Low blood selenium concentrations in schizophrenic patients on clozapine

British Journal of Clinical Pharmacology

Volumn 55, Issue 3, 2003, Pages 307-309

  Vaddadi, K S ^a   Soosai, E ^b   Vaddadi, G ^c  

^a MONASH UNIVERSITY   (Australia)

^b Clayton Comm Mental Health Service   (Australia)

^c AUSTIN HEALTH   (Australia)

Author keywords

Cardiomyopathy; Clozapine; Myocarditis; Schizophrenia; Selenium

Indexed keywords

CLOZAPINE; SELENIUM;

ADULT; AGRANULOCYTOSIS; ARTICLE; BLOOD SAMPLING; CARDIOMYOPATHY; CATECHOLAMINE METABOLISM; DIETARY INTAKE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MYOCARDITIS; OXIDATIVE STRESS; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; SCHIZOPHRENIA; SELENIUM DEFICIENCY; TRACE METAL BLOOD LEVEL;

ADULT; ANTIPSYCHOTIC AGENTS; CLOZAPINE; ERYTHROCYTES; FEMALE; HUMANS; MALE; MOOD DISORDERS; SCHIZOPHRENIA; SELENIUM; SEROTONIN ANTAGONISTS;

EID: 0037349229     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2003.01773.x     Document Type: Article

References (12)

1. Rayman M. The importance of selenium to human health. Lancet 2000; 356: 233-240.
2. Rayman MP. The argument for increasing selenium intake. Proc Nutr Soc 2002; 61: 203-215.
3. Chen X, Yang G, Chen J, Chen X, Wen Z, Ge K. Studies on the relation of selenium and Keshan disease. Biol Trace Element Res 1980; 2: 91-107.
4. Keshan Disease Research Group of the Chinese Academy of Medical Sciences. Observations on effect of sodium selenite in prevention of Keshan disease. Chin Med J (Engl) 1979; 92: 471-476.
5. Beck MA, Shi Q, Morris VC, Levander OA. Rapid genomic evolution of a non-virulent coxsackie virus B3 in selenium-deficient mice results in selection of identical virulent isolates. Nat Med 1995; 1: 433-436.
6. Killian JG, Kerr K, Lawrence C, Celermajer DS. Myocarditis and cardiomyopathy associated with clozapine. Lancet 1999; 354: 1841-1845.
7. Grenade LL, Graham D, Trontell A. Myocarditis and cardiomyopathy associated with clozapine use in the United States. N Engl J Med, 2001; 345: 224-225.
8. Linday LA, Pippenger CE, Howard A, Lieberman JA. Free radical scavenging enzyme activity and related trace metals in clozapine-induced agranulocytosis: a pilot study. J Clin Psychopharmacol 1995; 15: 353-360.
9. Jacobson BE, Lockitch G. Direct determination of selenium in serum by graphite-furnace atomic absorption spectrometry with deuterium background correction and a reduced palladium modifier: age-specific reference ranges. Clin Chem 1988; 34: 709-714.
10. Xie B, Zhou JF, Lu Q, Li CJ, Chen P. Oxidative stress in patients with acute coxsackie virus myocarditis. Biomed Environ Sci 2002; 15: 48-57.
11. Beck MA, Handy J, Levander OA. The role of oxidative stress in viral infections. Ann N Y Acad Sci 2000; 917: 906-912.
12. Smythies J. Role of free radicals in the brain in health and disease in relation to synaptic plasticity. In Free Radicals in Brain Pathology, eds Poly G, Cadenas E, Packer L. New York: Marcel Dekker, Inc., 2000; 1-16.