Heart rate variability and baroreflex sensitivity are reduced in chronically undernourished, but otherwise healthy, human subjects

Clinical Science

Volumn 104, Issue 3, 2003, Pages 295-302

  Vaz, Mario ^a   Bharathi, A V ^a   Sucharita, S ^a   Nazareth, D ^a  

^a ST JOHN'S NATIONAL ACADEMY OF HEALTH SCIENCES   (India)

Author keywords

Autonomic nervous system; Baroreflex; India; Nutritional status

Indexed keywords

ADULT; ANTHROPOMETRY; ARTICLE; AUTONOMIC NERVE; BODY MASS; CONTROLLED STUDY; HEART RATE VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; NERVE CONDUCTION; PARAMETER; PHYSICAL ACTIVITY; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; SOCIAL CLASS; SOCIOECONOMICS; SYSTOLIC BLOOD PRESSURE; UNDERWEIGHT;

ADOLESCENT; ADULT; AUTONOMIC NERVOUS SYSTEM; BAROREFLEX; BLOOD PRESSURE; BODY MASS INDEX; BODY WEIGHT; CHRONIC DISEASE; HEART RATE; HUMANS; MALE; NUTRITION DISORDERS; NUTRITIONAL STATUS; SOCIAL CLASS;

EID: 0037335084     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20020294     Document Type: Article

References (53)

1. Young, J. B. and MacDonald, I. A. (1992) Sympathoadrenal activity in obesity: heterogeneity of findings since 1980. Int. J. Obesity 16, 959-967
2. Vaz, M., Jennings, G., Turner, A., Cox, H., Lambert, G. and Esler, M. (1997) Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects. Circulation 96, 3423-3429
3. Grassi, G., Seravalle, G., Cattaneo, B. M. et al. (1995) Sympathetic activation in obese normotensive subjects. Hypertension 25, 560-563
4. Narkiewicz, K., van de Borne, P. J. H., Cooley, R. L., Dyken, M. E. and Somers, V. K. (1998) Sympathetic activity in obese subjects with and without obstructive sleep apnea. Circulation 98, 772-776
5. Rumantir, M. S., Vaz, M., Jennings, G. L. et al. (1999) Neural mechanisms in human obesity-related hypertension. J. Hypertens. 17, 1125-1133
6. Spraul, M., Ravussin, E., Fontvielle, A. M., Rising, R., Larson, D. E. and Anderson, E. A. (1993) Reduced sympathetic nervous activity: a potential mechanism predisposing to body weight gain. J Clin. Invest. 92, 1730-1735
7. Shetty, P. S. and James, W. P. T. (1994) Body Mass Index. A measure of chronic energy deficiency in adults. FAO Food and Nutrition Paper 56, FAO, Rome
8. Naidu, A. N. and Rao, N. P. (1994) Body mass index: a measure of the nutritional situation in Indian populations. Eur. J. Clin. Nutr. 48, S131-S140
9. Young, J. B. and Landsberg, L. (1977) Supression of sympathetic nervous system during fasting. Science 196, 1473-1475
10. Young, J. B. and Landsberg, L. (1979) Effect of diet and cold exposure on norepinephrine turnover in pancreas and liver. Am. J. Physiol. 236, E524-E533
11. Shetty, P. S., Jung, R. T. and James, W. P. T. (1979) Effect of catecholamine replacement with levodopa on the metabolic response to semistarvation. Lancet i, 77-79
12. Vaz, M., Kulkarni R. N., Leo, L. and Shetty, P. S. (1994) Plasma norepinephrine kinetics are unaltered in chronically undernourished adult subjects. Eur. J. Clin. Nutr. 48, 30-37
13. Vaz, M., Jayarajan, M. P., Kulkarni, R. N., Balasubramanyam, A. and Shetty, P. S. (1992) Parasympathetic tone in chronically energy deficient human subjects. Nutr. Res. 12, 613-620
14. Akselrod, S., Gordon, D., Ubel, F. A., Shannon, D. C., Barger, A. C. and Cohen, R. J. (1981) Power spectrum analysis of heart rate fluctuations: a quantitative probe of beat-to-beat cardiovascular control. Science 213, 220-222
15. Pagani, M., Lombardi, F., Guzzetti, S. et al. (1986) Power spectral analysis of heart rate and blood pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog. Circ. Res. 59, 178-193
16. Algra, A., Tijssen, J. G., Roelandt, J. R., Pool, J. and Lubsen, J. (1993) Heart rate variability from 24-hour electrocardiography and 2 year risk of sudden death. Circulation 88, 180-185
17. Huikuri, H. V., Valkama, J. O., Airaksinen, K. E. et al. (1993) Frequency domain measures of heart rate variability before onset of nonsustained and sustained ventricular tachycardia in patients with coronary artery disease. Circulation 87, 1220-1228
18. Tsuji, H., Venditti, F. J., Manders, E. S. et al. (1994) Reduced heart rate variability and mortality risk in an elderly cohort. The Framingham Heart Study. Circulation 90, 878-883
19. Tsuji, H., Larson, M. G., Venditti, F. J. et al. (1996) Impact of reduced heart rate variability on risk for cardiac events. The Framingham Heart Study. Circulation 94, 2850-2855
20. Bigger, Jr, J. T., La Rovere, M. T., Steinman, R. C. et al. (1989) Comparison of baroreflex sensitivity and heart rate variability after myocardial infarction. J. Am. Coll. Cardiol. 14, 1511-1518
21. Mahajan, B. K. and Gupta, M. C. (1991) Social Environment. In Textbook of Preventive and Social Medicine, pp. 82-86, Jaypee Bros, New Delhi
22. Ferro-Luzzi, A., Sette, S., Franklin, M. and James, W. P. T. (1992) A simplified approach of assessing adult chronic energy deficiency. Eur. J. Clin. Nutr. 46, 173-186
23. Durnin, J. V. G. A. and Womersley, J. (1974) Body fat assessed from total body density and its estimation from skinfold thicknesses: measurements on 481 men and women aged 16 to 72 years. Br. J. Nutr. 32, 77-97
24. Bharathi, A. V., Sandhya, N. and Vaz, M. (2000) The development and characteristics of a physical activity questionnaire for epidemiological studies in urban middle class Indians. Indian J. Med. Res. 111, 95-102
25. WHO (1997) Obesity: Preventing and Managing the Global Epidemic (Report of a WHO consultation on obesity), World Health Organisation, Geneva
26. Vaz, M., Turner, A., Kingwell, B. et al. (1995) Postprandial sympatho-adrenal activity: its relation to metabolic and cardiovascular events and to changes in meal frequency. Clin. Sci. 89, 349-357
27. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology (1996) Heart rate variability, standards of measurement, physiological interpretation and clinical use. Circulation 93, 1043-1065
28. Parati, G., Frattola, A., Di Rienzo, M., Castiglioni, P., Pedotti, A. and Mancia, G. (1995) Effects of aging on 24 hour dynamic baroreceptor control of heart rate in ambulant subjects. Am. J. Physiol. 268, H1606-H1612
29. Sucharita, S., Bharathi, A. V., Kurpad, A. V. and Vaz, M. (2002) A comparative study of tests of cardiac parasympathetic nervous activity in healthy human subjects. Physiol. Meas. 23, 347-354
30. Lang, T. A. and Secic, M. (1997) How to Report Statistics in Medicine. Annotated Guidelines for Authors, Editors, and Reviewers, pp. 47-50, American College of Physicians, Philadelphia
31. Eckberg, D. L. (1997) Sympathovagal balance: a critical appraisal. Circulation 96, 3224-3232
32. Malliani, A., Pagani, M., Montano, N. and Mela, G. S. (1998) Sympathovagal balance: a reappraisal. Circulation 98, 2640-2643
33. Malik, M. (1998) Sympathovagal balance: a critical appraisal. Circulation 98, 2643-2644
34. Malliani, A. (1999) The pattern of sympathovagal balance explored in the frequency domain. News Physiol. Sci. 14, 111-117
35. Hojgaard, M. V., Holstein-Rathlou, N.-H., Agner, E. and Kanters, J. K. (1998) Dynamics of spectral components of heart rate variability during changes in autonomic balance. Am. J. Physiol. 275, H213-H219
36. Esler, M., Jennings, G., Korner, P., Blombery, P., Sacharias, N. and Leonard, P. (1984) Measurement of total and organ-specific norepinephrine kinetics in humans. Am. J. Physiol. 247, E21-E28
37. Kollai, M., Jokkel, G., Bonyhay, I., Tomcsanyi, J. and Naszlady, A. (1994) Relation between baroreflex sensitivity and cardiac vagal tone in humans. Am. J. Physiol. 266, H21-H27
38. Ewing, D. J. (1988) Recent advances in the non-invasive investigation of diabetic autonomic neuropathy. In Autonomic Failure. A Textbook of Clinical Disorders of the Autonomic Nervous System, 2nd edn (Bannister, R., ed.), pp. 670-671, Oxford University Press, Oxford
39. Weston, P. J., James, M. A., Panerai, R. et al. (1996) Abnormal baroreceptor-cardiac reflex sensitivity is not detected by conventional tests of autonomic function in patients with insulin-dependent diabetes mellitus. Clin. Sci. 91, 59-64
40. Sozen, A. B., Demirel, S., Akkaya, V. et al. (1998) Autonomic dysfunction in vitamin B12 deficiency: a heart rate variability study. J. Auton. Nerv. Syst. 71, 25-27
41. Aytemir, K., Aksoyek, S., Buyukasik, Y. et al. (2000) Assessment of autonomic nervous system functions in patients with vitamin B12 deficiency by power spectral analysis of heart rate variability. Pacing Clin. Electrophysiol. 23, 975-978
42. Santer, R. M. and Conboy, V. B. (1990) Prenatal undernutrition permanently decreases enteric neuron number and sympathetic innervation of Auerbach's plexus in the rat. J. Anat. 168, 57-62
43. van der Heyden, J. T., Docter, R., van Toor, H., Wilson, J. H., Hennemann, G. and Krenning, E. P. (1986) Effects of caloric deprivation on thyroid hormone tissue update and generation of low-T3 syndrome. Am. J. Physiol. 251, E151-E156
44. Visser, T. J., Lamberts, S. W., Wilson, J. H., Docter, R. and Hennemann, G. (1978) Serum thyroid concentrations during prolonged reduction of dietary intake. Metab. Clin. Exp. 27, 405-409
45. Cacciotori, V., Gemma, M. L., Bellavere, F. et al. (2000) Power spectral analysis of heart rate in hypothyroidism. Eur. J. Endocrinol. 143, 327-333
46. Foley, C. M., McAllister, R. M. and Hasser, E. M. (2001) Thyroid status influences baroreflex function and autonomic contributions to arterial pressure and heart rate. Am. J. Physiol. Heart Circ. Physiol. 280, H2061-H2068
47. Petretta, M., Bonaduce, D., Scalfi, L. et al. (1997) Heart rate variability as a measure of autonomic nervous function in anorexia nervosa. Clin. Cardiol. 20, 219-224
48. Kreipe, R. E., Goldstein, B., DeKing, D. E., Tipton, R. and Kempski, M. H. (1994) Heart rate power spectrum analysis of autonomic dysfunction in adolescents with anorexia nervosa. Int. J. Eating Disord. 16, 159-165
49. Hirsch, J., Leibel, R. L., Mackintosh, R. and Aguirre, A. (1991) Heart rate variability as a measure of autonomic function during weight change in humans. Am. J. Physiol. 261, R1418-R1423
50. Soares, M. J. and Shetty, P. S. (1991) Basal metabolic rates and metabolic economy in chronic undernutrition. Eur. J. Clin. Nutr. 45, 363-373
51. Kurpad, A. V., Kulkarni, R. N., Sheela, M. L. and Shetty, P. S. (1989) Thermogenic responses to graded doses of noradrenaline in undernourished Indian male subjects. Br. J. Nutr. 61, 201-208
52. Kulkarni, R. N., Kurpad, A. V. and Shetty, P. S. (1988) Vascular adrenoceptor sensitivity to graded doses of norepinephrine infusions in undernourished subjects. Indian J. Med. Res. 88, 427-433
53. Jayarajan, M. P. and Shetty, P. S. (1992) Cardiovascular responses to sustained hand grip in chronically undernourished subjects. Int. J. Food Sci. Nutr. 43, 19-24