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1
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0036796231
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Pharmacogenomics in schizophrenia: The quest for individualized therapy
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Basile VS, Masellis M, Potkin SG, Kennedy JL. Pharmacogenomics in schizophrenia: the quest for individualized therapy. Hum Mol Genet 2002; 11:2517-2530.
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(2002)
Hum Mol Genet
, vol.11
, pp. 2517-2530
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Basile, V.S.1
Masellis, M.2
Potkin, S.G.3
Kennedy, J.L.4
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2
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0023812652
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Clozapine for the treatment-resistant schizophrenic. A double blind comparison with chlorpromazine
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Kane J, Honigferd G, Singer J, Meltzer H. Clozapine for the treatment-resistant schizophrenic. A double blind comparison with chlorpromazine. Arch Gen Psychiatry 1988; 45:789-796.
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(1988)
Arch Gen Psychiatry
, vol.45
, pp. 789-796
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Kane, J.1
Honigferd, G.2
Singer, J.3
Meltzer, H.4
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3
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0033106068
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Benefits and pitfalls encountered in psychiatric genetic association studies
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Malhotra AK, Goldman D. Benefits and pitfalls encountered in psychiatric genetic association studies. Biol Psychiatry 1999; 45:544-550.
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(1999)
Biol Psychiatry
, vol.45
, pp. 544-550
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Malhotra, A.K.1
Goldman, D.2
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6
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0032572611
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Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response
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Arranz MJ, Munro J, Sham P, et al. Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response. Schizophr Res 1998; 32:93-99.
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(1998)
Schizophr Res
, vol.32
, pp. 93-99
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Arranz, M.J.1
Munro, J.2
Sham, P.3
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7
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0036713871
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2A receptor gene
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2A receptor gene. Am J Psychiatry 2002; 159:1593-1595. This is the first published study to examine the relationship between risperidone and serotonin receptor genetic variation.
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(2002)
Am J Psychiatry
, vol.159
, pp. 1593-1595
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Lane, H.Y.1
Chang, Y.C.2
Chiu, C.C.3
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8
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0035118875
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Serotonin transporter polymorphisms: No association with response to antipsychotic treatment, but associations with the schizoparanoid and residual subtypes of schizophrenia
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Kaiser R, Tremblay PB, Schmider J, et al. Serotonin transporter polymorphisms: no association with response to antipsychotic treatment, but associations with the schizoparanoid and residual subtypes of schizophrenia. Mol Psychiatry 2001; 6:179-185.
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(2001)
Mol Psychiatry
, vol.6
, pp. 179-185
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Kaiser, R.1
Tremblay, P.B.2
Schmider, J.3
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9
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0035863032
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6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia
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6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia. Schizophr Res 2001; 47:49-58.
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(2001)
Schizophr Res
, vol.47
, pp. 49-58
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Masellis, M.1
Basile, V.S.2
Meltzer, H.Y.3
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11
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0033623809
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The relationship between dopamine D2 receptor polymorphism at the Taq1 A locus and therapeutic response to nemonapride, a selective dopamine antagonist, in schizophrenic patients
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Suzuki A, Mihara K, Kondo T, et al. The relationship between dopamine D2 receptor polymorphism at the Taq1 A locus and therapeutic response to nemonapride, a selective dopamine antagonist, in schizophrenic patients. Pharmacogenetics 2000; 10:335-341.
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(2000)
Pharmacogenetics
, vol.10
, pp. 335-341
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Suzuki, A.1
Mihara, K.2
Kondo, T.3
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12
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0032217288
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Lack of association between a polymorphism in the promoter region of the dopamine-2 receptor gene and clozapine response
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Arranz MJ, Li T, Munro J, et al. Lack of association between a polymorphism in the promoter region of the dopamine-2 receptor gene and clozapine response. Pharmacogenetics 1998; 8:481-484.
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(1998)
Pharmacogenetics
, vol.8
, pp. 481-484
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Arranz, M.J.1
Li, T.2
Munro, J.3
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13
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0343807441
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Association of short-term response to haloperidol treatment with a polymorphism in the dopamine D2 receptor gene
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Shafer M, Rujescu D, Giegling I, et al. Association of short-term response to haloperidol treatment with a polymorphism in the dopamine D2 receptor gene. Am J Psychiatry 2001; 158:802-804. This is a well-designed study that finds a relatively strong relationship between dopamine D2 receptor genotype and response to haloperidol.
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(2001)
Am J Psychiatry
, vol.158
, pp. 802-804
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Shafer, M.1
Rujescu, D.2
Giegling, I.3
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14
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0345294193
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The serotonergic system influences individual's response to risperidone
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Mata I, Arranz MJ, Lai T, et al. The serotonergic system influences individual's response to risperidone [abstract]. Am J Med Genetics 2002; 114:728.
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(2002)
Am J Med Genetics
, vol.114
, pp. 728
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Mata, I.1
Arranz, M.J.2
Lai, T.3
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15
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0034889660
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The -141C Ins/Del polymorphism in the dopamine D2 receptor gene promoter region is associated with anxiolytic and antidepressive effects during treatment with dopamine antagonists in schizophrenic patients
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Suzuki A, Kondo T, Mihara K, et al. The -141C Ins/Del polymorphism in the dopamine D2 receptor gene promoter region is associated with anxiolytic and antidepressive effects during treatment with dopamine antagonists in schizophrenic patients. Pharmacogenetics 2001; 11:545-550.
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(2001)
Pharmacogenetics
, vol.11
, pp. 545-550
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Suzuki, A.1
Kondo, T.2
Mihara, K.3
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16
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0035986208
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Discovery and utilization of haplotypes for pharmacogenetic studies of psychotropic drug response
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Athanasiou MC, Malhotra AK, Xu C, Stephens JC. Discovery and utilization of haplotypes for pharmacogenetic studies of psychotropic drug response. Psychiatr Genet 2002; 12:89-96. This paper reviews the use of haplotypes in psychiatric pharmacogenetic studies and the potential commercial applications of this strategy.
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(2002)
Psychiatr Genet
, vol.12
, pp. 89-96
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Athanasiou, M.C.1
Malhotra, A.K.2
Xu, C.3
Stephens, J.C.4
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17
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0035969937
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Pharmacogenetic assessment of antipsychotic-induced movement disorders: Contribution of the dopamine D3 receptor and cytochrome P450 1A2 genes
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Ozdemir V, Basile VS, Masellis M, Kennedy JL. Pharmacogenetic assessment of antipsychotic-induced movement disorders: contribution of the dopamine D3 receptor and cytochrome P450 1A2 genes. J Biochem Biophys Methods 2001; 47:151-157.
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(2001)
J Biochem Biophys Methods
, vol.47
, pp. 151-157
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Ozdemir, V.1
Basile, V.S.2
Masellis, M.3
Kennedy, J.L.4
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18
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0034920248
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Dopamine D3 receptor gene and tardive dyskinesia in Chinese schizophrenic patients
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Garcia-Barcelo MM, Lam LCW, Ungvari GS, et al. Dopamine D3 receptor gene and tardive dyskinesia in Chinese schizophrenic patients. J Neural Transm 2001; 108:671-677.
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(2001)
J Neural Transm
, vol.108
, pp. 671-677
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Garcia-Barcelo, M.M.1
Lam, L.C.W.2
Ungvari, G.S.3
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19
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0035828077
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Lack of association between a functional polymorphism of the cytochrome P450 1A2 (CYP1A12) gene and tardive dyskinesia in schizophrenia
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Schulze TG, Schumacher J, Muller DJ, et al. Lack of association between a functional polymorphism of the cytochrome P450 1A2 (CYP1A12) gene and tardive dyskinesia in schizophrenia. Am J Med Genet 2001; 105:498-501.
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(2001)
Am J Med Genet
, vol.105
, pp. 498-501
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Schulze, T.G.1
Schumacher, J.2
Muller, D.J.3
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20
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0035829965
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Association between three functional polymorphisms of dopamine D2 receptor gene and tardive dyskinesia in schizophrenia
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Hori H, Ohmori O, Shinkai T, et al. Association between three functional polymorphisms of dopamine D2 receptor gene and tardive dyskinesia in schizophrenia. Am J Med Genet 2001; 105:774-778.
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(2001)
Am J Med Genet
, vol.105
, pp. 774-778
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Hori, H.1
Ohmori, O.2
Shinkai, T.3
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21
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0036283004
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Pharmacogenetics of tardive dyskinesia: Combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly poiymorphism
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Lerer B, Segman RH, Fangerau H, et al. Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly poiymorphism. Neuropsychopharmacology 2002; 27:105-119. This comprehensive analysis was conducted by pooling data from several centers around the world and suggests that dopamine D3 receptor genotypes play a role in susceptibility to tardive dyskinesia. These data suggest that multicenter collaborations may be critical for the detection of the genetic factors that underlie many complex pharmacogenetic traits.
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(2002)
Neuropsychopharmacology
, vol.27
, pp. 105-119
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Lerer, B.1
Segman, R.H.2
Fangerau, H.3
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22
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17744392199
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Association between the serotonin 2A receptor gene and tardive dyskinesia in chronic schizophrenia
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Segman RH, Heresco-Levy U, Finkel B, et al. Association between the serotonin 2A receptor gene and tardive dyskinesia in chronic schizophrenia. Mol Psychiatry 2001; 6:225-229.
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(2001)
Mol Psychiatry
, vol.6
, pp. 225-229
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Segman, R.H.1
Heresco-Levy, U.2
Finkel, B.3
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23
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0034741221
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2 receptor gene with predisposition to neuroleptic malignant syndrome
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2 receptor gene with predisposition to neuroleptic malignant syndrome. Am J Psychiatry 2001; 158:1714-1716.
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(2001)
Am J Psychiatry
, vol.158
, pp. 1714-1716
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Suzuki, A.1
Kondo, T.2
Otani, K.3
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24
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0032751075
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Antipsychotic-induced weight gain: A comprehensive research synthesis
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Allison DB, Mentore JL, Heo M, et al. Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry 1999; 156:1686-1696.
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(1999)
Am J Psychiatry
, vol.156
, pp. 1686-1696
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Allison, D.B.1
Mentore, J.L.2
Heo, M.3
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25
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0037097014
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Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
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Reynolds GP, Zhang ZJ, Zhang XB. Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet 2002; 359:2086-2087. This is the first study to utilize drug-naïve, first-episode schizophrenia patients, and includes potentially important data suggesting a genetic susceptibility to antipsychotic drug-induced weight gain.
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(2002)
Lancet
, vol.359
, pp. 2086-2087
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Reynolds, G.P.1
Zhang, Z.J.2
Zhang, X.B.3
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26
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0035749665
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Pharmacogenomics and schizophrenia: Clinical implications
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Malhotra AK. Pharmacogenomics and schizophrenia: clinical implications. Pharmacogenomics J 2001; 1:109-114.
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(2001)
Pharmacogenomics J
, vol.1
, pp. 109-114
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Malhotra, A.K.1
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