Studies on the Escherichia coli glucose-specific permease, PtsG, with a point mutation in its N-terminal amphipathic leader sequence

Microbiology

Volumn 149, Issue 3, 2003, Pages 763-771

  Aboulwafa, Mohammad ^a,b   Chung, Yong Joon ^a,c   Wai, Homan Henry ^a   Saier Jr , Milton H ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Ain Shams University   (Egypt)

^c Jeonju University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DETERGENT; GLUCOSE; PERMEASE; PHOSPHOTRANSFERASE; SIGNAL PEPTIDE; SUGAR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BIOCHEMISTRY; CARBOHYDRATE METABOLISM; CATALYSIS; CELL MEMBRANE; CONTROLLED STUDY; DIFFUSION; ENZYME ACTIVATION; ENZYME CONFORMATION; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE ISOLATION; GENE MUTATION; GENE REPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHENOTYPE; PLEIOTROPY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT;

DETERGENTS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; PHOSPHOENOLPYRUVATE SUGAR PHOSPHOTRANSFERASE SYSTEM; PHOSPHORYLATION; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN SORTING SIGNALS; SUBSTRATE SPECIFICITY; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; PROKARYOTA;

EID: 0037352560     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.25731-0     Document Type: Article

References (29)

1. Aboulwafa, M. & Saier, M. H., Jr (2002). Dependency of sugar transport and phosphorylation by the phosphoenolpyruvate-dependent phosphotransferase system on membranous phosphatidyl glycerol in Escherichia coli: studies with a pgsA mutant lacking phosphatidyl glycerophosphate synthase. Res Microbiol 153, 667-677.
2. Ashworth, J. M. & Kornberg, H. L. (1966). The anaplerotic fixation of carbon dioxide by Escherichia coli. Proc R Soc Lond Ser B 65, 179-188.
3. Bogdanov, M. & Dowhan, W. (1999). Lipid-assisted protein folding. J Biol Chem 274, 36827-36830.
4. Bogdanov, M., Heacock, P. N. & Dowhan, W. (2002). A polytopic membrane protein displays a reversible topology dependent on membrane lipid composition. EMBO J 21, 2107-2116.
5. Gegley, G. S., Warner, K. A., Arents, J. C., Postma, P. W. & Jacobson, G. R. (1996). Isolation and characterization of a mutation that alters the substrate specificity of the Escherichia coli glucose permease. J Bacteriol 178, 940-942.
6. Kornberg, H. L., Lambourne, L. T. M. & Sproul, A. A. (2000). Facilitated diffusion of fructose via the phosphoenolpyruvate/glucose phosphotransferase system of Escherichia coli. Proc Natl Acad Sci U S A 97, 1808-1812.
7. Lee, S.-J., Boos, W., Bouché, J.-P. & Plumbridge, J. (2000). Signal transduction between a membrane-bound transporter, PtsG, and a soluble transcription factor, Mlc, of Escherichia coli. EMBO J 19, 5353-5361.
8. Nam, T. W., Cho, S. H., Shin, D. & 8 other authors (2001). The Escherichia coli glucose transporter enzyme IICB(Glc) recruits the global repressor Mlc. EMBO J 20, 491-498.
9. Glc) component of the Escherichia coli phosphotransferase system. J Bacteriol 182, 4437-4442.
10. Plumbridge, J. (1999). Expression of the phosphotransferase system both mediates and is mediated by Mlc regulation in Escherichia coli. Mol Microbiol 33, 260-273.
11. Plumbridge, J. (2000). A mutation which affects both the specificity of PtsG sugar transport and the regulation of ptsG expression by Mlc in Escherichia coli. Microbiology 146, 2655-2663.
12. Plumbridge, J. (2001). Regulation of PTS gene expression by the homologous transcriptional regulators, Mlc and NagC, in Escherichia coli (or how two similar repressors can behave differently). J Mol Microbiol Biotechnol 3, 371-380.
13. Reidl, J. & Boos, W. (1991). The malX malY operon of Escherichia coli encodes a novel Enzyme II of the phosphotransferase system recognizing glucose and maltose and an enzyme abolishing the endogenous induction of the maltose system. J Bacteriol 173, 4862-4876.
14. Saier, M. H., Jr (1989). Protein phosphorylation and allosteric control of inducer exclusion and catabolite repression by the bacterial phosphoenolpyruvate : sugar phosphotransferase system. Microbiol Rev 53, 109-120.
15. Saier, M. H., Jr & McCaldon, P. (1988). Statistical and functional analyses of viral and cellular proteins with N-terminal amphipathic α-helices with large hydrophobic moments. Importance to macromolecular recognition and organellar targeting. J Bacteriol 170,2296-2300.
16. Saier, M. H., Jr & Reizer, J. (1994). The bacterial phosphotransferase system: new frontiers 30 years later. Mol Microbiol 13, 755-764.
17. Saier, M. H., Jr, Young, W. S., III & Roseman, S. (1971). Utilization and transport of hexoses by mutant strains of Salmonella typhimurium lacking enzyme I of the phosphoenolpyruvate-dependent phosphotransferase system. J Biol Chem 246, 5838-5840.
18. Saier, M. H., Jr, Bromberg, F. G. & Roseman, S. (1973). Characterization of constitutive galactose permease mutants in Salmonella typhimurium. J Bacteriol 113, 512-514.
19. Saier, M. H., Jr, Cox, D. F. & Moczydlowski, E. G. (1977a). Sugar phosphate : sugar transphosphorylation coupled to exchange group translocation catalyzed by the Enzyme II complexes of the phosphoenolpyruvate : sugar phosphotransferase system in membrane vesicles of Escherichia coli. J Biol Chem 252, 8908-8916.
20. Saier, M. H., Jr, Feucht, B. U. & Mora, W. K. (1977b). Sugar phosphate : sugar transphosphorylation and exchange group translocation catalyzed by the Enzyme II complexes of the bacterial phosphoenolpyruvate: sugar phosphotransferase system. J Biol Chem 252, 8899-8907.
21. Saier, M. H., Jr, Newman, M. J. & Rephaeli, A. W. (1977c). Properties of a phosphoenolpyruvate : mannitol phosphotransferase system in Spirochaeta aurantia. J Biol Chem 252, 8890-8898.
22. Saier, M. H., Jr, Yamada, M., Suda, K., Erni, B., Rak, B., Lengeler, J., Stewart, G. C., Waygood, E. B. & Rapoport, G. (1988). Bacterial proteins with N-terminal leader sequences resembling mitochondrial targeting sequences of eukaryotes. Biochemie 70, 1743-1748.
23. Saier, M. H., Jr, Schnierow, B., Yamada, Y. & Daniels, G. A. (1989a). Structures, evolution and membrane insertion of the integral membrane permease proteins of the bacterial phosphotransferase system. In Highlights of Modern Biochemistry, vol. 1, pp. 771-780. Edited by A. Kotyk, J. Skoda, V. Paces & V. Kostk. Zeist: VSP International Science.
24. Saier, M. H., Jr, Werner, P. & Müller, M. (1989b). Insertion of proteins into bacterial membranes: mechanism, characteristics and comparisons with the eukaryotic process. Microbiol Rev 53, 333-366.
25. Sproul, A. A., Lambourne, L. T., Jean-Jacques, D. J. & Kornberg, H. L. (2001). Genetic control of manno(fructo)kinase activity in Escherichia coli. Proc Natl Acad Sci U S A 98, 15257-15259.
26. Tamm, L. K., Tomich, J. M. & Saier, M. H., Jr (1989). Membrane incorporation and induction of secondary structure of synthetic peptides corresponding to the N-terminal signal sequences of the glucitol and mannitol permeases of Escherichia coli. J Biol Chem 264, 2587-2592.
27. Tanaka, Y., Kimata, K. & Aiba, H. (2000). A novel regulatory role of glucose transporter of Escherichia coli: membrane sequestration of a global repressor Mlc. EMBO J 19, 5344-5352.
28. Yamada, Y., Chang, Y.-Y., Daniels, G. A., Wu, L.-F., Tomich, J. M., Yamada, M. & Saier, M. H., Jr (1991). Insertion of the mannitol permease into the membrane of Escherichia coli. Possible involvement of an N-terminal amphiphilic sequence. J Biol Chem 266, 17863-17871.
29. Glc and induction behaviour of the ptsG gene. J Bacteriol 182, 4443-4452.