Tissue distribution of xylazine in a suicide by hanging

Journal of Analytical Toxicology

Volumn 27, Issue 2, 2003, Pages 110-112

  Moore, Karla A ^a   Ripple, Mary G ^a   Sakinedzad, Saffia ^a   Levine, Barry ^a   Fowler, David R ^a  

^a OFFICE OF THE CHIEF MEDICAL EXAMINER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SADAZINE; XYLAZINE;

ADULT; ARTICLE; AUTOPSY; CASE REPORT; CONTROLLED STUDY; DEPRESSION; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG URINE LEVEL; GAS CHROMATOGRAPHY; HANGING; HUMAN; HUMAN TISSUE; KIDNEY; MALE; MASS SPECTROMETRY; SUICIDE; TISSUE DISTRIBUTION;

EID: 0037336355     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/27.2.110     Document Type: Article

References (10)

1. G. Kroneberg, A. Oberdorf, F. Hoffmeister, and W. Wirth. On the pharmacology of 2-(2,6-dimethylphenylamino)-4H-5,6-dihydro- 1,3-thiazine (Bayer 1470), a substance inhibitory for adrenergic and cholinergic neurons (in German). Naunyn Schmiedebergs Arch. Exp. Pathol. Pharmakol. 256(2): 257-280 (1967).
2. A.G. Galanosa, D.A.A. Spyker, J.R. Shipe, and D.L. Morris. Human xylazine overdose: a comparative review with clonidine, phenothiazines and tricyclic antidepressants. Clin. Toxicol. 18(6): 663-678 (1981).
3. J.V. Kitzman, N.H. Booth, and R.C. Hatch. Antagonism of xylazine sedation by 4-aminopyridine and yohimbine in cattle. Am. J. Vet. Res. 43: 2165-2169 (1982).
4. U. Hoffman, C.M. Meister, K. Golle, and M. Zschiesche. Severe intoxication with the veterinary tranquilizer xylazine in humans. J. Anal. Toxicol. 25: 245-249 (2001).
5. B. Levine, A.J. Jenkins, M. Queen, R. Jufer, and J.E. Smialek. Distribution of venlafaxine in three postmortem cases. J. Anal. Toxicol. 20: 502-505 (1996).
6. D.G. Spoerke, A.H. Hall, M.J. Grimes, B.N. Honea, III, and B.H. Rumack. Human overdose with the veterinary tranquilizer xylazine. Am. J. Emerg. Med. 4(3): 222-224 (1986).
7. R. Garcia-Villar, P.L. Toutain, M. Alvinerie, and Y. Ruckebusch. The pharmacokinetics of xylazine hydrochloride: an interspecific study. J. Vet. Pharmacol. Ther. 4(2): 87-92 (1981).
8. S.G. Carruthers, M. Nelson, H.R. Wexler, and C.R. Stiller. Xylazine hydrochloride (Rompun) overdose in man. Clin. Toxicol. 15(3): 281-285 (1979).
9. A. Poklis, M.A. Mackell, and M.E.S. Case. Xylazine in human tissues and fluids in a case of fatal drug abuse. J. Anal. Toxicol. 9: 234-236 (1985).
10. R.E. Mittleman, W.L. Hearn, and G.W. Hime. Xylazine toxicity -literature review and report of two cases. J. Forensic Sci. 43(2): 400-402 (1998).