Oral treatment of organophosphate poisoning in mice

Academic Emergency Medicine

Volumn 10, Issue 3, 2003, Pages 286-288

  Bowls, Bradford J ^a   Freeman, Jack M ^a   Luna, James A ^a   Meggs, William J ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Atropine; Cholinesterase inhibitors; Mice; Organophosphate pesticides; Paraoxon; Pralidoxime

Indexed keywords

ATROPINE; ORGANOPHOSPHATE INSECTICIDE; PARAOXON; PRALIDOXIME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENVIRONMENTAL EXPOSURE; INTOXICATION; LETHALITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL; TREATMENT OUTCOME;

ANIMALS; ANTIDOTES; ATROPINE; INSECTICIDES; MALE; MICE; MICE, INBRED BALB C; MUSCARINIC ANTAGONISTS; PARAOXON; PARASYMPATHOLYTICS; PRALIDOXIME COMPOUNDS;

EID: 0037336087     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1197/aemj.10.3.286     Document Type: Article

References (5)

1. Okurmura T, Takasu N, Ishimatsu S, et al. Report on 640 victims of the Tokyo subway sarin attack. Ann Emerg Med. 1996; 28:129-35.
2. DiKart WL, Kiestra SH, Sangster B. The use of atropine and oximes in organophosphate intoxication: a modified approach. J Clin Toxicol. 1988; 26:199-208.
3. O'Shaughnessy JA, Sultatos LG. Interaction of ethanol and the organophosphorus insecticide parathion. Biochem Pharm. 1995; 50:1925-32.
4. Kondritzer AA, Zvirblis P, Goodman A, Paplanus SH. Blood levels and elimination of salts of 2-PAM in man after oral administration. J Pharm Sci. 1968; 57:1142-5.
5. Sidell FR, Groff WA, Ellin RI. Blood levels of oxime and symptoms in humans after single and multiple oral doses of 2-pyridine aldoxime methochloride. J Pharm Sci. 1969; 58:1093-8.