Construction of a recombinant orf virus that expresses an Echinococcus granulosus vaccine antigen from a novel genomic insertion site

Archives of Virology

Volumn 148, Issue 3, 2003, Pages 555-562

  Marsland, B J ^a   Tisdall, D J ^a   Heath, D D ^b   Mercer, Andrew A ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b AGRESEARCH   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ANTIGENS, HELMINTH; BASE SEQUENCE; CELL LINE; ECHINOCOCCOSIS; ECHINOCOCCUS; GENOME, VIRAL; HELMINTH PROTEINS; MALE; MOLECULAR SEQUENCE DATA; ORF VIRUS; RECOMBINATION, GENETIC; SHEEP; SHEEP DISEASES; TESTIS; VACCINES, SYNTHETIC; VIRAL PROTEINS;

ECHINOCOCCUS GRANULOSUS; INSERTION SEQUENCES; ORF VIRUS; OVIS ARIES; PARAPOXVIRUS; POXVIRIDAE; VACCINIA VIRUS; VECTORS;

EID: 0037336232     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-002-0948-6     Document Type: Article

References (26)

1. Balassu TC, Robinson AJ (1987) Orf virus replication in bovine testis cells: kinetics of viral DNA, polypeptides, and infectious virus production and analysis of virion polypeptides. Arch Virol 97: 267-278
2. Chakrabarti S, Brechling K, Moss B (1985) Vaccinia virus expression vector: Coexpression of β-galactosidase provides visual screening of recombinant virus plaques. Mol Cell Biol 5: 3403-3409
3. Chakrabarti S, Sisler JR, Moss B (1997) Compact, synthetic, vaccinia virus early/late promoter for protein expression. Biotechniques 23: 1094-1097
4. Davison AJ, Moss B (1989a) Structure of vaccinia virus early promoters. J Mol Biol 210: 749-769
5. Davison AJ, Moss B (1989b) Structure of vaccinia virus late promoters. J Mol Biol 210: 749-769
6. Deane D, McInnes CJ, Percival A, Wood A, Thomson J, Lear A, Gilray J, Fleming S, Mercer A, Haig D (2000) Orf virus encodes a novel secreted protein inhibitor of granulocyte-macrophage colony-stimulating factor and interleukin-2. J Virol 74: 1313-1320
7. Falkner FG, Chakrabarti S, Moss B (1987) pUVI: a new vaccinia virus insertion and expression vector. Nucleic Acids Res 15: 7192
8. Fleming SB, Fraser KM, Mercer AA, Robinson AJ (1991) Vaccinia virus-like early transcriptional control sequences flank an early gene in orf virus. Gene 97: 207-212
9. Fleming SB, Blok J, Fraser KM, Mercer AA, Robinson AJ (1993) Conservation of gene structure and arrangement between vaccinia virus and orf virus. Virology 195: 175-184
10. Fleming SB, Lyttle DJ, Sullivan JT, Mercer AA, Robinson AJ (1995) Genomic analysis of a transposition-deletion variant of orf virus reveals a 3.3 kbp region of non-essential DNA. J Gen Virol 76: 2969-2978
11. Fleming SB, McCaughan CA, Andrews AE, Nash AD, Mercer AA (1997) A homolog of interleukin-10 is encoded by the poxvirus orf virus. J Virol 71: 4857-4861
12. Hammond JM, Oke PG, Coupar BE (1997) A synthetic vaccinia virus promoter with enhanced early and late activity. J Virol Methods 66: 135-138
13. Lightowlers MW, Jensen O, Fernandez E, Iriarte JA, Woollard DJ, Gauci CG, Jenkins DJ, Heath DD (1999) Vaccination trials in Australia and Argentina confirm the effectiveness of the EG95 hydatid vaccine in sheep. Int J Parasitol 29: 531-534
14. Lyttle DJ, Fraser KM, Fleming SB, Mercer AA, Robinson AJ (1994) Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus. J Virol 68: 84-92
15. Mackett M, Smith GL, Moss B (1985) The construction and characterization of vaccinia virus recombinants expressing foreign genes. In: Glover DM (ed) DNA cloning: a practical approach. IRL Press, Oxford, pp 191-211
16. McInnes CJ, Wood AR, Nettleton PE, Gilray JA (2001) Genomic comparison of an avirulent strain of Orf virus with that of a virulent wild type isolate reveals that the Orf virus G2L gene is non-essential for replication. Virus Genes 22: 141-150
17. Mercer AA, Fraser KF, Barns G, Robinson AJ (1987) The structure and cloning of orf virus DNA. Virology 157: 1-12
18. Mercer AA, Lyttle DJ, Whelan EM, Fleming SB, Sullivan JT (1995) The establishment of a gene map of orf virus reveals a pattern of genomic organisation that is highly conserved among divergent poxviruses. Virology 212: 698-704
19. Mercer AA, Haig DM (1999) Parapoxviruses. In: Granoff A, Webster RG (eds) Encyclopedia of virology. Academic Press, New York, pp 1140-1146
20. Moss B (1994) Vaccinia virus transcription. In: Conway RC, Conway JW (eds) Transcription: mechanisms and regulation. Raven Press, New York, pp 185-205
21. Moss B (1996) Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety. Proc Natl Acad Sci USA 93: 11341-11348
22. Rziha HJ, Henkel M, Cottone R, Meyer M, Dehio C, Buttner M (1999) Parapoxviruses: potential alternative vectors for directing the immune response in permissive and non-permissive hosts. J Biotechnol 73: 235-242
23. Savory LJ, Stacker SA, Fleming SB, Niven BE, Mercer AA (2000) Viral vascular endothelial growth factor plays a critical role in orf virus infection. J Virol 74: 10699-10706
24. Sullivan JT, Mercer AA, Fleming SB, Robinson AJ (1994) Identification and characterization of an orf virus homologue of the vaccinia virus gene encoding the major envelope antigen p37k. Virology 202: 968-973
25. Sullivan JT, Fraser KM, Fleming SB, Robinson AJ, Mercer AA (1995) Sequence and transcriptional analysis of an orf virus gene encoding ankyrin like repeat sequences. Virus Genes 9: 277-282
26. Yuen L, Moss B (1987) Oligonucleotide sequence signaling transcriptional termination of vaccinia virus early genes. Proc Natl Acad Sci USA 84: 6417-6421