Effects of various adjuvants and a viral infection on the antibody specificity toward native or cryptic epitopes of a protein antigen

Scandinavian Journal of Immunology

Volumn 57, Issue 2, 2003, Pages 144-150

  Gomez K A ^a   Longhi, S A ^a   Marino, V J ^a   Mathieu, P A ^a   Loureiro, M E ^a   Coutelier, J P ^b   Roguin, L P ^a   Retegui, L A ^a,c  

^a Programa de Radicales Libres em Biologia   (Argentina)

^b DE DUVE INSTITUTE   (Belgium)

^c Instituto de Quimica y Fisicoquimica Biologicas Buenos Aires   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT; ANTIGEN; EPITOPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ANTIBODY TITER; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOMODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS INFECTION;

ADJUVANTS, IMMUNOLOGIC; ALUM COMPOUNDS; ANIMALS; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; ARTERIVIRUS INFECTIONS; AUTOANTIBODIES; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FEMALE; FREUND'S ADJUVANT; HUMAN GROWTH HORMONE; KIDNEY; LACTATE DEHYDROGENASE-ELEVATING VIRUS; LIPID A; LIVER; MICE; MICE, INBRED BALB C; MICE, INBRED CBA; MUSCLES; MYOCARDIUM;

EID: 0037329458     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2003.01208.x     Document Type: Article

References (23)

1. Schijns VEJC. Immunological concepts of vaccine adjuvant activity. Curr Opin Immunol 2000;12:456-63.
2. Gupta RK, Siber GR. Adjuvants for human vaccines-current status, problems and future prospects. Vaccine 1995;13:1263-76.
3. Cohen AD, Shoenfeld Y. Vaccine-induced autoimmunity. J Autoimmun 1996;9:699-703.
4. Shoenfeld Y, Aron-Maor A. Vaccination and autoimmunity-"vaccinosis": a dangerous liaison? J Autoimmun 2000;14:1-10.
5. Chen RT, Pless R, DeStefano F. Epidemiology of autoimmune reactions induced by vaccination. J Autoimmun 2001;16:309-18.
6. Cohen AD, Shoenfeld Y. The viral-autoimmunity relationship. Viral Immunol 1995;8:1-9.
7. Gómez KA, Coutelier J-P, Mathieu PA, Lustig L, Retegui LA. Autoantibodies to cryptic epitopes elicited by infection with lactate dehydrogenase-elevating virus. Scand J Immunol 2000;51:447-53.
8. Coutelier J-P, van der Logt JTM, Heessen FWA, Warnier G, Van Snick J. Rheumatoid factor production in 129/Sv mice: involvement of an intestinal infectious agent. J Immunol 1986;137:337-40.
9. Stieneker F, Kersten G, van Bloois L et al. Comparison of 24 different adjuvants for inactivated HIV-2 split whole virus as antigen in mice. Induction of titres of binding antibodies and toxicity of the formulations. Vaccine 1995;13:45-53.
10. Schneerson R, Fattom A, Szu SC et al. Evaluation of monophosphoryl lipid A (MPL) as an adjuvant. Enhancement of the serum antibody response in mice to polysaccharide-protein conjugates by concurrent injection with MPL. J Immunol 1991;147:2136-40.
11. Coutelier J-P, Coulie PG, Wauters P, Heremans H, van der Logt JTM. In vivo polyclonal B-lymphocyte activation elicited by murine viruses. J Virol 1990;64:5383-8.
12. Coutelier J-P, van der Logt JTM, Heessen FWA, Warnier G, Van Snick J. IgG2a restriction of murine antibodies elicited by viral infections. J Exp Med 1987;165:64-9.
13. Rowson KEK, Mahy BWJ. Lactate dehydrogenase-elevating virus. J Gen Virol 1985;66:2297-312.
14. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurements with the folin phenol reagent. J Biol Chem 1951;193:265-75.
15. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
16. Gómez KA, Coutelier J-P, Retegui LA. Changes in the specificity of antibodies in mice infected with lactate dehydrogenase-elevating virus. Scand J Immunol 1997;46:168-74.
17. McInerney TL, Brennan FR, Jones TD, Dimmock NJ. Analysis of the ability of five adjuvants to enhance immune responses to a chimeric plant virus displaying an HIV-I peptide. Vaccine 1999;17:1359-68.
18. Monteyne P, Van Broeck J, Van Snick J, Coutelier J-P. Inhibition by lactate dehydrogenase-elevating virus of "in vivo" interleukin-4 production during immunization with keyhole limpet haemocyanin. Cytokine 1993;5:394-7.
19. Coutelier J-P, Van Broeck J, Wolf S. Interleukin-12 gene expression after viral infection in the mouse. J Virol 1995;69:1955-8.
20. Markine-Goriaynoff D, Nguyen TD, Bigaignon G, Van Snick J, Coutelier J-P. Distinct requirements for IL-6 in polyclonal and specific Ig production induced microorganisms. Int Immunol 2000;13:1185-92.
21. Plagemann PGW, Rowland RRR, Even C, Faaberg KS. Lactate dehydrogenase-elevating virus: an ideal persistent virus? Springer Semin Immunopathol 1995;17:167-86.
22. van den Broek MF, Spörri R, Even C et al. Lactate dehydrogenase-elevating virus (LDV). Lifelong coexistence of virus and LDV-specific immunity. J Immunol 1997;159:1585-8.
23. Verhaddelt V, Goldman M. From autoimmune responses to autoimmune disease: what is needed? J Autoimmun 2001;16:327-30.