Lack of association of β2-glycoprotein I polymorphisms Val247Leu and Trp316Ser with antiphospholipid antibodies in patients with thrombosis and pregnancy complications

British Journal of Haematology

Volumn 120, Issue 6, 2003, Pages 1066-1072

  Camilleri, Raymond S ^a,c   Mackie, Ian J ^a   Humphries, Steve E ^b   Machin, Samuel J ^a   Cohen, Hannah ^a  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Antiphospholipid antibodies; Beta2 glycoprotein I; Polymorphisms; Pregnancy complications; Thrombosis

Indexed keywords

BETA2 GLYCOPROTEIN 1; BETA2 GLYCOPROTEIN 1 ANTIBODY; CARDIOLIPIN ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; LEUCINE; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY; TRYPTOPHAN; VALINE; AUTOANTIBODY; GLYCOPROTEIN;

ADOLESCENT; ADULT; AGED; ALLELE; ANTIBODY PRODUCTION; ANTIBODY SCREENING; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; CAUCASIAN; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; ETHNIC GROUP; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREGNANCY COMPLICATION; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; THROMBOSIS; CASE CONTROL STUDY; GENETIC POLYMORPHISM; GENETICS; IMMUNOLOGY; MIDDLE AGED; PREGNANCY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, ANTICARDIOLIPIN; ANTIBODIES, ANTIPHOSPHOLIPID; AUTOANTIBODIES; BETA 2-GLYCOPROTEIN I; CASE-CONTROL STUDIES; FEMALE; GLYCOPROTEINS; HUMANS; LUPUS COAGULATION INHIBITOR; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; THROMBOSIS;

EID: 0037353936     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04187.x     Document Type: Article

References (44)

1. 2-glycoprotein I antibodies in patients with primary antiphospholipid syndrome. Rheumatology, 38, 721-723.
2. Blank, M., Shoenfeld, Y., Cabilly, S., Heldman, Y., Fridkin, M. & Katchalski-Katzir, E. (1999) Prevention of experimental antiphospholipid syndrome and endothelial cell activation by synthetic peptides. Proceedings of the National Academy of Sciences of the United States of America, 96, 5164-5168.
3. Bouma, B., de Groot, P.G., van den Elsen, J.M., Ravelli, R.B., Schouten, A., Simmelink, M.J., Derksen, R.H., Kroon, J. & Gros, P. (1999) Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure. EMBO Journal, 18, 5166-5174.
4. Galli, M., Comfurius, P., Maassen, C., Hemker, H.C., de Baets, M.H., van Breda-Vriesman, P.J., Barbui, T., Zwaal, R.F. & Bevers, E.M. (1990) Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor. Lancet, 335, 1544-1547.
5. 2GPI in antibody binding. Journal of Immunology, 160, 3917-3923.
6. Greaves, M., Cohen, H., Machin, S.J. & Mackie, I. (2000) Guidelines on the investigation and management of the antiphospholipid syndrome. British Journal of Haematology, 109, 704-715.
7. 2-glycoprotein I. Journal of Autoimmunity, 15, 87-89.
8. Harris, E.N., Chan, J.K., Asherson, R.A., Aber, V.R., Gharavi, A.E. & Hughes, G.R. (1986) Thrombosis, recurrent foetal loss, and thrombocytopenia. Predictive value of the anticardiolipin antibody test. Archives of Internal Medicine, 146, 2153-2156.
9. 2-glycoprotein I antibodies in the antiphosphollpid syndrome. Arthritis and Rheumatism, 42, 1655-1661.
10. 2-glycoprotein I antibodies. Thrombosis and Haemostasis, 80, 791-797.
11. 2-glycoprotein I contains a phospholipid binding site (Cys281-Cys288) and a region recognised by anticardiolipin antibodies. Journal of Immunology, 152, 653-659.
12. 2-glycoprotein I as an anticardiolipin cofactor determined using mutants expressed by a baculovirus system. Blood, 87, 3262-3270.
13. 2GPI. Proceedings of the National Academy of Sciences of the United States of America, 95, 15542-15546.
14. 2GPI to determine fine antigenic specificity of antiphospholipid autoantibodies. Journal of Autoimmunity (Abstracts from the International Symposium on Antiphospholipid Antibodies), 15, a19 (PD3).
15. 2-glycoprotein I). American Journal of Human Genetics, 42, 452-457.
16. 2-glycoprotein I) to anionic phospholipids. Human Genetics, 95, 385-388.
17. 2-glycoprotein I) affects the occurrence of antiphospholipid antibodies and apolipoprotein H concentrations in systemic lupus erythematosus. Lupus, 8, 742-750.
18. 2-GPI recognized by anticardiolipin antibodies. Lupus, 7, s14-s17.
19. 2-glycoprotein I cDNA. FEBS Letters, 289, 183-186.
20. 2-glycoprotein I. Proceedings of the National Academy of Sciences of the United States of America, 81, 3640-3644.
21. 2-glycoprotein I antibody complexes. Journal of Biological Chemistry, 276, 3060-3067.
22. 2-glycoprotein I binding antibodies are associated with a history of thromboembolic complications in patients with SLE and primary antiphospholipid syndrome. British Journal of Rheumatology, 34, 1031-1036.
23. McNally, T., Purdy, G., Mackie, I.J., Machin, S.J. & Isenberg, D.A. (1995b) The use of an anti-beta 2-glycoprotein-I assay for discrimination between anticardiolipin antibodies associated with infection and increased risk of thrombosis. British Journal of Haematology, 91, 471-473.
24. 2-glycoprotein I. Lupus, 7, s176.
25. 2-glycoprotein I. Thrombosis and Haemostasis, 86, 590-595.
26. 2-glycoprotein I (apolipoprotein H). Proceedings of the National Academy of Sciences of the United States of America, 87, 4120-4124.
27. Matsuura, E., Igarashi, Y., Fujimoto, M., Ichikawa, K. & Koike, T. (1990) Anticardiolipin co-factor(s) and differential diagnosis of autoimmune disease. Lancet, 336, 177-178.
28. 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface. Journal of Experimental Medicine, 179, 457-462.
29. 2-glycoprotein I). Gene, 108, 293-298.
30. 2-glycoprotein I) and their impact on cardiolipin binding. Journal of Autoimmunity (Abstracts from the International Symposium on Antiphospholipid Antibodies), 15, a34 (P14).
31. 2-glycoprotein I. Thrombosis and Haemostasis, 67, 499-502.
32. 2-glycoprotein-I to human serum lipoproteins: distribution among density fractions. FEBS Letters, 102, 183-186.
33. 2-glycoprotein I antibodies from autoantibody and immunized sources. Journal of Autoimmunity, 15, 91-96.
34. Rooney, A.M., McNally, T., Mackie, I.J. & Machin, S.J. (1994) The Taipan snake venom time: a new test for lupus anticoagulant. Journal of Clinical Pathology, 47, 497-501.
35. 2-glycoprotein I. Journal of Clinical Investigation, 90, 1100-1104.
36. 2-glycoprotein I in the absence of phospholipid. Importance of Ag density and bivalent binding. Journal of Immunology, 154, 954-960.
37. 2-glycoprotein I) which affect phospholipid binding. Human Molecular Genetics, 6, 311-316.
38. 2 globulin des human serums. Die Naturwissenschaften, 48, 719.
39. 2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome. EMBO Journal, 18, 6228-6239.
40. 2-glycoprotein I. Biochemical Journal, 277, 387-391.
41. Steinkasserer, A., Dörner, C., Würzner, R. & Sim, R.B. (1993) Human β2-glycoprotein I: molecular analysis of DNA and amino acid polymorphism. Human Genetics, 91, 401-402.
42. Tan, E.M., Cohen, A.S., Fries, J.F., Masi, A.T., McShane, D.J., Rothfield, N.F., Schaller, J.G., Talal, N. & Winchester, R.J. (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis and Rheumatism, 25, 1271-1277.
43. 2-glycoprotein I antibodies derived from patients with the antiphospholipid syndrome. Journal of Immunology, 155, 1629-1636.
44. Willems, G.M., Janssen, M.P., Pelsers, M.M., Comfurius, P., Galli, M., Zwaal, R.F. & Bevers, E.M. (1996) Role of divalency in the high-affinity binding of anticardiolipin antibody-beta 2-glycoprotein I complexes to lipid membranes. Biochemistry, 35, 13833-13842.