Presurgical evaluation of epilepsy by brain diffusion: MR-detected effects of flumazenil on the epileptogenic focus

Epilepsia

Volumn 44, Issue 3, 2003, Pages 399-407

  Konermann, Stefan ^a   Marks, Sonja ^a   Ludwig, Tanja ^a   Weber, Johannes ^a   De Greiff, Armin ^a   Dörfler, Arnd ^a   Leonhardt, Georg ^a   Wiedemayer, Helmut ^a   Diener, Hans Christoph ^a   Hufnagel, Andreas ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Diffusion MRI; Epilepsy focus; Epilepsy surgery; Flumazenil; Seizure

Indexed keywords

FLUMAZENIL;

ADULT; ARTICLE; BRAIN REGION; CLINICAL ARTICLE; COMPLEX PARTIAL SEIZURE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DIFFUSION WEIGHTED IMAGING; EPILEPTOGENESIS; FEMALE; HIPPOCAMPUS; HUMAN; INTRACTABLE EPILEPSY; MALE; PRIORITY JOURNAL; SIMPLE PARTIAL SEIZURE; STATISTICAL ANALYSIS; SUBICULUM; TEMPORAL LOBE EPILEPSY;

ADULT; BRAIN MAPPING; CEREBRAL CORTEX; DIFFUSION MAGNETIC RESONANCE IMAGING; EPILEPSY; EPILEPSY, TEMPORAL LOBE; FEMALE; FLUMAZENIL; FUNCTIONAL LATERALITY; HIPPOCAMPUS; HUMANS; MALE; MIDDLE AGED; PARAHIPPOCAMPAL GYRUS; PREOPERATIVE CARE; PROSPECTIVE STUDIES; TEMPORAL LOBE;

EID: 0037347181     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1528-1157.2003.25702.x     Document Type: Article

References (38)

1. Grünwald F, Menzel C, Pavics L, et al. Ictal and interictal brain SPECT imaging in epilepsy using technetium-99m-ECD. J Nuclear Med 1994;35:1896-01.
2. Hufnagel A, Poersch M, Elger CE, et al. The clinical and prognostic relevance of the postictal slow focus in the electrocorticogram. Electroencephalogr Clin Neurophysiol 1995;94:12-18.
3. Menzel C, Hufnagel A, Grünwald F, et al. The relevance of interictal rCBF brain SPECT in temporal lobe epilepsy: diagnostical value and effects of spatial resolution. Ann Nucl Med 1995;4:215-23.
4. Adam C, Adam C, Rouleau I, et al. Postictal aphasia and paresis: a clinical and intracerebral EEG study. Can J Neurol Sci 2000;1:49-54.
5. Wyler AR, Richey ET, Atkinson RA, et al. Methohexital activation of epileptogenic foci during acute electrocorticography. Epilepsia 1987;28:490-4.
6. Hufnagel A, Burr W, Elger CE, et al. Localization of the epileptic focus during methohexital-induced anesthesia. Epilepsia 1992;33:272-84.
7. Hufnagel A, Elger CE, Böker DK, et al. Activation of the epileptic focus during intracarotid amobarbital test: electrocorticographic registration via subdural electrodes. Electroencephalogr Clin Neurophysiol 1990;75:453-63.
8. Hsieh JC, Shih YS, Hwang LD, et al. Activation of epileptogenic activities by etomidate in electrocorticoencephalography (ECoG) during operation for epilepsy. Ma Zui Xue Za Zhi 1990;28:127-35.
9. Haefely W. The preclinical pharmacology of flumazenil. Eur J Anaesthesiol 1988;2:25-36.
10. Schulze-Bonhage A, Elger CE. Induction of partial epileptic seizures by flumazenil. Epilepsia 2000;411:86-92.
11. Reith W, Elger B, Forsting M, et al. Diffusion-weighted MRI and perfusion echo-planar imaging in a rat stroke model. Neuroradiology 1995;37:7-8.
12. Nakasu Y, Nakasu S, Morikawa S, et al. Diffusion-weighted MR in experimental sustained seizures elicited with kainic acid. Am J Neuroradiol 1995;16:1185-92.
13. Wang Y, Majors A, Najm I, et al. Postictal alteration of sodium content and apparent diffusion coefficient in epileptic rat brain induced by kainic acid. Epilepsia 1996;37:1000-6.
14. Wall CJ, Kendall EJ, Obenaus A. Rapid alterations in diffusion-weighted images with anatomic correlates in the rodent model of status epilepticus. Am J Neuroradiol 2000;21:1841-52.
15. Wieshmann UC, Symms MR, Shorvon SD. Diffusion changes in status epilepticus. Lancet 1997;350:493-4.
16. Lansberg MG, O'Brien MW, Norbash AM, et al. MRI abnormalities associated with partial status epilepticus. Neurology 1999;52:1021-7.
17. Diehl B, Najm I, Ruggieri P, et al. Periictal diffusion-weighted imaging in a case of lesional epilepsy. Epilepsia 1999;40:1667-71.
18. Gass A, Hirsch J, Pohlmann-Eden B. Ictal multimodal MRI in focal epilepsy. Epilepsia 1999;40:190.
19. Flacke S, Wullner U, Keller E, et al. Reversible changes in echo planar perfusion- and diffusion-weighted MRI in status epilepticus. Neuroradiology 2000;42:92-5.
20. Chu K, Kang DW, Kim JY, et al. Diffusion-weighted magnetic resonance imaging in nonconvulsive status epilepticus. Arch Neurol 2001;58:993-8.
21. Sagiuchi T, Ishii K, Asano Y, Aoki Y, et al. Transient seizure activity demonstrated by Tc-99m HMPAO SPECT and diffusion-weighted MR imaging. Ann Nucl Med 2001;15:267-70.
22. Yoo SY, Chang K-H, Song IC, et al. Apparent diffusion coefficient value of the hippocampus in patients with hippocampal sclerosis and in healthy volunteers. AJNR Am J Neuroradiol 2002;23:809-12.
23. Rugg-Gunn FJ, Eriksson SH, Symms MR, et al. Diffusion tensor imaging of cryptogenic and acquired partial epilepsies. Brain 2001;124:627-36.
24. Rugg-Gunn FJ, Eriksson SH, Symms MR, et al. Diffusion tensor imaging in refractory epilepsy. Lancet 2002;359:1748-51.
25. Hufnagel A, Elger CE, Durwen H, et al. Activation of the epileptic focus by transcranial magnetic stimulation of the human brain. Ann Neurol 1990;27:49-60.
26. Hart YM, Meinardi H, Sander JW, et al. The effect of intravenous flumazenil on interictal electroencephalographic epileptic activity: results of a placebo-controlled study. J Neurol Neurosurg Psychiatry 1991;54:305-9.
27. Savic I, Widen L, Stone-Elander S. Feasibility of reversing benzodiazepine tolerance with flumazenil. Lancet 1991;337:133-7.
28. Sharief MK, Sander JW, Shorvon SD. The effect of oral flumazenil on interictal epileptic activity: results of a double-blind, placebo-controlled study. Epilepsy Res 1993;15:53-60.
29. Wieshmann UC, Clark CA, Symms MR, et al. Water diffusion in the human hippocampus in epilepsy. Magn Reson Imaging 1999;17:29-36.
30. Hugg JW, Butterworth EJ, Kuzniecky RI. Diffusion mapping applied to mesial temporal lobe epilepsy: preliminary observations. Neurology 1999;53:173-6.
31. Righini A, Pierpaoli C, Alger JR, et al. Brain parenchyma apparent diffusion coefficient alterations associated with experimental complex partial status epilepticus. Magn Reson Imaging 1994;12:865-71.
32. Zhong J, Petroff OA, Prichard JW, et al. Changes in water diffusion and relaxation properties of rat cerebrum during status epilepticus. Magn Reson Med 1993;30:241-6.
33. Sloviter RS, Dempster DW. "Epileptic" brain damage is replicated qualitatively in the rat hippocampus by central injection of glutamate or aspartate but not by GABA or acetylcholine. Brain Res Bull 1985;15:39-60.
34. Olney JW, Fuller T, de Gubareff T. Acute dendrotoxic changes in the hippocampus of kainate treated rats. Brain Res 1979;176:91-100.
35. Wall CJ, Edward JK, Obenaus A. Rapid alterations in diffusion-weighted images with anatomic correlates in the rodent model of status epilepticus. AJNR Am J Neuroradiol 2000;21:1841-52.
36. Diehl B, Najm I, Ruggieri P, et al. Postictal diffusion-weighted imaging for the localization of focal epileptic areas in temporal lobe epilepsy. Epilepsia 2001;42:21-8.
37. Hufnagel A, Weber J, Marks S, et al. Brain diffusion following single seizures. Neuroimage.
38. Zhong J, Petroff OA, Pleban LA, et al. Reversible, reproducible reduction of brain water apparent diffusion coefficient by cortical electroshocks. Magn Reson Med 1997;37:1-6.