Analysis of the initial burst of drug release coupled with polymer surface degradation

Pharmaceutical Research

Volumn 20, Issue 2, 2003, Pages 149-152

  Lee, Joo Woon ^a,c   Gardella Jr , Joseph A ^a   Hicks Jr , Wesley ^b   Hard, Robert ^a   Bright, Frank V ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Biodegradable polymers; Degradation kinetics; Drug delivery; Secondary ion mass spectrometry; Simultaneous surface analysis

Indexed keywords

PHENYL GROUP; POLYLACTIC ACID; TRIPHENYLAMINE; UNCLASSIFIED DRUG;

ARTICLE; DEGRADATION KINETICS; DRUG ACCUMULATION; DRUG DEGRADATION; DRUG HYDROLYSIS; DRUG RELEASE; IN VITRO STUDY; MASS SPECTROMETRY; PH; PRIORITY JOURNAL; SURFACE PROPERTY; TEMPERATURE;

PHARMACEUTICAL PREPARATIONS; POLYMERS; SURFACE PROPERTIES;

EID: 0037331304     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022202632685     Document Type: Article

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