Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 367, Issue 3, 2003, Pages 245-252

  Depoortere, Inge ^a   Thijs, Theo ^a   Thielemans, Leen ^a   Peeters, Theo L ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Electrical field stimulation; Nitric oxide; Prostaglandin; Rebound response; Serotonin; Substance P; TNBS colitis

Indexed keywords

INDOMETACIN; METITEPINE; N(G) NITROARGININE METHYL ESTER; NEUROKININ 1 RECEPTOR ANTAGONIST; NOLPITANTIUM; PROSTAGLANDIN SYNTHASE INHIBITOR; SEROTONIN; TRINITROBENZENESULFONIC ACID;

ANIMAL TISSUE; ARTICLE; CHOLINERGIC TRANSMISSION; COLITIS; COLON; CONTROLLED STUDY; ELECTROSTIMULATION; ENZYME INHIBITION; FEMALE; INFLAMMATION; INTESTINE MUSCLE; MALE; NERVE TRACT; NEUROTRANSMISSION; NONHUMAN; PHARMACOLOGICAL BLOCKING; REBOUND; RECEPTOR BLOCKING; STIMULUS RESPONSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; COLITIS; CYCLOOXYGENASE INHIBITORS; ELECTRIC STIMULATION; FEMALE; INDOMETHACIN; MALE; METHIOTHEPIN; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PIPERIDINES; QUINUCLIDINES; RABBITS; RECEPTORS, NEUROKININ-1; RECEPTORS, PURINERGIC P2; SEROTONIN ANTAGONISTS; SUBSTANCE P; SURAMIN; TRINITROBENZENESULFONIC ACID;

EID: 0037354517     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-003-0696-5     Document Type: Article

References (30)

1. Bauer V, Matusak O, Bazekova M, Benes L, Kuriyama H (1982) Role of Ca2+ in non-cholinergic, non-adrenergic responses to nerve stimulation of the guinea-pig small intestine. Naunyn-Schmiedebergs Arch Pharmacol 319:115-120.
2. Bennett MR (1966) Rebound excitation of the smooth muscle cells of the guinea-pig taenia coli after stimulation of intramural inhibitory nerves. J Physiol 185:124-131
3. Bossone C, Hosseini JM, Pineiro-Carrero V, Shea-Donohue T (2001) Alterations in spontaneous contractions in vitro after repeated inflammation of rat distal colon. Am J Physiol 280: G949-G957
4. Briejer MR, Akkermans LM, Schuurkes JA (1995) Interactions of serotonin with multiple receptors and neurotransmitters in the guinea-pig isolated colon. Arch Int Pharmacodyn Ther 329: 121-133
5. Burnstock G, Cocks T, Paddle B, Staszewska-Barczak J (1975) Evidence that prostaglandin is responsible for the 'rebound contraction' following stimulation of non-adrenergic, noncholinergic ('purinergic') inhibitory nerves. Eur J Pharmacol 31:360-362
6. Bywater RA, Holman ME, Taylor GS (1981) Atropine-resistant depolarization in the guinea-pig small intestine. J Physiol 316:369-378
7. Camilleri M (2002) Serotonergic modulation of visceral sensation: lower gut. Gut 51:81-86
8. Den Hertog A, van den Akker J (1979) Effects of prostaglandin E2 and indomethacin on the rebound of the guinea-pig taenia coli. Eur J Pharmacol 55:143-148
9. Depoortere I, Van Assche G, Thijs T, Geboes K, Peeters TL (1999) Differential changes in ACh-, motilin-, substance P-, and K(+)-induced contractility in rabbit colitis. Am J Physiol 277:G61-G68
10. Depoortere I, Thijs T, Van Assche G, Keith JC Jr, Peeters TL (2000a) Dose-dependent effects of recombinant human interleukin-11 on contractile properties in rabbit 2,4,6-trinitrobenzene sulfonic acid colitis. J Pharmacol Exp Ther 294:983-990
11. Depoortere I, Thijs T, Thielemans L, Van Assche G, Peeters TL (2000b) The inhibitory effects of 5-HT agonists on the rabbit colon are reversed to excitatory effects by TNBS-colitis. Neurogastroenterol Motil 12:271
12. Depoortere I, Thijs T, Peeters TL (2002) Generalized loss of inhibitory innervation reverses serotonergic inhibition into excitation in a rabbit model of TNBS-colitis. Br J Pharmacol 135: 2011-2019
13. Franck H, Kong ID, Shuttleworth CW, Sanders KM (1999) Rebound excitation and alternating slow wave patterns depend upon eicosanoid production in canine proximal colon. J Physiol 520:885-895
14. Geboes K, Collins S (1998) Structural abnormalities of the nervous system in Crohn's disease and ulcerative colitis. Neurogastroenterol Motil 10:189-202
15. Gelal A, Guven H (1998) Characterization of 5-HT receptors in rat proximal colon. Gen Pharmacol 30:343-346
16. Hogaboam CM, Jacobson K, Collins SM, Blennerhassett MG (1995) The selective beneficial effects of nitric oxide inhibition in experimental colitis. Am J Physiol 268:G673-G684
17. Kadlec O, Masek K, Sefema I (1974) A modulating role of prostaglandins in contractions of the guinea-pig ileum. Br J Pharmacol 51:565-570
18. Kannan MS, Jager LP, Daniel EE (1985) Electrical properties of smooth muscle cell membrane of opossum esophagus. Am J Physiol 248:G342-346
19. Lecci A, De Giorgio R, Bartho L, Sternini C, Tramontana M, Corinaldesi R, Giuliani S, Maggi CA (1999) Tachykinin NK(1)receptor-mediated inhibitory responses in the guinea-pig small intestine, Neuropeptides 33:91-97
20. Lu G, Qian X, Berezin I, Telford GL, Huizinga JD, Sarna SK (1997) Inflammation modulates in vitro colonic myoelectric and contractile activity and interstitial cells of Cajal. Am J Physiol 273:G1233-G1245
21. Mizuta Y, Isomoto H, Takahashi T (2000) Impaired nitrergic innervation in rat colitis induced by dextran sulfate sodium. Gastroenterology 118:714-723
22. Oshima S, Fujimura M, Fukimiya M (1999) Changes in number of serotonin-containing cells and serotonin levels in the intestinal mucosa of rats with colitis induced by dextran sodium sulfate. Histochem Cell Biol 112:257-263
23. Prins NH, Briejer MR, Schuurkes JA (1997) Characterization of the contraction to 5-HT in the canine colon longitudinal muscle. Br J Pharmacol 120:714-720
24. Roberts PJ, Morgan K, Miller R, Hunter JO, Middleton SJ (2001) Neuronal COX-2 expression in human myenteric plexus in active inflammatory bowel disease. Gut 48:468-472
25. Sanders KM, Smith TK (1986) Enteric neural regulation of slow waves in circular muscle of the canine proximal colon. J Physiol 377:297-313
26. Shuttleworth CW, Sanders KM, Keef KD (1993) Inhibition of nitric oxide synthesis reveals non-cholinergic excitatory neurotransmission in the canine proximal colon. Br J Pharmacol 109: 739-747
27. Venkova K, Krier J (1994) A nitric oxide and prostaglandin-dependent component of NANC off-contractions in cat colon. Am J Physiol 266:G40-G47
28. Ward SM, Dalziel HH, Thornbury KD, Westfall DP, Sanders KM (1992) Nonadrenergic, noncholinergic inhibition and rebound excitation in canine colon depend on nitric oxide. Am J Physiol 262:G237-G243
29. Woollard DJ, Bornstein JC, Furness JB (1994) Characterization of 5-HT receptors mediating contraction and relaxation of the longitudinal muscle of guinea-pig distal colon in vitro. Naunyn-Schmiedebergs Arch Pharmacol 349:455-462
30. Zagorodnyuk V, Maggi CA (1998) Pharmacological evidence for the existence of multiple P2 receptors in the circular muscle of guinea-pig colon. Br J Pharmacol 123:122-128