Statins and myotoxicity [1]

Trends in Pharmacological Sciences

Volumn 24, Issue 3, 2003, Pages 113-114

  Yan, Lin ^a   Lan, Fen ^b   Wang, Zhen Gang ^c   Li, You Ping ^d  

^a SICHUAN UNIVERSITY   (China)

^b State Drug Administration   (China)

^c Professional Committee of Pharmacology on Traditional Chinese Medicine and Natural Medicine   (China)

^d SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; CERIVASTATIN; CLOPIDOGREL; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; FLUINDOSTATIN; GEMFIBROZIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; PRAVASTATIN; SIMVASTATIN; PYRIDINE DERIVATIVE;

DRUG METABOLISM; DRUG SAFETY; FOOD DRUG INTERACTION; HUMAN; INCIDENCE; KIDNEY FAILURE; LETTER; PATHOGENESIS; PRIORITY JOURNAL; RHABDOMYOLYSIS; WORLD HEALTH ORGANIZATION; AREA UNDER THE CURVE; BIOAVAILABILITY; CHEMICALLY INDUCED DISORDER;

AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; PYRIDINES; RHABDOMYOLYSIS;

EID: 0037332357     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(03)00022-1     Document Type: Letter

References (6)

1. Safety Information (2002) WHO international drug monitoring cerivastatin and gemfibrozil. WHO Drug Information 16, 8-11.
2. Evans M., Rees A. Effects of HMG-CoA reductase inhibitors on skeletal muscle - are all statins the same? Drug Safety. 25:2002;649-663.
3. Hodel C. Myopathy and rhabdomyolysis with lipid-lowering drugs. Toxicol. Lett. 128:2002;159-168.
4. Lilja J.J., et al. Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin. Clin. Pharmacol. Ther. 68:2000;384-390.
5. Kantola T., et al. Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. Clin. Pharmacol. Ther. 63:1998;397-402.
6. Lilja J.J., et al. Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin. Pharmacol. Ther. 66:1999;118-127.