A small whole-body exposure chamber for laboratory use

Inhalation Toxicology

Volumn 15, Issue 3, 2003, Pages 251-263

  O'Shaughnessy, Patrick T ^a   Achutan, Chandran ^a   O'Neill, Marsha E ^a   Thorne, Peter S ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM; STAINLESS STEEL;

AEROSOL; AIR QUALITY CONTROL; AIRFLOW; ARTICLE; DYNAMICS; LABORATORY; PARTICULATE MATTER; PERFORMANCE; PRIORITY JOURNAL; VALIDATION PROCESS;

AIR POLLUTANTS; ANIMALS; ANIMALS, LABORATORY; ATMOSPHERE EXPOSURE CHAMBERS; EQUIPMENT DESIGN; INHALATION EXPOSURE; LABORATORIES; MICE; TOXICITY TESTS;

EID: 0037352661     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.1080/08958370304504     Document Type: Article

References (12)

1. Cannon, W. C., Blanton, E. F., and McDonald, K. E. 1983. The flow-past chamber: an improved nose-only exposure system for rodents. Am. Ind. Hyg. Assoc. J. 44(12):923-928.
2. Cheng, Y.-S., Barr, E. B., Carpenter, R. L., Benson, J. M., and Hobbs, C. H. 1989. Improvement of aerosol distribution in whole-body inhalation exposure chambers. Inhal. Toxicol. 1:153-166.
3. Cheng, Y.-S., and Moss, O. R. 1995. Inhalation exposure systems. In Concepts in inhalation toxicology, 2nd ed., eds. R. O. McClellan and R. F. Henderson, pp. 25-66. Washington, DC: Taylor & Francis.
4. Hemenway, D. R., Carpenter, R. L., and Moss, O. R. 1982. Inhalation toxicology chamber performance: a quantitative model. Am. Ind. Hyg. Assoc. J. 43:120-127.
5. Hemenway, D. R., Sylwester, D., Gale, P. N., Vacek, P., and Evans, J. N. 1983. Effectiveness of animal rotation in achieving uniform dust exposures and lung dust deposition in horizontal flow chambers. Am. Ind. Hyg. Assoc. J. 44:655-658.
6. Jakab, G. J., and Hemenway, D. R. 1989. Restraint of animals required for nose-only inhalation toxicological studies suppresses pulmonary antibacterial defenses. Inhal. Toxicol. 1:289-300.
7. King-Herbert, A. P., Hesterburg, T. W., Thevenaz, P. P., Hamm, T. E., Moss, O. R., Janszen, D. B., and Everitt, J. I. 1997. Effects of immobilization restraint on Syrian golden hamsters. Lab. Anim. Sci. 47(4):362-366.
8. Levenspiel, O. 1972. Chemical reaction engineering, 2nd ed. New York: John Wiley.
9. Mokler, B. V. and White, R. K. 1983. Quantitative standard for exposure chamber integrity. Am. Ind. Hyg. Assoc. J. 44:292-295.
10. Pauluhn, J. 1994. Validation of an improved nose-only exposure system for rodents. J. Appl. Toxicol. 14(1):55-62.
11. Stephenson, E. H., Moeller, R. B., York, C. G., and Young, H. W. 1988. Nose-only versus whole-body aerosol exposure for induction of upper respiratory infections of laboratory mice. Am. Ind. Hyg. Assoc. J. 49(3):128-135.
12. Thorne, P. S. 2000. Inhalation toxicology models of endotoxin and bioaerosol-induced inflammation. Toxicology 152:13-23.