Butein suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture

Journal of Pharmacy and Pharmacology

Volumn 55, Issue 3, 2003, Pages 347-352

  Woo, Sun Wook ^a   Lee, Sung Hee ^a   Kang, Hee Chul ^a   Park, Eun Jeon ^a   Zhao, Yu Zhe ^a   Kim, Youn Chul ^a   Sohn, Dong Hwan ^a  

^a Wonkwang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALPHA ACTIN; ALPHA1(I) COLLAGEN; BUTEIN; COLLAGEN; COLLAGEN TYPE 1; COLLAGENASE 3; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; CELL ACTIVATION; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION; CELL VIABILITY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS; DRUG EFFECT; GENE EXPRESSION; IN VITRO STUDY; LIVER CELL; LIVER FIBROSIS; NONHUMAN; RAT; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; WESTERN BLOTTING;

ACTINS; ANIMALS; ANTIMETABOLITES; BLOTTING, WESTERN; BROMODEOXYURIDINE; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; CHALCONE; CHALCONES; COLLAGEN; COLLAGENASES; DNA; FIBROBLASTS; LIVER; MALE; MATRIX METALLOPROTEINASE 13; PHOSPHODIESTERASE INHIBITORS; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 0037353658     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/002235702658     Document Type: Article

References (28)

1. Benyon, R. C.,Iredale, J. P., Goddard, S., Winwood, P. J., Arthur, M. J. (1996) Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver. Gastroenterology 110: 821-831
2. Casini, A., Ceni, E., Salzano, R., Milani, S., Schuppan, D., Surrenti, C. (1994) Acetaldehyde regulates the gene expression of matrix-metalloproteinase-1 and -2 in human fat-storing cells. Life Sci. 55: 1311-1316
3. Cheng, Z. J., Kuo, S. C., Chan, S. C., Ko, F. N., Teng, C. M. (1998) Antioxidant properties of butein isolated from Dalbergia odorifera. Biochim. Biophys. Acta 1392: 291-299
4. Friedman, S. L. (1993) Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N. Engl. J. Med. 328: 1818-1835
5. Friedman, S. L. (2000) Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J. Biol. Chem. 275: 2247-2250
6. Friedman, S. L., Roll, F. J., Boyles, J., Bissell, D. M. (1985) Hepatic lipocytes: The principal collagen-producing cells of normal rat liver. Proc. Natl Acad. Sci. USA 82: 8681-8685
7. Gressner, A. M. (1995) Cytokines and cellular crosstalk involved in the activation of fat-storing cells. J. Hepatol. 22: 28-36
8. Gressner, A. M., Bachem, M. G. (1990) Cellular sources of noncollagenous matrix proteins: Role of fat-storing cells in fibrogenesis. Semin. Liver Dis. 10: 30-46
9. Inoue, T., Jackson, E. K. (1999) Strong antiproliferative effects of baicalein in cultured rat hepatic stellate cells. Eur. J. Pharmacol. 378: 129-135
10. Iredale, J. P., Benyon, R. C., Arthur, M. J., Ferris, W. F., Alcolado, R., Winwood, P. J., Clark, N. Murphy, G. (1996) Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis. Hepatology 24: 176-184
11. Kang, H. C., Nan, J. X., Park, P. H., Kim, Y. J., Lee, S. H., Woo, S. W., Zhao, Y. Z., Park, E. J., Sohn, D. H. (2002) Curcumin inhibits collagen synthesis and hepatic stellate cell activation in-vivo and in-vitro. J. Pharm. Pharmacol. 54: 119-126
12. Kawada, N., Seki, S., Inoue, M., Kuroki, T. (1998) Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells. Hepatology 27: 1265-1274
13. Knittel, T., Schuppan, D., Meyer Zum Buschenfelde, K. H., Ramadori, G. (1992) Differential expression of collagen types I, III, and IV by fat-storing (Ito) cells in vitro. Gastroenterology 102: 1724-1735
14. Lee, K. S., Buck, M., Houghlum, K., Chojkier, M. (1995) Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression. J. Clin. Invest. 96: 2461-2468
15. Lee, S. H., Nan, J. X., Sohn, D. H. (2001) Tetrandrine prevents tissue inhibitor of metalloproteinase-1 messenger RNA expression in rat liver fibrosis. Pharmacol. Toxicol. 89: 210-211
16. Milani, S., Herbst, H., Schuppan, D., Grappone, C., Pellegrini, G., Pinzani, M., Casini, A., Calabro, A., Ciancio, G., Stefanini, F. (1994) Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver. Am. J. Pathol. 144: 528-537
17. Park, P. H., Nan, J. X., Park, E. J., Kang, H. C., Kim, J. Y., Ko, G., Sohn, D. H. (2000) Effect of tetrandrine on experimental hepatic fibrosis induced by bile duct ligation and scission in rats. Pharmacol. Toxicol. 87: 261-268
18. Parola, M., Pinzani, M., Casini, A., Albano, E., Poli, G., Gentilini, A., Gentilini, P., Dianzani, M. U. (1993) Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells. Biochem. Biophys. Res. Commun. 194: 1044-1050
19. Pietrangelo, A. (1996) Metals, oxidative stress, and hepatic fibrogenesis. Semin. Liver Dis. 16: 13-30
20. Pinzani, M., Gesualdo, L., Sabbah, G. M., Abboud, H. E. (1989) Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells. J. Clin. Invest. 84: 1786-1793
21. Ramadori, G. (1991) The stellate cell (Ito-cell, fat-storing cell, lipocyte, perisinusoidal cell) of the liver. New insights into pathophysiology of an intriguing cell. Virchows Arch. B Cell Pathol. 61: 147-158
22. Ramanathan, R., Das, N. P., Tan, C. H. (1994) Effects of gamma-linolenic acid, flavonoids, and vitamins on cytotoxicity and lipid peroxidation. Free Radic. Biol. Med. 16: 43-48
23. Rojkind, M., Giambrone, M. A., Biempica, L. (1979) Collagen types in normal and cirrhotic liver. Gastroenterology 76: 710-719
24. Sogawa, S., Nihro, Y., Ueda, H., Miki, T., Matsumoto, H., Satoh, T. (1994) Protective effects of hydroxychalcones on free radical-induced cell damage. Biol. Pharm. Bull. 17: 251-256
25. Svegliati-Baroni, G., Saccomanno, S., Van Goor, H., Jansen, P., Benedetti, A., Moshage, H. (2001) Involvement of reactive oxygen species and nitric oxide radicals in activation and proliferation of rat hepatic stellate cells. Liver 21: 1-12
26. Woo, S. W., Nan, J. X., Lee, S. H., Park, E. J., Zhao, Y. Z., Sohn, D. H. (2002) Aloe emodine suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture. Pharmacol. Toxicol. 90: 193-198
27. Yit, C. C., Yang, E. B., Tang, W. Y., Wong, K. P., Mack, P. (1994) Cytotoxic effect of butein on human colon adenocarcinoma cell proliferation. Cancer Lett. 82: 65-72
28. Zhang, K., Yang, E. B., Tang, W. Y., Wong, K. P., Mack, P. (2002) Inhibition of glutathione reductase by plant polyphenols. Biochem. Pharmacol. 54:1047-1053