Indinavir-induced thrombocytopenia

AIDS Patient Care and STDs

Volumn 17, Issue 3, 2003, Pages 103-104

  Camino, Nuria ^a   Núñez, Marina ^a   Blanco, Francisco ^a   González Requena, Daniel ^a   González Lahoz, Juan ^a   Soriano, Vincent ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DIDANOSINE; IMMUNOGLOBULIN; INDINAVIR; LAMIVUDINE; NEVIRAPINE; RITONAVIR; STAVUDINE; STEROID;

ADULT; ARTICLE; CASE REPORT; DISEASE COURSE; EPISTAXIS; GINGIVA BLEEDING; HEMATURIA; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; MALE; PURPURA; THROMBOCYTE COUNT; THROMBOCYTOPENIA; VIRUS LOAD;

EID: 0037351337     PISSN: 10872914     EISSN: None     Source Type: Journal    
DOI: 10.1089/108729103763807918     Document Type: Article

References (7)

1. Bonfanti P, Valsecchi L, Parazzini F, et al. Incidence of adverse reactions in HIV patients treated with protease inhibitors: a cohort study. J AIDS 2000;23:236-245.
2. Zucker S, Qin X, Rouster S, et al. Mechanisms of indinavir-induced hyperbilirubinemia. Proc Natl Acad Sci USA 2001;98:12671-12676.
3. Pechere M, Samii K, Hirschel B. HIV related thrombocytopenia. N Engl J Med 1993;328:1785-1786.
4. Nardi M, Tomhinson S, Greco M, Karpatkin S. Complement-independent, peroxide-induced antibody lysis of platelets in HIV-1-related immune thrombocytopenia. Cell 2001;106:551-561.
5. Stein D, Dunn H, Drusano G. Acute thrombocytopenia secondary to the administration of the peptidomimetic HIV protease inhibitor MK-639 (L735524). AIDS 1996;10:678-680.
6. Durand J. Indinavir and thrombocytopenia. AIDS 1999;13:148-149.
7. Casado J, Moreno A, Sabido R, et al. A clinical study of the combination of 100 mg ritonavir plus 800 mg indinavir as salvage therapy: Influence of increased plasma drug levels in the rate of response. HIV Clin Trials 2000;1:13-19.