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Volumn 145, Issue 3, 2003, Pages 418-423

Preventing stroke in patients with atrial fibrillation: Current treatments and new concepts

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; ANTIVITAMIN K; CLOPIDOGREL; DIPYRIDAMOLE; PLACEBO; THROMBIN INHIBITOR; WARFARIN; XIMELAGATRAN;

EID: 0037348936     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1067/mhj.2003.84     Document Type: Review
Times cited : (34)

References (67)
  • 1
    • 0025214929 scopus 로고
    • Prevalence of cardiovascular disease and diabetes mellitus in residents of Rochester Minnesota
    • Phillips SJ, Whisnant JP, O'Fallon WM, Frye RL. Prevalence of cardiovascular disease and diabetes mellitus in residents of Rochester Minnesota. Mayo Clin Proc 1990;65:344-59.
    • (1990) Mayo Clin Proc , vol.65 , pp. 344-359
    • Phillips, S.J.1    Whisnant, J.P.2    O'Fallon, W.M.3    Frye, R.L.4
  • 2
    • 0003406415 scopus 로고    scopus 로고
    • Dallas, Tex: American Heart Association
    • American Heart Association 1998. Heart and stroke statistical update. Dallas, Tex: American Heart Association; 1997.
    • (1997) Heart and Stroke Statistical Update
  • 3
    • 0025779484 scopus 로고
    • Atrial fibrillation as an independent risk factor for stroke: The Framingham Study
    • Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:983-8.
    • (1991) Stroke , vol.22 , pp. 983-988
    • Wolf, P.A.1    Abbott, R.D.2    Kannel, W.B.3
  • 4
    • 0023625745 scopus 로고
    • Atrial fibrillation: A major contributor to stroke in the elderly: The Framingham Study
    • Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation: a major contributor to stroke in the elderly: the Framingham Study. Arch Intern Med 1987;147:1561-4.
    • (1987) Arch Intern Med , vol.147 , pp. 1561-1564
    • Wolf, P.A.1    Abbott, R.D.2    Kannel, W.B.3
  • 5
    • 0034012452 scopus 로고    scopus 로고
    • Atrial fibrillation and the use of warfarin in patients admitted to an acute stroke unit
    • Leckey R, Aguilar EG, Phillips SJ. Atrial fibrillation and the use of warfarin in patients admitted to an acute stroke unit. Can J Cardiol 2000;16:481-5.
    • (2000) Can J Cardiol , vol.16 , pp. 481-485
    • Leckey, R.1    Aguilar, E.G.2    Phillips, S.J.3
  • 6
    • 0025814587 scopus 로고
    • Canadian Atrial Fibrillation Anticoagulation (CAFA) Study
    • Connolly SJ, Laupacis A, Gent M, et al. Canadian Atrial Fibrillation Anticoagulation (CAFA) Study. J Am Coll Cardiol 1991;18:349-55.
    • (1991) J Am Coll Cardiol , vol.18 , pp. 349-355
    • Connolly, S.J.1    Laupacis, A.2    Gent, M.3
  • 7
    • 0024543543 scopus 로고
    • Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation: The Copenhagen AFASAK Study
    • Petersen P, Boysen G, Godtfredsen J, et al. Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation: the Copenhagen AFASAK Study. Lancet 1989;1:175-9.
    • (1989) Lancet , vol.1 , pp. 175-179
    • Petersen, P.1    Boysen, G.2    Godtfredsen, J.3
  • 8
    • 0025914693 scopus 로고
    • Stroke Prevention in Atrial Fibrillation Study: Final results
    • Stroke Prevention in Atrial Fibrillation Investigators. Stroke Prevention in Atrial Fibrillation Study: final results. Circulation 1991;84:527-39.
    • (1991) Circulation , vol.84 , pp. 527-539
  • 9
    • 0025241137 scopus 로고
    • The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation
    • The Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators. The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation. N Engl J Med 1990;323:1505-11.
    • (1990) N Engl J Med , vol.323 , pp. 1505-1511
  • 10
    • 0026478818 scopus 로고
    • Warfarin in the prevention of stroke associated with nonrheumatic atrial fibrillation
    • Ezekowitz MD, Bridgers SL, James KE, et al. Warfarin in the prevention of stroke associated with nonrheumatic atrial fibrillation. N Engl J Med 1992;327:1406-12.
    • (1992) N Engl J Med , vol.327 , pp. 1406-1412
    • Ezekowitz, M.D.1    Bridgers, S.L.2    James, K.E.3
  • 11
    • 0028244264 scopus 로고
    • Risk factors for stroke and efficacy of antithrombotic therapy in Atrial Fibrillation
    • Atrial Fibrillation Investigators. Risk factors for stroke and efficacy of antithrombotic therapy in Atrial Fibrillation. Arch Intern Med 1994;154:1449-57.
    • (1994) Arch Intern Med , vol.154 , pp. 1449-1457
  • 12
    • 0027505093 scopus 로고
    • Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke
    • EAFT (European Atrial Fibrillation Trial) Study Group. Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke. Lancet 1993;342:1255-62.
    • (1993) Lancet , vol.342 , pp. 1255-1262
  • 13
    • 0030297319 scopus 로고    scopus 로고
    • European Stroke Prevention Study 2: Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke
    • Diener HC, Cunha L, Forbes C, et al. European Stroke Prevention Study 2: dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci 1996;143:1-13.
    • (1996) J Neurol Sci , vol.143 , pp. 1-13
    • Diener, H.C.1    Cunha, L.2    Forbes, C.3
  • 15
    • 0032780250 scopus 로고    scopus 로고
    • Alternate day dosing of aspirin in atrial fibrillation
    • Posada IS, Barriates V. Alternate day dosing of aspirin in atrial fibrillation. Am Heart J 1999;138:137-43.
    • (1999) Am Heart J , vol.138 , pp. 137-143
    • Posada, I.S.1    Barriates, V.2
  • 16
    • 0000988332 scopus 로고    scopus 로고
    • Antiplatelet therapy to prevent stroke: Risk of brain hemorrhage and efficacy of aspirin
    • Diener HC, Lowenthal A. Antiplatelet therapy to prevent stroke: risk of brain hemorrhage and efficacy of aspirin. J Neurol Sci 1997;153:112.
    • (1997) J Neurol Sci , vol.153 , pp. 112
    • Diener, H.C.1    Lowenthal, A.2
  • 17
    • 0033527355 scopus 로고    scopus 로고
    • Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: A meta-analysis
    • Hart RG, Benavente O, McBride R, et al. Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis. Ann Intern Med 1999;131:492-501.
    • (1999) Ann Intern Med , vol.131 , pp. 492-501
    • Hart, R.G.1    Benavente, O.2    McBride, R.3
  • 18
    • 0002416628 scopus 로고    scopus 로고
    • Primary prevention of arterial thromboembolism in patients with non-rheumatic atrial fibrillotion in general practice
    • Hellemons BS, Langenberg M, Lodder J, et al. Primary prevention of arterial thromboembolism in patients with non-rheumatic atrial fibrillotion in general practice. Cerebrovasc Dis 1997;7(4 Suppl):11.
    • (1997) Cerebrovasc Dis , vol.7 , Issue.4 SUPPL. , pp. 11
    • Hellemons, B.S.1    Langenberg, M.2    Lodder, J.3
  • 19
    • 2942696888 scopus 로고
    • Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation: Stroke Prevention in Atrial Fibrillation II Study
    • Stroke Prevention in Atrial Fibrillation Investigators. Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation: Stroke Prevention in Atrial Fibrillation II Study. Lancet 1994;343:687-91.
    • (1994) Lancet , vol.343 , pp. 687-691
  • 20
    • 0031852543 scopus 로고    scopus 로고
    • Fixed minidose warfarin and aspirin alone and in combination vs adjusted-dose warfarin for stroke prevention in atrial fibrillation: Second Copenhagen Atrial Fibrillation, Aspirin, and Anticoagulation Study
    • Gullov AL, Koefoed BG, Petersen P, et al. Fixed minidose warfarin and aspirin alone and in combination vs adjusted-dose warfarin for stroke prevention in atrial fibrillation: Second Copenhagen Atrial Fibrillation, Aspirin, and Anticoagulation Study. Arch Intern Med 1998;158:1513-21.
    • (1998) Arch Intern Med , vol.158 , pp. 1513-1521
    • Gullov, A.L.1    Koefoed, B.G.2    Petersen, P.3
  • 21
    • 8244245263 scopus 로고    scopus 로고
    • Indobufen versus warfarin in the secondary prevention of major vascular events in non-rheumatic atrial fibrillation
    • Morocutti C, Amabile G, Fattaposta F, et al. Indobufen versus warfarin in the secondary prevention of major vascular events in non-rheumatic atrial fibrillation. Stroke 1997;28:1015-21.
    • (1997) Stroke , vol.28 , pp. 1015-1021
    • Morocutti, C.1    Amabile, G.2    Fattaposta, F.3
  • 22
    • 0035835397 scopus 로고    scopus 로고
    • Systematic review of long term anticoagulation or antiplatelet treatment in patients with non-rheumatic atrial fibrillation
    • Taylor FC, Cohen H, Ebrahim S. Systematic review of long term anticoagulation or antiplatelet treatment in patients with non-rheumatic atrial fibrillation. BMJ 2001;322:321-6.
    • (2001) BMJ , vol.322 , pp. 321-326
    • Taylor, F.C.1    Cohen, H.2    Ebrahim, S.3
  • 23
    • 9544248668 scopus 로고    scopus 로고
    • Adjusted dose warfarin versus low intensity fixed dose warfarin plus aspirin for high risk patients with atrial fibrillation: The Stroke Prevention in Atrial Fibrillation III randomized clinical trial
    • Stroke Prevention in Atrial Fibrillation Investigators. Adjusted dose warfarin versus low intensity fixed dose warfarin plus aspirin for high risk patients with atrial fibrillation: the Stroke Prevention in Atrial Fibrillation III randomized clinical trial. Lancet 1996;279:633-8.
    • (1996) Lancet , vol.279 , pp. 633-638
  • 24
    • 0029761926 scopus 로고    scopus 로고
    • Antithrombotic therapy in atrial fibrillation: CCS consensus conference on atrial fibrillation
    • Connolly SJ, Turpie AGG. Antithrombotic therapy in atrial fibrillation: CCS consensus conference on atrial fibrillation. Can J Cardiol 1996;12:17-20A.
    • (1996) Can J Cardiol , vol.12
    • Connolly, S.J.1    Turpie, A.G.G.2
  • 25
    • 0034814620 scopus 로고    scopus 로고
    • ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: Executive summary
    • Fuster V, Ryden LE, Asinger RW, et al. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: executive summary. J Am Coll Cardiol 2002;38:1231-65.
    • (2002) J Am Coll Cardiol , vol.38 , pp. 1231-1265
    • Fuster, V.1    Ryden, L.E.2    Asinger, R.W.3
  • 26
    • 0035128599 scopus 로고    scopus 로고
    • Antithrombotic therapy in atrial fibrillation
    • Albers GW, Dalen JE, Laupacis A, et al. Antithrombotic therapy in atrial fibrillation. Chest 2001;119:194-206S.
    • (2001) Chest , vol.119
    • Albers, G.W.1    Dalen, J.E.2    Laupacis, A.3
  • 27
    • 0031729679 scopus 로고    scopus 로고
    • Oral anticoagulants. Mechanism of action, clinical effectiveness, and optimal therapeutic range
    • Hirsh J, Dalen JE, Anderson DR, et al. Oral anticoagulants. Mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest 1998;114:445-69S.
    • (1998) Chest , vol.114
    • Hirsh, J.1    Dalen, J.E.2    Anderson, D.R.3
  • 28
    • 0029741822 scopus 로고    scopus 로고
    • An analysis of the lowest effective intensity of prophylactic anticoagulation for patients with nonrheumatic atrial fibrillation
    • Hylek EM, Skates SJ, Sheehan MA, et al. An analysis of the lowest effective intensity of prophylactic anticoagulation for patients with nonrheumatic atrial fibrillation. N Engl J Med 1996;335:540-6.
    • (1996) N Engl J Med , vol.335 , pp. 540-546
    • Hylek, E.M.1    Skates, S.J.2    Sheehan, M.A.3
  • 29
    • 0028343127 scopus 로고
    • Risk factors for intracranial hemorrhage in outpatients taking warfarin
    • Hylek EM, Singer DE. Risk factors for intracranial hemorrhage in outpatients taking warfarin. Ann Intern Med 1994;120:897-902.
    • (1994) Ann Intern Med , vol.120 , pp. 897-902
    • Hylek, E.M.1    Singer, D.E.2
  • 30
    • 0029851556 scopus 로고    scopus 로고
    • National patterns of warfarin use in atrial fibrillation
    • Stafford RS, Singer DE. National patterns of warfarin use in atrial fibrillation. Arch Intern Med 1996;156:2537-41.
    • (1996) Arch Intern Med , vol.156 , pp. 2537-2541
    • Stafford, R.S.1    Singer, D.E.2
  • 31
    • 0030024925 scopus 로고    scopus 로고
    • Physician practices regarding anticoagulation and cardioversion of atrial fibrillation
    • Schlicht JR, Davis RC, Naqi K, et al. Physician practices regarding anticoagulation and cardioversion of atrial fibrillation. Arch Intern Med 1996;156:290-4.
    • (1996) Arch Intern Med , vol.156 , pp. 290-294
    • Schlicht, J.R.1    Davis, R.C.2    Naqi, K.3
  • 32
    • 10544255348 scopus 로고    scopus 로고
    • Status of antithrombotic therapy for patients with atrial fibrillation in university hospitals
    • Albers GW, Yim JM, Belew KM, et al. Status of antithrombotic therapy for patients with atrial fibrillation in university hospitals. Arch Intern Med 1996;156:2311-6.
    • (1996) Arch Intern Med , vol.156 , pp. 2311-2316
    • Albers, G.W.1    Yim, J.M.2    Belew, K.M.3
  • 33
    • 0031470274 scopus 로고    scopus 로고
    • Warfarin use among patients with atrial fibrillation
    • Brass LM, Krumholz HM, Scinto JM, et al. Warfarin use among patients with atrial fibrillation. Stroke 1997;28:2382-9.
    • (1997) Stroke , vol.28 , pp. 2382-2389
    • Brass, L.M.1    Krumholz, H.M.2    Scinto, J.M.3
  • 34
    • 0031053980 scopus 로고    scopus 로고
    • Is warfarin underused in the treatment of elderly persons with atrial fibrillation?
    • Whittle J, Wickenheiser L, Venditti LN. Is warfarin underused in the treatment of elderly persons with atrial fibrillation? Arch Intern Med 1997;157:441-5.
    • (1997) Arch Intern Med , vol.157 , pp. 441-445
    • Whittle, J.1    Wickenheiser, L.2    Venditti, L.N.3
  • 35
    • 0031015882 scopus 로고    scopus 로고
    • Thromboembolism prophylaxis in chronic atrial fibrillation: Practice patterns in community and tertiary-care hospitals
    • Munschauer FE, Priore RL, Hens M, et al. Thromboembolism prophylaxis in chronic atrial fibrillation: practice patterns in community and tertiary-care hospitals. Stroke 1997;28:72-6.
    • (1997) Stroke , vol.28 , pp. 72-76
    • Munschauer, F.E.1    Priore, R.L.2    Hens, M.3
  • 36
    • 2942533675 scopus 로고    scopus 로고
    • Thromboembolic prophylaxis in 3575 hospitalized patients with atrial fibrillation
    • The Clinical Quality Improvement Network (CQIN) Investigators. Thromboembolic prophylaxis in 3575 hospitalized patients with atrial fibrillation. Can J Cardiol 1998;14:695-702.
    • (1998) Can J Cardiol , vol.14 , pp. 695-702
  • 37
    • 0032505605 scopus 로고    scopus 로고
    • Prevalence of atrial fibrillation and eligibility for anticoagulants in the community
    • Sudlow M, Thomson R, Thwaites B, et al. Prevalence of atrial fibrillation and eligibility for anticoagulants in the community. Lancet 1998;352:1167-71.
    • (1998) Lancet , vol.352 , pp. 1167-1171
    • Sudlow, M.1    Thomson, R.2    Thwaites, B.3
  • 38
    • 0033063754 scopus 로고    scopus 로고
    • Factors associated with ischemic stroke during aspirin therapy in atrial fibrillation
    • Hart RG, Pearce LA, McBride R, et al. Factors associated with ischemic stroke during aspirin therapy in atrial fibrillation. Stroke 1999;30:1223-9.
    • (1999) Stroke , vol.30 , pp. 1223-1229
    • Hart, R.G.1    Pearce, L.A.2    McBride, R.3
  • 39
    • 0033593072 scopus 로고    scopus 로고
    • Warfarin use among ambulatory patients with non-valvular atrial fibrillation: The anticoagulation and risk factor in atrial fibrillation (ATRIA) study
    • Go AS, Hylek EM, Borowsky LH, et al. Warfarin use among ambulatory patients with non-valvular atrial fibrillation: the anticoagulation and risk factor in atrial fibrillation (ATRIA) study. Ann Intern Med 1999;131:927-34.
    • (1999) Ann Intern Med , vol.131 , pp. 927-934
    • Go, A.S.1    Hylek, E.M.2    Borowsky, L.H.3
  • 40
    • 0033040208 scopus 로고    scopus 로고
    • Risk assessment and anticoagulation for primary stroke prevention in atrial fibrillation
    • Kalra L, Perez I, Melbourn A. Risk assessment and anticoagulation for primary stroke prevention in atrial fibrillation. Stroke 1999;30:1218-22.
    • (1999) Stroke , vol.30 , pp. 1218-1222
    • Kalra, L.1    Perez, I.2    Melbourn, A.3
  • 41
    • 0032723886 scopus 로고    scopus 로고
    • Use of antithrombotic measures for stroke prevention in atrial fibrillation
    • Perez I, Melbourn A, Kalra L. Use of antithrombotic measures for stroke prevention in atrial fibrillation. Heart 1999;82:570-4.
    • (1999) Heart , vol.82 , pp. 570-574
    • Perez, I.1    Melbourn, A.2    Kalra, L.3
  • 42
    • 0034627893 scopus 로고    scopus 로고
    • Why do patients with atrial fibrillation not receive warfarin?
    • Bungard TJ, Ghali WA, Teo KK, et al. Why do patients with atrial fibrillation not receive warfarin? Arch Intern Med 2000;160:1295-302.
    • (2000) Arch Intern Med , vol.160 , pp. 1295-1302
    • Bungard, T.J.1    Ghali, W.A.2    Teo, K.K.3
  • 43
    • 0033562553 scopus 로고    scopus 로고
    • Implementing evidence based medicine in general practice: Audit and qualitative study of antithrombotic treatment for atrial fibrillation
    • Hewitt A, Armstrong D. Implementing evidence based medicine in general practice: audit and qualitative study of antithrombotic treatment for atrial fibrillation. BMJ 1999;318:1324-8.
    • (1999) BMJ , vol.318 , pp. 1324-1328
    • Hewitt, A.1    Armstrong, D.2
  • 44
    • 0029840614 scopus 로고    scopus 로고
    • The effect of stroke and stroke prophylaxis with aspirin or warfarin on quality of life
    • Gage BF, Cardinalli AB, Owens DK. The effect of stroke and stroke prophylaxis with aspirin or warfarin on quality of life. Arch Intern Med 1996;156:1829-36.
    • (1996) Arch Intern Med , vol.156 , pp. 1829-1836
    • Gage, B.F.1    Cardinalli, A.B.2    Owens, D.K.3
  • 45
    • 0028120906 scopus 로고
    • Collaborative overview of randomized trials of antiplatelet therapy: 1: Prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients
    • Antiplatelet Trialists' Collaboration. Collaborative overview of randomized trials of antiplatelet therapy: 1: prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ 1994;308:81-106.
    • (1994) BMJ , vol.308 , pp. 81-106
  • 46
    • 0034655567 scopus 로고    scopus 로고
    • Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial
    • Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. Lancet 2000;335:1295-302.
    • (2000) Lancet , vol.335 , pp. 1295-1302
  • 47
    • 0003181571 scopus 로고    scopus 로고
    • European Stroke Prevention Study II: Efficacy and safety data
    • Dieneer HC, Forbes C, Riekkinen PJ, et al. European Stroke Prevention Study II: efficacy and safety data. J Neurol Sci 1997;151:S27-37.
    • (1997) J Neurol Sci , vol.151
    • Dieneer, H.C.1    Forbes, C.2    Riekkinen, P.J.3
  • 48
  • 49
    • 0031760604 scopus 로고    scopus 로고
    • Platelet-active drugs: The relationships among dose effectiveness, and side effects
    • Patrono C, Coller B, Dalen JE, et al. Platelet-active drugs: the relationships among dose effectiveness, and side effects. Chest 1998;114:470-88S.
    • (1998) Chest , vol.114
    • Patrono, C.1    Coller, B.2    Dalen, J.E.3
  • 50
    • 0032481092 scopus 로고    scopus 로고
    • A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting
    • Leon MB, Baim DS, Popma JJ, et al. A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. N Engl J Med 1998;339:1665-71.
    • (1998) N Engl J Med , vol.339 , pp. 1665-1671
    • Leon, M.B.1    Baim, D.S.2    Popma, J.J.3
  • 51
    • 7844220998 scopus 로고    scopus 로고
    • Randomized multicenter comparison of conventional anticoagulation versus antiplatelet therapy in unplanned and elective coronary stenting: The Full Anticoagulation Versus Aspirin and Ticlopidine (FANTASTIC) Study
    • Bertrand ME, Legrand V, Boland J, et al. Randomized multicenter comparison of conventional anticoagulation versus antiplatelet therapy in unplanned and elective coronary stenting: the Full Anticoagulation Versus Aspirin and Ticlopidine (FANTASTIC) Study. Circulation 1998;98:1597-603.
    • (1998) Circulation , vol.98 , pp. 1597-1603
    • Bertrand, M.E.1    Legrand, V.2    Boland, J.3
  • 52
    • 0032542028 scopus 로고    scopus 로고
    • Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high-risk patients: The Multicenter Aspirin and Ticlopidine Trial after Intracoronary Stenting (MATIIS)
    • Urban P, Macaya C, Rupprecht H-J, et al. Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high-risk patients: the Multicenter Aspirin and Ticlopidine Trial after Intracoronary Stenting (MATIIS). Circulation 1998;98:2126-32.
    • (1998) Circulation , vol.98 , pp. 2126-2132
    • Urban, P.1    Macaya, C.2    Rupprecht, H.-J.3
  • 53
    • 9244251971 scopus 로고    scopus 로고
    • A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents
    • Schomig A, Neumann F-J, Kastrati A, et al. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents. N Engl J Med 1996;334:1084-9.
    • (1996) N Engl J Med , vol.334 , pp. 1084-1089
    • Schomig, A.1    Neumann, F.-J.2    Kastrati, A.3
  • 54
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • The Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of Clopidogrel in Addition to Aspirin in Patients With Acute Coronary Syndromes without ST-Segment Elevation. N Engl J Med 2001;345:494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
  • 55
    • 0032723885 scopus 로고    scopus 로고
    • Left atrial appendage: Structure, function, and the role in thromboembolism
    • Al-Saady NM, Obel OA, Camm AJ. Left atrial appendage: structure, function, and the role in thromboembolism. Heart 1999;82:547-54.
    • (1999) Heart , vol.82 , pp. 547-554
    • Al-Saady, N.M.1    Obel, O.A.2    Camm, A.J.3
  • 56
    • 0028964650 scopus 로고
    • Transesophageal echocardiography facilitated early cardioversion from atrial fibrillation using short term anticoagulation: Final results of a prospective 4.5 year study
    • Manning WJ, Silverman DI, Katz SE, et al. Transesophageal echocardiography facilitated early cardioversion from atrial fibrillation using short term anticoagulation: final results of a prospective 4.5 year study. J Am Coll Cardiol 1995;25:1354-61.
    • (1995) J Am Coll Cardiol , vol.25 , pp. 1354-1361
    • Manning, W.J.1    Silverman, D.I.2    Katz, S.E.3
  • 57
    • 0030051404 scopus 로고    scopus 로고
    • Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation
    • Blackshear JL, Odell JA. Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation. Ann Thorac Surg 1996;61:565-9.
    • (1996) Ann Thorac Surg , vol.61 , pp. 565-569
    • Blackshear, J.L.1    Odell, J.A.2
  • 58
    • 0037161359 scopus 로고    scopus 로고
    • Percutaneous left atrial appendage transcatheter occlusion to prevent stroke in high-risk patients with atrial fibrillation: Early clinical experience
    • Sievert H, Lesh MD, Trepels T, et al. Percutaneous left atrial appendage transcatheter occlusion to prevent stroke in high-risk patients with atrial fibrillation: early clinical experience. Circulation 2002;105:1887-9.
    • (2002) Circulation , vol.105 , pp. 1887-1889
    • Sievert, H.1    Lesh, M.D.2    Trepels, T.3
  • 59
    • 0035868256 scopus 로고    scopus 로고
    • The effects of oral and intravenous direct thrombin inhibitors on the size of photochemically induced cortical infarction in rats
    • Mukilski A, Elg M, Gustafsson D. The effects of oral and intravenous direct thrombin inhibitors on the size of photochemically induced cortical infarction in rats. Thromb Res 2001;101:477-82.
    • (2001) Thromb Res , vol.101 , pp. 477-482
    • Mukilski, A.1    Elg, M.2    Gustafsson, D.3
  • 60
    • 0035251672 scopus 로고    scopus 로고
    • The direct thrombin inhibitor melagatron and its oral prodrug H 376/95: Intestinal absorbtion properties, biochemical and pharmacodynamic effects
    • Gustafsson D, Nystrom J, Carlsson S, et al. The direct thrombin inhibitor melagatron and its oral prodrug H 376/95: intestinal absorbtion properties, biochemical and pharmacodynamic effects. Thromb Res 2001;101:171-81.
    • (2001) Thromb Res , vol.101 , pp. 171-181
    • Gustafsson, D.1    Nystrom, J.2    Carlsson, S.3
  • 61
    • 85112378502 scopus 로고    scopus 로고
    • Pharmbcodynamics and pharmacokinetics of H 376/95 after oral dosing in healthy male subjects of different ethic origin
    • Johansson L, Eriksson UG, Frison L, et al. Pharmbcodynamics and pharmacokinetics of H 376/95 after oral dosing in healthy male subjects of different ethic origin. Blood 2000;96:56A.
    • (2000) Blood , vol.96
    • Johansson, L.1    Eriksson, U.G.2    Frison, L.3
  • 62
    • 85112368229 scopus 로고    scopus 로고
    • Pharmacokinetics of H 376/95 in young and healthy subjects
    • Johansson L, Eriksson UG, Frison L, et al. Pharmacokinetics of H 376/95 in young and healthy subjects. Blood 2000;96:57A.
    • (2000) Blood , vol.96
    • Johansson, L.1    Eriksson, U.G.2    Frison, L.3
  • 63
    • 33748536732 scopus 로고    scopus 로고
    • Pharmacokinetics of melagatron, the active form of the oral, direct thrombin inhibitor H 376/95, in orthopaedic surgery patients treated to prevent deep vein thrombosis and pulmonary embolism
    • Eriksson UG, Gustafsson D, Mandema J, et al. Pharmacokinetics of melagatron, the active form of the oral, direct thrombin inhibitor H 376/95, in orthopaedic surgery patients treated to prevent deep vein thrombosis and pulmonary embolism. Blood 2000;96:93B.
    • (2000) Blood , vol.96
    • Eriksson, U.G.1    Gustafsson, D.2    Mandema, J.3
  • 64
    • 0033135457 scopus 로고    scopus 로고
    • Antithrombotic effects and bleeding tlme of thrombin inhibitors and warfarin in the rat
    • Elg M, Gustafsson D, Carlsson S. Antithrombotic effects and bleeding tlme of thrombin inhibitors and warfarin in the rat. Thromb Res 1999;94:187-97.
    • (1999) Thromb Res , vol.94 , pp. 187-197
    • Elg, M.1    Gustafsson, D.2    Carlsson, S.3
  • 65
    • 85112354628 scopus 로고    scopus 로고
    • Prothrombin time assays are unsuitable for monitoring the effects of melagatron, the active form of the oral, direct thrombin inhibitor H 376/95
    • Mattsson C, Menschik-Lundin A. Prothrombin time assays are unsuitable for monitoring the effects of melagatron, the active form of the oral, direct thrombin inhibitor H 376/95. Blood 2000;96:98B.
    • (2000) Blood , vol.96
    • Mattsson, C.1    Menschik-Lundin, A.2
  • 66
    • 0002899269 scopus 로고    scopus 로고
    • Comparison of the oral direct thrombin inhibitor h 376/95 with enoxaparin as prophylaxis against venous thromboembolism after total knee replacement: A phase II dose-finding study
    • Heit JA, Colwell CW, Francis CW, et al. Comparison of the oral direct thrombin inhibitor h 376/95 with enoxaparin as prophylaxis against venous thromboembolism after total knee replacement: a phase II dose-finding study. Blood 1996;101:491A.
    • (1996) Blood , vol.101
    • Heit, J.A.1    Colwell, C.W.2    Francis, C.W.3
  • 67
    • 0002210177 scopus 로고    scopus 로고
    • First experience with the oral direct thrombin inhibitor H 376/95 compared to warfarin in patients with non-valvular atrial fibrillation (NVAF)
    • Petersen P. First experience with the oral direct thrombin inhibitor H 376/95 compared to warfarin in patients with non-valvular atrial fibrillation (NVAF). J Gen Intern Med 2001;16(1 Suppl):164.
    • (2001) J Gen Intern Med , vol.16 , Issue.1 SUPPL. , pp. 164
    • Petersen, P.1


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