. A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer. Oncogene 1996; 13: 677-85.
28. Colitti CV, Rodabaugh KJ, Welch WR, Berkowitz RS, Mok SC. A novel 4 cM minimal deletion unit on chromosome 6q25.1-q25.2 associated with high grade invasive epithelial ovarian carcinomas. Oncogene 1998; 16: 555-9.
29. Shridhar V, Staub J, Huntley B et al. A novel region of deletion on chromosome 6q23.3 spanning less than 500 Kb in high grade invasive epithelial ovarian cancer. Oncogene 1999; 18: 3913-18.
30. Peier AM, Meloni AM, Erling MA, Sandberg AA. Involvement of chromosome 7 in Wilms tumor. Cancer Genet Cytogenet 1995; 79: 92-4.
31. Miozzo M, Perotti D, Minoletti F et al. Mapping of a putative tumor suppressor locus to proximal 7p in Wilms tumors. Genomics 1996; 37: 310-15.
32. Steenman M, Redeker B, De Meulemeester M et al. Comparative genomic hybridization analysis of Wilms tumors. Cytogenet Cell Genet 1997; 77: 296-303.
33. Powlesland RM, Charles AK, Malik KTA et al. Loss of heterozygosity at 7p in Wilms' tumour development. Br J Cancer 2000; 82: 323-9.
34. Ramsom DT, Ritland SR, Moertel CA et al. Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligo-astrocytomas. Genes Chromosomes Cancer 1992; 5: 357-74.
35. Kimmelman AC, Ross DA, Liang BC. Loss of heterozygosity of chromosome 10p in human gliomas. Genomics 1996; 34: 250-54.
36. Man S, Ellis IO, Sibbering M, Blamey RW, Brook JD. High levels of allele loss at the FHIT and ATM genes in non-comedo ductal carcinoma in situ and grade I tubular invasive breast cancers. Cancer Res 1996; 56: 5484-9.