Evaluation of eutectic lidocaine/prilocaine cream (EMLA®) for steroid joint injection in children with juvenile rheumatoid arthritis: A double blind, randomized, placebo controlled trial

Journal of Rheumatology

Volumn 30, Issue 3, 2003, Pages 594-596

  Uziel, Yosef ^a,b,c   Berkovitch, Matitiahu ^a,d   Gazarian, Madlen ^a,e   Koren, Gideon ^a   Silverman, Earl D ^a   Schneider, Rayfel ^a   Laxer, Ronald M ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b MEIR MEDICAL CENTER   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

^d ASSAF HAROFEH MEDICAL CENTER   (Israel)

^e UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

EMLA ; Intraarticular steroid injections; Juvenile arthritis

Indexed keywords

EMLA; PLACEBO; POLYURETHAN; TETRACAINE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; INJECTION PAIN; INJECTION SITE; JUVENILE RHEUMATOID ARTHRITIS; MALE; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; TOPICAL TREATMENT; VISUAL ANALOG SCALE;

ADOLESCENT; ANESTHETICS, LOCAL; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, JUVENILE RHEUMATOID; CHILD; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INJECTIONS, INTRA-ARTICULAR; LIDOCAINE; MALE; PAIN; PATIENT SATISFACTION; PLACEBOS; PRILOCAINE; STEROIDS;

EID: 0037334580     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Dent PB, Walker N. Intra-articular corticosteroids in the treatment of juvenile rheumatoid arthritis. Curr Opin Rheumatol 1998;10:475-80.
2. Padeh S, Passwell JH. Intraarticular corticosteroid injection in the management of children with chronic arthritis. Arthritis Rheum 1998;41:1210-4.
3. Hallen B, Carlsson P, Uppfeldt A. Clinical study of a lignocaineprilocaine cream to relieve the pain of venepuncture. Br J Anaesthesia 1985;57:326-8.
4. Kapelushnik J, Koren G, Solh H, Greenberg M, DeVeber L. Evaluating the efficacy of EMLA in alleviating pain associated with lumbar puncture; comparison of open and double-blinded protocols in children. Pain 1990;42:31-4.
5. Himelstein BP, Cnaan A, Blackall CS, Zhao H, Cavalieri G, Cohen DE. Topical application of lidocaine-prilocaine (EMLA) cream reduces the pain of intramuscular infiltration of saline solution. J Pediatr 1996;129:718-21.
6. Taddio A, Nulman I, Goldbach M, Ipp M, Koren G. Use of lidocaine-prilocaine cream for vaccination pain in infants. J Pediatr 1994;124:643-8.
7. Gupta AK, Koren G, Shear NH. A double-blind, randomized, placebo-controlled trial of eutectic lidocaine/prilocaine cream 5% (EMLA) for analgesia prior to cryotherapy of warts in children and adults. Pediatr Dermatol 1998;15:129-33.
8. Lycka BA. EMLA. A new and effective topical anesthetic. J Dermatol Surg Oncol 1992;18:859-62.
9. Kerr KL, Jarvis JN. Comparison of the cost-effectiveness of EMLA cream vs oral midazolam for analgesia during pediatric arthrocentesis [abstract 1413]. Arthritis Rheum 1996;39 Suppl:S263.
10. Koren G. Use of the eutectic mixture of local anesthetics in young children for procedure-related pain. J Pediatr 1993;122 Suppl: S30-5.
11. Bjerring P, Arendt-Nielsen L. Depth and duration of skin analgesia to needle insertion after topical application of EMLA cream. Br J Anaesthesia 1990;64:173-7.
12. Arrowsmith J, Campbell C. A comparison of local anaesthetics for venepuncture. Arch Dis Child 2000;82:309-10.
13. Bishai R, Taddio A, Bar-Oz B, Freedman MH, Koren G. Relative efficacy of amethocaine gel and lidocaine-prilocaine cream for Port-a-Cath puncture in children [abstract e31]. Pediatrics 1999;104:554.
14. Goodenough B, Kampel L, Champion GD, et al. An investigation of the placebo effect and age-related factors in the report of needle pain from venipuncture in children. Pain 1997;72:383-91.