Delivery of a growth factor fusion protein having collagen-binding activity to wound tissues

Artificial Organs

Volumn 27, Issue 2, 2003, Pages 147-154

  Ishikawa, Tetsuya ^a   Terai, Hiroshi ^a   Yamamoto, Takashi ^a   Harada, Kazumichi ^a   Kitajima, Takashi ^a  

^a TERUMO CORPORATION   (Japan)

Author keywords

Collagen binding; Delivery system; Fusion protein; Growth factor; Tissue regeneration

Indexed keywords

CARDIOVASCULAR SYSTEM; COLLAGEN; HISTOLOGY; TISSUE;

ACTIVE FUSION; BINDING ACTIVITIES; COLLAGEN BINDING; COLLAGEN BINDING DOMAIN; DELIVERY SYSTEMS; EPIDERMAL GROWTH FACTORS; FUSION PROTEINS; GROWTH FACTOR; HIND LIMBS; WOUND TISSUE;

TISSUE REGENERATION;

COLLAGEN TYPE 1; EPIDERMAL GROWTH FACTOR; FIBRONECTIN; HYBRID PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INJURY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FOGARTY CATHETER; GRANULATION TISSUE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RABBIT; RAT; REVASCULARIZATION; SKIN INJURY; TIBIALIS ANTERIOR MUSCLE; TISSUE REGENERATION; WOUND; WOUND HEALING; WOUND HEALING IMPAIRMENT;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0037331130     PISSN: 0160564X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1594.2003.07009.x     Document Type: Conference Paper

References (18)

1. Langer R, Moses M. Biocompatible controlled release polymers for delivery of polypeptides and growth factors. J Cell Biochem 1991;45:340-5.
2. Nimni ME. Review. Polypeptide growth factors: targeted delivery systems. Biomaterials 1997;18:1201-25.
3. Tabata Y, Ikada Y. Protein release from gelatin matrices. Adv Drug Deliv Rev 1998;31:287-1.
4. Ishikawa T, Terai H, Kitajima T. Production of a biologically active epidermal growth factor fusion protein with high collagen affinity. J Biochem (Tokyo) 2001;129:627-33.
5. Reidy MA, Clowes AW, Schwartz SM. Endothelial regeneration, V. Inhibition of endothelial regrowth in arteries of rat and rabbit. Lab Invest 1983;49:569-75.
6. Skorstengaard K, Thogersen HC, Petersen TE. Complete primary structure of the collagen-binding domain of bovine fibronectin. Eur J Biochem 1984;140:235-43.
7. Kornblihtt AR, Umezawa K, Vibe-Pedersen K, Baralle FE. Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene. EMBO J 1985;4:1755-59.
8. Tsuboi R, Rifkin DB. Recombinant basic fibroblast growth factor stimulates wound healing in healing-impaired db/db mice. J Exp Med 1990:245-51.
9. Greenhalgh DG, Sprugel KH, Murray MJ, Ross R. PDGF and FGF stimulate wound healing in the genetically diabetic mouse. Am J Pathol 1990;136:1235-46.
10. Brown RL, Breeden MP, Greenhalgh DG. PDGF and TGF-α act synergistically to improve wound healing in the genetically diabetic mouse. J Surg Res 1994;56:562-70.
11. Asahara T, Bauters C, Pastore C, Kearney M, Rossow S, Bunting S, Ferrara N, Symes JF, Isner JM. Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery. Circulation 1995;91:2793-801.
12. Yasuda S, Noguchi T, Gohda M, Arai T, Tsutsui N, Matsuda T, Nonogi H. Single low-dose administration of human recombinant hepatocyte growth factor attenuates intimal hyperplasia in a balloon-injured rabbit iliac artery model. Circulation 2000;101:2546-49.
13. Takeshita S, Pu LQ, Stein LA, Sniderman AD, Bunting S, Ferrara N, Isner JM, Symes JF. Intramuscular administration of vascular endothelial growth factor induces dose-dependent collateral artery augmentation in a rabbit model of chronic limb ischemia. Circulation 1994;90:II228-34.
14. Morishita R, Nakamura S, Hayashi S, Taniyama Y, Moriguchi A, Nagano T, Taiji M, Noguchi H, Takeshita S, Matsumoto K, Nakamura T, Higaki J, Ogihara T. Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as "cytokine supplement therapy." Hypertension 1999;33:1379-84.
15. Asahara T, Chen D, Tsurumi Y, Kearney M, Rossow S, Passeri J, Symes JF, Isner JM. Accelerated restitution of endothelial integrity and endothelium-dependent function after phVEGF165 gene transfer. Circulation 1996;94:3291-302.
16. Hayashi K, Nakamura S, Morishita R, Moriguchi A, Aoki M, Matsumoto K, Nakamura T, Kaneda Y, Sakai N, Ogihara T. In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model. Gene Ther 2000;7:1664-71.
17. Tsurumi Y, Kearney M, Chen D, Silverb M, Takeshita S, Yang J, Symes JF, Isner JM. Treatment of acute limb ischemia by intramuscular injection of vascular endothelial growth factor gene. Circulation 1997;96:II382-8.
18. Taniyama Y, Morishita R, Aoki M, Nakagami H, Yamamoto K, Yamazaki K, Matsumoto K, Nakamura T, Kaneda Y, Ogihara T. Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease. Gene Ther 2001;8:181-89.