Permeation and concentration of compactin by a liquid membrane technique

Journal of Membrane Science

Volumn 213, Issue 1-2, 2003, Pages 209-219

  Ishizu, Hiroshi ^a,b   Habaki, Hiroaki ^a   Kawasaki, Junjiro ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

Carrier mediated permeation; Compactin; HMG CoA reductase inhibitor; Mass transfer coefficient; Supported liquid membrane

Indexed keywords

CARRIER CONCENTRATION; DIFFUSION; DRUG PRODUCTS; MASS TRANSFER; MECHANICAL PERMEABILITY; PH EFFECTS; REACTION KINETICS; SOLUTIONS;

SUPPORTED LIQUID MEMBRANES (SLM);

LIQUID MEMBRANES;

1,3,5 TRIMETHYLBENZENE; AMINE; COMPACTIN; DIOCTYLAMINE; OIL; TOLUENE; UNCLASSIFIED DRUG;

CONCENTRATION; LIQUID MEMBRANE; MASS TRANSFER; MEMBRANE; PERMEABILITY;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL PARAMETERS; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; CONCENTRATION (PARAMETERS); DISSOCIATION CONSTANT; EXPERIMENTAL TEST; HYPERLIPIDEMIA; JOB PERFORMANCE; LIQUID MEMBRANE; MOLECULE; NONHUMAN; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

EID: 0037332572     PISSN: 03767388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-7388(02)00528-8     Document Type: Article

References (13)

1. Endo A. Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA Reductase. J. Med. Chem. 28:1985;401-405.
2. Monger D.J., Lim W.A., Kezdy F.J., Law J.H. Compactin inhibits insect HMG-CoA reductase and juvenile hormone biosynthesis. Biochem. Biophys. Res. Com. 105:1982;1374-1380.
3. Fears R. Sterol biosynthesis: effect of compactin and its derivatives. Biochem. Soc. Trans. 11:1983;642-644.
4. Reisinger H., Marr R. Comparison of the separation of lactic acid and L-leucine by liquid membranes. J. Membr. Sci. 80:1993;85-97.
5. Thien M.P., Hatton T.A. Liquid emulsion membranes and their applications in biochemical processing. Sep. Sci. Technol. 23:1988;819-853.
6. Lee K.H., Lee S.C., Lee W.K. Penicillin G extraction from model media using an emulsion liquid membrane: a theoretical model product decomposition. J. Chem. Technol. Biotechnol. 59:1994;365-370.
7. Juang R., Lee S., Shiau R. Carrier-facilitated liquid membrane extraction of penicillin G from aqueous streams. J. Membr. Sci. 146:1998;95-104.
8. Sahoo G.C., Dutta N.N., Dass N.N. Liquid membrane extraction of cephalosporin-C from fermentation broth. J. Membr. Sci. 157:1999;251-261.
9. Kawasaki J., Egashira R., Kawai T., Hara H., Boyadzhiev L. Recovery of erythromycin by a liquid membrane. J. Membr. Sci. 112:1996;209-217.
10. Habaki H., Isobe S., Egashira R., Kawasaki J. Permeation and concentration of erythromycin by supported and emulsion liquid membrane. J. Chem. Eng. Jpn. 31:1998;47-54.
11. Reschke M., Schügerl K. Reactive extraction of penicillin II: distribution coefficient and degrees of extraction. Chem. Eng. J. 28:1984;B11-B20.
12. Bora M.M., Dutta N.N., Bhattacharya K.G. Extraction of 7-aminocephalosporanic acid with secondary, tertiary, and quaternary amines. J. Chem. Eng. Data. 43:1988;318-324.
13. Wilke C.R., Chang P. Correlation of diffusion coefficients in dilute solutions. AIChE J. 1:1955;261-270.