Early major ischemic changes on computed tomography should preclude use of tissue plasminogen activator

Stroke

Volumn 34, Issue 3, 2003, Pages 820-821

  Von Kummer, Rüdiger ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Brain ischemia; Computed tomography; Tissue plasminogen activator

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

BASAL GANGLION; BRAIN EDEMA; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PERFUSION; COMPUTER ASSISTED TOMOGRAPHY; HUMAN; MIDDLE CEREBRAL ARTERY; MORTALITY; PRIORITY JOURNAL; PROGNOSIS; RECANALIZATION; RISK FACTOR; SHORT SURVEY; STROKE;

BRAIN; BRAIN EDEMA; BRAIN ISCHEMIA; DISEASE PROGRESSION; HUMANS; PREDICTIVE VALUE OF TESTS; RECOVERY OF FUNCTION; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0037335987     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000059430.55671.56     Document Type: Short Survey

References (9)

1. Heiss W, Rosner G. Functional recovery of cortical neurons as related to degree and duration of ischemia. Ann Neurol. 1983;14:294-301.
2. Ito U, Ohno K, Nakamura R, Suganuma F, Inaba Y. Brain edema during ischemia and after restoration of blood flow: measurement of water, sodium, potassium content and plasma protein permeability. Stroke. 1979;10:542-547.
3. von Kummer R, Bourquain H, Bastianello S, Bozzao L, Manelfe C, Meier D. Hacke W. Early prediction of irreversible brain damage after ischemic stroke by computed tomography. Radiology. 2001;219:95-100.
4. Patel S, Levine S, Tilley B, Grotta J, Lu M, Frankel M, Haley E, Brott T, Broderick J, Horowitz S, et al. Lack of clinical significance of early ischemic changes on computed tomography in acute stroke. JAMA. 2001;286:2830-2838.
5. von Kummer R, Meyding-Lamadé U, Forsting M, Rosin L, Rieke K, Hacke W, Sartor K. Sensitivity and prognostic value of early computed tomography in middle cerebral artery trunk occlusion. AJNR Am J Neuroradiol. 1994;15:9-15.
6. von Kummer R, Allen K, Holle R, Bozzao L, Bastianello S, Manelfe C, Bluhmki E, Ringleb P, Meier D, Hacke W. Acute stroke: usefulness of early CT findings before thrombolytic therapy. Radiology. 1997;205:327-333.
7. Larrue V, von Kummer R, Müller A, Bluhmki E. Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II). Stroke. 2001;32:438-441.
8. Barber P, Demchuk A, Zhang J, Buchan A. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. Lancet. 2000;355:1670-1674.
9. Tanne D, Kasner S, Demchuk A, Koren-Morag N, Hanson S, Grond M, Levine S. Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice. Circulation. 2002;105:1679-1685.