Heterogeneity of presynaptic muscarinic receptors mediating inhibition of sympathetic transmitter release: A study with M 2- and M 4-receptor-deficient mice

British Journal of Pharmacology

Volumn 138, Issue 3, 2003, Pages 469-480

  Trendelenburg, Anne Ulrike ^a,c   Gomeza, Jesus ^b   Klebroff, Werner ^a   Zhou, Hongxia ^a   Wess, Jürgen ^b  

^a Inst Experimentelle/Klinische P   (Germany)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

3H noradrenaline; Heterogeneity; M 2 knockout; M 4 knockout; Mouse atria; Mouse urinary bladder; Mouse vas deferens; Muscarinic receptor subtypes; Presynaptic muscarinic receptors; Sympathetic axon terminals

Indexed keywords

ACETYLCHOLINE; CARBACHOL; IPRATROPIUM BROMIDE; METHOCTRAMINE; MUSCARINIC M2 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC RECEPTOR; NORADRENALIN; PHYSOSTIGMINE; PIRENZEPINE; RECEPTOR SUBTYPE; TRITIUM;

ACETYLCHOLINE RELEASE; ADRENERGIC SYSTEM; ANIMAL TISSUE; ARTICLE; BLADDER; CONTROLLED STUDY; DRUG ACTIVITY; ELECTROSTIMULATION; EVOKED RESPONSE; HEART ATRIUM; KNOCKOUT MOUSE; MEDIATOR; MOUSE; MOUSE STRAIN; NONHUMAN; NORADRENALIN RELEASE; POSTGANGLIONIC NERVE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN LOCALIZATION; RECEPTOR OCCUPANCY; REGULATORY MECHANISM; SYMPATHETIC NERVE; TISSUE DISTRIBUTION; VAS DEFERENS;

ACETYLCHOLINE; ANIMALS; CARBACHOL; CHOLINERGIC AGONISTS; DIAMINES; GENETIC HETEROGENEITY; HEART ATRIA; MALE; MICE; MICE, KNOCKOUT; MUSCARINIC ANTAGONISTS; NOREPINEPHRINE; PIRENZEPINE; RECEPTOR, MUSCARINIC M2; RECEPTOR, MUSCARINIC M4; RECEPTORS, MUSCARINIC; RECEPTORS, PRESYNAPTIC; URINARY BLADDER; VAS DEFERENS;

EID: 0037331584     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705053     Document Type: Article

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