On-line coupling of size exclusion and capillary zone electrophoresis via a reversed-phase C18 trapping column for the analysis of structurally related enkephalins in cerebrospinal fluid

Electrophoresis

Volumn 24, Issue 5, 2003, Pages 897-903

  Stroink, Thom ^a   Wiese, Gerard ^a   Teeuwsen, Jan ^a   Lingeman, Henk ^b   Waterval, Joop C M ^c   Bult, Auke ^a   de Jong, Gerhardus J ^a   Underberg, Willy J M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c NONE

Author keywords

Capillary zone electrophoresis; Cerebrospinal fluid; Multidimensional separation; Peptide; Size exclusion chromatography

Indexed keywords

ASSAYS; BRAIN; CAPILLARY ELECTROPHORESIS; CEREBROSPINAL FLUID; SIZE EXCLUSION CHROMATOGRAPHY;

BIOLOGICAL MATRIXES; CAPILLARY-ZONE ELECTROPHORESIS; CHROMATOGRAPHIC SEPARATIONS; EXCLUSION ZONES; MICRO-COLUMNS; MULTIDIMENSIONAL SEPARATIONS; ON-LINE COUPLING; REVERSED PHASE; SIZE EXCLUSION; SIZE-EXCLUSION CHROMATOGRAPHY;

PEPTIDES;

ACETONITRILE; ENKEPHALIN DERIVATIVE; ENKEPHALIN[2 ALANINE 5 LEUCINE]; IMIPRAMINE; LEUCINE ENKEPHALIN; LEUCINE ENKEPHALIN DERIVATIVE; METENKEPHALIN; METENKEPHALIN DERIVATIVE; METENKEPHALIN[2 ALANINE]; PEPTIDASE; PEPTIDE DERIVATIVE;

ACCURACY; ANALYTIC METHOD; ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DEGRADATION; DRUG DETERMINATION; DRUG STRUCTURE; ELUTION; FEASIBILITY STUDY; GEL PERMEATION CHROMATOGRAPHY; LINEAR SYSTEM; ONLINE SYSTEM; PROTEIN CEREBROSPINAL FLUID LEVEL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE;

EID: 0037348851     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.200390113     Document Type: Article

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