5-HT mechanisms of median raphe nucleus in the conditioned freezing caused by light/foot-shock association

Physiology and Behavior

Volumn 78, Issue 3, 2003, Pages 471-477

  Avanzi, V ^a   Silva, R C B ^a   Macedo, C E ^a   Brandao M L ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

8 OH DPAT; Fear conditioning; Freezing; Median raphe nucleus; NMDA

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; N METHYL DEXTRO ASPARTIC ACID; SEROTONIN;

ANIMAL EXPERIMENT; ARTICLE; AUDITORY STIMULATION; CONDITIONING; CONTROLLED STUDY; FEAR; HISTOPATHOLOGY; LIGHT; MALE; MEDIAN RAPHE NUCLEUS; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; STIMULUS RESPONSE;

EID: 0037348862     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(03)00029-5     Document Type: Article

References (47)

1. Albinsson A., Andersson G., Andersson K., Vega-Matuszczyk J., Larsson K. The effects of lesions in the mesencephalic raphe systems on male rat sexual behavior and locomotor activity. Behav. Brain Res. 80:1996;57-63.
2. Andrade T.G.C.S., Graeff F.G. Effect of electrolytic and neurotoxic lesions of the median raphe nucleus on anxiety and stress. Pharmacol. Biochem. Behav. 70:2001;1-14.
3. 1A autoreceptors in the median raphe nucleus disrupts the contextual conditioning in rats. Behav. Brain Res. 126:2001;175-184.
4. Avanzi V., Castilho V.M., Andrade T.G.C., Brandão M.L. Regulation of contextual conditioning by the median raphe nucleus. Brain Res. 790:1998;178-184.
5. Azmitia E.C., Segal M. An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe. J. Comp. Neurol. 179:1978;641-668.
6. Blanchard D.C., Blanchard R.J. Innate and conditioned reactions to threat in rats with amygdaloid lesions. J. Comp. Physiol. Psychol. 81(2):1972;281-290.
7. 1A agonist gepirone: electrophysiological studies in the rat brain. Synapse. 1:1987;470-480.
8. Bobillier P., Petijean F., Salvert D., Ligier M., Seguin S. Differential projections of the nucleus raphe dorsalis and nucleus raphe centralis as revealed by autoradiography. Brain Res. 85:1975;205-210.
9. Bobillier P., Segin S., Petijean F., Salvery D., Touret M., Jouvet M. The raphe nuclei of the cat brainstem: a topographical atlas of their efferent projections as revealed by autoradiography. Brain Res. 113:1976;449-486.
10. Campeau S., Davis M. Involvement of the central nucleus and basolateral complex of the amygdala in fear conditioning measured with fear-potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli. J. Neurosci. 15:1995;2301-2311.
11. Chan K.-H., Morell J.R., Jarrard L.E., Davidson T.L. Reconsideration of the role of hippocampus in learned inhibition. Behav. Brain Res. 119:2001;111-130.
12. Corcoran K.A., Maren S. Hippocampal inactivation disrupts contextual retrieval of fear memory after extinction. J. Neurosci. 21(5):2001;1720-1726.
13. Davis M., Rainnie D., Cassell M. Neurotransmission in the rat amygdala related to fear and anxiety. Trends Neurosci. 17:1994;208-214.
14. Deakin J.W.F., Graeff F.G. 5-HT mechanisms of defense. J. Psychopharmacol. 5:1991;305-315.
15. Fanselow M.S. Contextual fear, gestalt memories, and the hippoccampus. Behav. Brain Res. 110:2000;73-81.
16. Fendt M., Fanselow M.S. The neuroanatomical and neurochemical basis of conditioned fear. Neurosci. Biobehav. Rev. 23:1999;743-760.
17. Geyer M.A., Puerto A., Dawsey W.J., Knapp S., Bullard W.P., Mandell A.J. Histologic and enzymatic studies of the mesolimbic and mesostriatal serotonergic pathways. Brain Res. 106:1976;241-256.
18. Goosens K.A., Maren S. Contextual and auditory fear conditioning are mediated by lateral, basal, and central amygdaloid nuclei in rats. Learn. Mem. 8(3):2001;148-155.
19. Graeff F.G., Silveira Filho G. Behavioral inhibition induced by electrical stimulation of the median raphe nucleus of the rat. Physiol. Behav. 71:1978;477-484.
20. Gray J.A. The septo-hippocampal system: anatomy. Gray J.A. The psychology of fear and stress. 1987;292-313 Cambridge Univ. Press, New York.
21. Gray J.A., McNaughton N. Fundamentals of the septo-hippocampal system. Gray J.A., McNaughton N. The neuropsychology of anxiety: an enquiry into the functions of septo-hippocampal system. 2nd ed. 2000;204-232 Oxford Univ. Press, Oxford.
22. 1A receptor antagonists with an SSRI in conditioned fear stress-induced freezing behavior. Pharmacol. Biochem. Behav. 58(2):1997;471-475.
23. Helmstetter F.J. The amygdala is essential for the expression of conditional hypoalgesia. Behav. Neurosci. 106:1992;518-528.
24. 1A agonist 8-OH-DPAT stimulates rat motor activity. Eur. J. Pharmacol. 160:1989;303-307.
25. Hillegaart V. Effects of application of 5-HT and 8-OH-DPAT into the dorsal and median raphe nuclei on motor activity in the rat. Physiol. Behav. 48:1990;43-148.
26. Hitchcock J.M., Davis M. Lesions of amygdala, but not the cerebellum or red nucleus, block conditioned fear as measured with the potentiated startle paradigm. Behav. Neurosci. 100:1986;11-22.
27. Inoue T., Hashimoto S., Tsuchia K., Izumi T., Ohmori T., Koyama T. Effect of citalopram, a selective serotonin reuptake inhibitor, on the acquisition of conditioned freezing. Eur. J. Pharmacol. 311:1996;1-6.
28. Kim J.J., Fanselow M.S. Modality-specific retrograde amnesia of fear. Science. 256:1992;675-677.
29. LeDoux J.E., Iwata J., Cicchetti P., Reis D.J. Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear. J. Neurosci. 8:1988;2517-2529.
30. LeDoux J.E. Emotion: Clues from the brain. Ann. Rev. Psychol. 46:1995;209-235.
31. Li X.B., Inoue T., Hashimoto S., Koyama T. Effect of chronic administration of flesinoxam and fluvoxamine on freezing behavior induced by conditioned fear. Eur. J. Pharmacol. 425:2001;43-50.
32. Maren S. Neurotoxic basolateral amygdala lesions impair learning and memory but not the performance of conditional fear in rats. J. Neurosci. 19(19):1999;8696-8703.
33. McKenna J.T., Vertes R.P. Collateral projections from the median raphe nucleus to the medial septum and hippocampus. Brain Res. Bull. 54(6):2001;619-630.
34. Melik E., Babar-Melik E., Ozgunen T., Binokay S. Median raphe nucleus mediates forming long-term but not short term contextual fear conditioning in rats. Behav. Brain Res. 112:2000;145-150.
35. Molliver M.E. Serotonergic neuronal systems: what their anatomic organization tells us about function. J. Clin. Pharmacol. 7:1987;3-23.
36. Morris R.G., Anderson E., Lynch G.S., Baudry M. Selective impairment of learning and blockade of log-term potentiation by an N-methyl-D-aspartate receptor agonist, AP5. Nature. 319:1986;774-776.
37. Nader K., Majidishad P., Amorapanth P., LeDoux J.E. Damage to lateral and central, but not other, amygdaloid nuclei prevents the acquisition of auditory fear conditioning. Learn. Mem. 8(3):2001;156-163.
38. Nieuwenhuys R. Chemoarchitecture of the brain. 1985;33-41 Springer-Verlag, Berlin.
39. Olton D.S., Becker J.T., Handelmann G.E. Hippocampus, space, and memory. Behav. Brain Sci. 2:1979;313-365.
40. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 3rd ed. 1997;Academic Press, New York.
41. Phillips R.G., LeDoux J.E. Differential contributions of amygdala and hippocampus to cued and contextual fear conditioning. Behav. Neurosci. 106:1992;274-285.
42. Phillips R.G., LeDoux J.E. Lesions of the dorsal hippocampal formation interfere with background but not foreground contextual fear conditioning. Learn. Mem. 1:1994;34-44.
43. Sananes C.B., Davis M. N-methyl-D-aspartate lesions of the lateral and basolateral nuclei of the amygdala block fear-potentiated startle and shock sensitization of startle. Behav. Neurosci. 106:1992;72-80.
44. Silva R.C.B., Cruz A.P.M., Landeira-Fernandez J., Avanzi V., Brandão M.L. Distinct contributions of median raphe nucleus to contextual fear conditioning and fear potentiated startle. Behav. Brain Res. 2002;. [submitted for publication].
45. 1A receptors in classical fear conditioning in C57BL/6J mice. J. Neurosci. 20(22):2000;8515-8527.
46. Wilensky A.E., Schafe G.E., LeDoux J.E. The amygdala modulates memory consolidation of fear-motivated inhibitory avoidance learning but not classical fear conditioning. J. Neurosci. 20(18):2000;7059-7066.
47. Wirtshafter D., Asin K.E. Evidence that electrolytic median raphe lesions increase locomotion but not exploration. Physiol. Behav. 28:1982;749-754.