Expression of transforming growth factor-β isoforms and their receptors in lepromatous and tuberculoid leprosy

Scandinavian Journal of Immunology

Volumn 57, Issue 3, 2003, Pages 279-285

  Kiszewski, C A ^a   Becerril, E ^a   Baquera, J ^a   Aguilar, L D ^a   Hernandez Pando R ^a  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR IMMUNITY; CLINICAL ARTICLE; CLONAL ANERGY; CONTROLLED STUDY; EPITHELIUM CELL; FIBROBLAST; HAIR ROOT; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KERATINOCYTE; LEPROMATOUS LEPROSY; LYMPHOCYTE; MACROPHAGE; MORPHOMETRICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN ATROPHY; SWEAT GLAND; TISSUE REPAIR; TUBERCULOID LEPROSY;

BIOPSY; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LEPROSY, LEPROMATOUS; LEPROSY, TUBERCULOID; MYCOBACTERIUM LEPRAE; PROTEIN ISOFORMS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0037343533     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2003.01210.x     Document Type: Article

References (33)

1. Ridley DS, Jopling WH. Classification of leprosy according to immunity. A five-group system. Int J Lepr Other Mycobact Dis 1966;34:255-73.
2. Ridley DS. Histological classification and the immunological spectrum of leprosy. Bull World Health Organ 1974;51:451-65.
3. Rook GA, Hernández-Pando R. The pathogenesis of tuberculosis. Annu Rev Microbiol 1996;50:259-84.
4. Yamamura M, Uyemura K, Deans R et al. Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science 1991;254:277-9.
5. Nath I. Immunology of human leprosy - current status. Lepr Rev 1983;31-45 (Special Issue).
6. Sibley LD, Krahenbuhl JL. Induction of unresponsiveness to gamma interferon in macrophages infected with Mycobacterium leprae. Infect Immun 1988;56:1912-9.
7. Kingsley DM. The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 1994;8:133-46.
8. Letterio JL, Roberts AB. Regulation of the immune response by TGF-β. Annu Rev Immunol 1998;16:137-61.
9. Tada TS, Ohzeki S, Utsumi K et al. Transforming growth factor-beta-induced inhibition of T cell function. Susceptibility difference in T cells of various phenotypes and functions and its relevance to immunosuppression in the tumor-bearing state. J Immunol 1991;146:1077-82.
10. Pinson DM, LeClaire R, Lorchsbach RB, Parme MJ, Russell SW. Regulation by transforming growth factor-beta 1 of expression and function of the receptor for IFN-gamma on mouse macrophages. J Immunol 1992;149:2028-34.
11. Geiser AG, Letterio JJ, Kulkarni AB, Karlsson S, Roberts A, Sporn M. Transforming growth factor beta-1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype. Proc Natl Acad Sci USA 1993;90:9944-8.
12. Tsunawaki S, Sporn M, Ding A, Nathan C. Deactivation of macrophages by transforming growth factor-beta. Nature 1988;334:260-2.
13. Chantry D, Turner M, Abney E, Feldmann M. Modulation of cytokine production by transforming growth factor-beta. J Immunol 1989;142:4295-300.
14. Ding A, Nathan C, Graycar J, Derynck R, Stuehr DJ, Srimal S. Macrophage deactivating factor and transforming growth factors -beta 1, -beta 2 and -beta 3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-gamma. J Immunol 1990;145:940-4.
15. Maeda H, Kuwahara H, Ichimura Y, Ohtsuki M, Kurakata S, Shiraishi A. TGF-beta enhances macrophage ability to produce IL-10 in normal and tumor bearing mice. J Immunol 1995;15:4926-32.
16. Wrana JL, Attisano L, Wieser R, Ventura F, Massagué J. Mechanism of activation of the TGF-beta receptor. Nature 1994;370:341-7.
17. Massagué J. Receptors for the TGF-beta family. Cell 1992;69:1067-70.
18. López Casillas F, Wrana JL, Massagué J. Betaglycan presents ligand to the TGF-beta signaling receptor. Cell 1993;73:1435-44.
19. Hirsch CS, Yoneda T, Averill L, Ellner JJ, Toossi Z. Enhancement of intracellular growth of Mycobacterium tuberculosis in human monocytes by transforming growth factor beta-1. J Infect Dis 1994;170:1229-37.
20. Toossi Z, Young TG, Averill L, Hamilton BD, Shiratsuchi H, Ellner JJ. Induction of transforming growth factor beta by purified protein derivative of Mycobacterium tuberculosis. Infect Immun 1995; 63:224-8.
21. Marth T, Strober W, Kelsal BL. High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGFβ expression and T cell apoptosis. J Immunol 1996;157:2348-57.
22. Williams AO, Chanock S, Flanders KC. Transforming growth factor beta isoforms in tuberculoid and lepromatous leprosy: immunohistochemical studies. Cell Vision 1995;2:363.
23. Goulart IMB, Figuereido F, Coimbra T, Foss NT. Detection of transforming growth factor-beta 1 in dermal lesions of different clinical forms of leprosy. Am J Pathol 1996;148:911-7.
24. Hernández-Pando R, Bornstein QL, Aguilar LD, Orozco EH, Madrigal VK, Martinez Cordero E. Inflammatory cytokine production by immunological and foreign body multinucleated giant cells. Immunology 2000;100:352-8.
25. McCartney-Francis N, Mizel D, Wong H et al. Transforming growth factor beta induces monocyte chemotaxis and growth factor production. Proc Natl Acad Sci USA 1987;84:5788.
26. Inge TH, McCoy KE, Susskind BM, Barrett SK, Zhao G, Bear HD. Immunomodulatory effects of transforming growth factor beta on T lymphocytes. Induction of CD-8 expression in the CTLL-2 cell line and in normal thymocytes. J Immunol 1992;148:3847-56.
27. Modlin RL, Mehra V, Wong L et al. Suppressor T lymphocyte from lepromatous leprosy skin lesions. J Immunol 1986;137:2831-4.
28. Salgame P, Abrams JS, Clayberger C et al. Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science 1991;254:279-82.
29. Chen Y, Kuchoroo VK, Inobe J et al. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994;265:1237-40.
30. Fukaura H, Kent SC, Pietrusewicz MJ et al. Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta 1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients. J Clin Invest 1996;98:70-7.
31. Wahl SM. Transforming growth factor beta (TGF-beta) in inflammation: a cause and a cure. J Clin Immunol 1992;2:61-74.
32. Kim SJ, Angel P, Lafyatis R et al. Autoinduction of transforming growth factor beta is mediated by the AP-1 complex. Mol Cell Biol 1990;10:1492-7.
33. Sporn MB, Roberts AB. Transforming growth factor beta: recent progress and new challenges. J Cell Biol 1992;119:1017-21.