Identification of a fibrinolytic enzyme in Schistosoma mansoni eggs and modulated blood fibrinogen metabolism in S. mansoni-infected mice

Parasitology

Volumn 126, Issue 3, 2003, Pages 231-234

  Doenhoff, M J ^a   Stanley, R G ^a   Pryce, D ^a   Curtis, R C H ^b   Parry, H ^c   Griffiths, K ^c   Jackson, C L ^d  

^a BANGOR UNIVERSITY   (United Kingdom)

^b ROTHAMSTED RESEARCH   (United Kingdom)

^c YSBYTY GWYNEDD   (United Kingdom)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Eggs; Fibrinogen; Fibrinolysis; Schistosoma mansoni; Serine protease

Indexed keywords

ANTIBODY; ANTISERUM; FIBRINOGEN; PLASMIN; SERINE PROTEINASE INHIBITOR;

ANIMAL MODEL; ARTICLE; BLOOD; CONTROLLED STUDY; FIBRINOGEN METABOLISM; FIBRINOLYSIS; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; ZYMOGRAPHY;

ANIMALS; FIBRINOGEN; FIBRINOLYSIS; MICE; OVUM; RODENT DISEASES; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI;

ANIMALIA; SCHISTOSOMA; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; TREMATODA;

EID: 0037348090     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0031182002002809     Document Type: Article

References (15)

1. EL-BASSIOUNI, N. E., EL-BASSIOUNI, A. E., EL KHAYAT, H. R., AKL, M. M. & OMRON, S. A. (1996). Hyperfibrinolysis in hepatosplenic schistosomiasis. Journal of Clinical Pathology 49, 990-993.
2. BINI, A. & KUDRYK, B. J. (1995). Fibrinogen in human atherosclerosis. Annals of the New York Academy of Sciences 748, 461-473.
3. CURTIS, R. H. C. (1991). Characterization of some S. mansoni hydrolases and other surface antigens. Ph.D. thesis, University of London.
4. DE GAETANO, G. & CERLETTI, C. (2002). Platelet adhesion and aggregation and fibrin formation in flowing blood: a historical contribution by Giulio Bizzozero. Platelets 13, 85-89.
5. DOENHOFF, M. J., PEARSON, S., DUNNE, D. W., BICKLE, Q., BARN, J. & HASSOUNAH, O. (1981). Immunological control of hepatotoxicity and parasite egg excretion in Schistosoma mansoni infections - stage specificity of the reactivity of immune serum in T-cell deprived mice. Transactions of the Royal Society of Tropical Medicine and Hygiene 75, 41-53.
6. DOENHOFF, M. J., STANLEY, R. G., GRIFFITHS, K. & JACKSON, C. L. (2002). An anti-atherogenic effect of Schistosoma mansoni infections in mice associated with a parasite-induced lowering of blood total cholesterol. Parasitology 125, 415-421.
7. KOOPMAN, J., MAAS, A., REZAEE, F., HAVEKES, L., VERHEIJEN, J., GIJBELS, M. & HAVERKATE, F. (1997). Fibrinogen and atherosclerosis: A study in transgenic mice. Fibrinolysis and Proteolysis 11 (Suppl.) S19-S21.
8. LOCKWOOD, B. C., NORTH, M.J., SCOTT, K. I., BREMNER, A. F. & COOMBS, G. H. (1987). The use of a highly sensitive electrophoretic method to compare the proteinases of trichomonads. Molecular and Biochemical Parasitology 24, 89-95.
9. LAEMMLI, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, London 227, 680-685.
10. LEVENSON, J., GIRAL, P., MEGNIEN, J. L., GARIEPY, J. L., PLAINFOSSE, M. C. & SIMON, A. (1997). Fibrinogen and its relations to subclinical extracoronary and coronary atherosclerosis in hypercholesterolaemic men. Arteriosclerosis, Thrombosis and Vascular Biology 17, 45-50.
11. NGAIZA, J. R. & DOENHOFF, M. J. (1990). Blood platelets and schistosome egg excretion. Proceedings of the Society for Experimental Biology and Medicine 193, 73-79.
12. SMITHERS, S. R. & TERRY, R. J. (1965). The infection of laboratory hosts with cercariae of Schistosoma mansoni and the recovery of adult worms. Parasitology 55, 695-700.
13. TOWBIN, H., STAEHELIN, T. & GORDON, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceedings of the National Academy of Sciences, USA 76, 4350-4354.
14. TRIBOUILLOY, C., PELTIER, M., COLAS, L., SENNI, M., GANRY, O., REY, J. L. & LESBRE, J. P. (1998). Fibrinogen is an independent marker for thoracic aortic atherosclerosis. The American Journal of Cardiology 81, 321-326.
15. XIAO, Q., DANTON, M.J.S., WITTE, D.P., KOWALA, M. D., VALENTINE, M. T. & DEGEN, J. L. (1998). Fibrinogen deficiency is compatible with the development of atherosclerosis in mice. Journal of Clinical Investigation 101, 1184-1194.