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Volumn 91, Issue 3, 2003, Pages 227-233

The clinical implications of the difference between castration, gonadotrophin releasing-hormone (GnRH) antagonists and agonist treatment on the morphology and expression of GnRH receptors in the rat ventral prostate

Author keywords

Agonist; Antagonist; Competitive RT PCR; GnRH receptors; Pituitary; Prostate; Rat

Indexed keywords

CETRORELIX; CYCLOPHILIN; FOLLITROPIN; FOLLITROPIN RECEPTOR; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; GONADORELIN RECEPTOR; GOSERELIN; KI 67 ANTIGEN; LUTEINIZING HORMONE; LUTEINIZING HORMONE RECEPTOR; TESTOSTERONE;

EID: 0037328865     PISSN: 14644096     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-410X.2003.03054.x     Document Type: Article
Times cited : (14)

References (35)
  • 1
    • 0028306250 scopus 로고
    • Gonadotropin-releasing hormone and its analogs
    • Conn PM, Crowley FW. Gonadotropin-releasing hormone and its analogs. Annu Rev Med 1994; 45: 391-405
    • (1994) Annu Rev Med , vol.45 , pp. 391-405
    • Conn, P.M.1    Crowley, F.W.2
  • 2
    • 0019445592 scopus 로고
    • Regulation of the rat pituitary gonadotropin-releasing hormone receptor
    • Marian J, Cooper RL, Conn PM. Regulation of the rat pituitary gonadotropin-releasing hormone receptor. Mol Pharmocol 1981; 19: 399-405
    • (1981) Mol Pharmocol , vol.19 , pp. 399-405
    • Marian, J.1    Cooper, R.L.2    Conn, P.M.3
  • 3
    • 0019540090 scopus 로고
    • Gonadotropin-releasing hormone receptors. Characterisation, physiological regulation, and relationship to reproductive function
    • Clayton NR, Catt JK. Gonadotropin-releasing hormone receptors. Characterisation, physiological regulation, and relationship to reproductive function. Endocr Rev 1981; 2: 186-209
    • (1981) Endocr Rev , vol.2 , pp. 186-209
    • Clayton, N.R.1    Catt, J.K.2
  • 4
    • 0021018238 scopus 로고
    • Gonadotrophin regulation and clinical applications of GnRH
    • Belchetz EP. Gonadotrophin regulation and clinical applications of GnRH. Clin Endocrinol Metab 1983; 12: 619-40
    • (1983) Clin Endocrinol Metab , vol.12 , pp. 619-640
    • Belchetz, E.P.1
  • 5
    • 0031639229 scopus 로고    scopus 로고
    • Endocrine therapy of prostate cancer
    • Bare RL, Torti FM. Endocrine therapy of prostate cancer. Cancer Treat Res 1998; 94: 69-87
    • (1998) Cancer Treat Res , vol.94 , pp. 69-87
    • Bare, R.L.1    Torti, F.M.2
  • 6
    • 0035046991 scopus 로고    scopus 로고
    • The gonadotropin-releasing hormone antagonist abarelix depot versus luteinizing hormone releasing hormone agonists leuprolide or goserelin, initial results of endocrinological and biochemical efficacies in patients with prostate cancer
    • Tomera K, Gleason D, Gittelman M et al. The gonadotropin-releasing hormone antagonist abarelix depot versus luteinizing hormone releasing hormone agonists leuprolide or goserelin, initial results of endocrinological and biochemical efficacies in patients with prostate cancer. J Urol 2001; 165: 1585-9
    • (2001) J Urol , vol.165 , pp. 1585-1589
    • Tomera, K.1    Gleason, D.2    Gittelman, M.3
  • 7
    • 0034810482 scopus 로고    scopus 로고
    • A Gonadotropin-releasing Hormone (GnRH) receptor specific for GnRH II in primates
    • Neill JD, Duck WL, Sellers JC, Musgrove LC. A Gonadotropin-releasing Hormone (GnRH) receptor specific for GnRH II in primates. Biochem Biophys Res Commun 2001; 282: 1012-8
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 1012-1018
    • Neill, J.D.1    Duck, W.L.2    Sellers, J.C.3    Musgrove, L.C.4
  • 8
    • 0035859957 scopus 로고    scopus 로고
    • A novel mammalian receptor for the evolutionary conserved type II GnRH
    • Millar R, Lowe S, Conklin D et al. A novel mammalian receptor for the evolutionary conserved type II GnRH. Proc Natl Acad Sci USA 2001; 98: 9636-41
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9636-9641
    • Millar, R.1    Lowe, S.2    Conklin, D.3
  • 9
    • 0027941068 scopus 로고
    • Antiproliferative effects of luteinizing hormone-releasing hormone (LHRH) agonists on human androgen-independent prostate cancer cell line DU 148: Evidence for an autocrine-inhibitory LHRH loop
    • Dondi D, Limonta P, Moretti MR, Marelli MM, Garattini E, Motta M. Antiproliferative effects of luteinizing hormone-releasing hormone (LHRH) agonists on human androgen-independent prostate cancer cell line DU 148: Evidence for an autocrine-inhibitory LHRH loop. Cancer Res 1994; 54: 4091-5
    • (1994) Cancer Res , vol.54 , pp. 4091-4095
    • Dondi, D.1    Limonta, P.2    Moretti, M.R.3    Marelli, M.M.4    Garattini, E.5    Motta, M.6
  • 10
    • 0026716297 scopus 로고
    • Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP
    • Limonta P, Dondi D, Moretti MR, Maggi R, Motta M. Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP. J Clin Endocrinol Metab 1992; 75: 207-12
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 207-212
    • Limonta, P.1    Dondi, D.2    Moretti, M.R.3    Maggi, R.4    Motta, M.5
  • 11
    • 0028203309 scopus 로고
    • Inhibition of human epithelial ovarian cancer cell growth in vitro by agonistic and antagonistic analogues of luteinizing hormone-releasing hormone
    • Yano T, Pinski J, Radulovic S, Schally AV. Inhibition of human epithelial ovarian cancer cell growth in vitro by agonistic and antagonistic analogues of luteinizing hormone-releasing hormone. Proc Natl Acad Sci USA 1994; 91: 1701-5
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1701-1705
    • Yano, T.1    Pinski, J.2    Radulovic, S.3    Schally, A.V.4
  • 12
    • 0025312993 scopus 로고
    • The effects of gonadotrophin releasing hormone analogues in prostate cancer are mediated through specific tumour receptors
    • Qayum A, Gullick W, Clayton CR, Sikora K, Waxman J. The effects of gonadotrophin releasing hormone analogues in prostate cancer are mediated through specific tumour receptors. Br J Cancer 1990; 62: 96-9
    • (1990) Br J Cancer , vol.62 , pp. 96-99
    • Qayum, A.1    Gullick, W.2    Clayton, C.R.3    Sikora, K.4    Waxman, J.5
  • 13
    • 0025612673 scopus 로고
    • The partial purification and characterization of GnRH-like activity from prostatic biopsy specimens and prostatic cancer cell lines
    • Qayum A, Gullick WJ, Mellon K et al. The partial purification and characterization of GnRH-like activity from prostatic biopsy specimens and prostatic cancer cell lines. J Steroid Biochem Mol Biol 1990; 37: 899-902
    • (1990) J Steroid Biochem Mol Biol , vol.37 , pp. 899-902
    • Qayum, A.1    Gullick, W.J.2    Mellon, K.3
  • 14
    • 0026692109 scopus 로고
    • Sustained release formulations of luteinizing hormone-releasing hormone antagonist SB-75 inhibit proliferation and enhance apoptotic cell death of human prostate carcinoma (PC-82) in male nude mice
    • Redding WT, Schally VA, Radulovic S, Milovanovic S, Szepeshazi K, Isaacs TJ. Sustained release formulations of luteinizing hormone-releasing hormone antagonist SB-75 inhibit proliferation and enhance apoptotic cell death of human prostate carcinoma (PC-82) in male nude mice. Cancer Res 1992; 52: 2538-44
    • (1992) Cancer Res , vol.52 , pp. 2538-2544
    • Redding, W.T.1    Schally, V.A.2    Radulovic, S.3    Milovanovic, S.4    Szepeshazi, K.5    Isaacs, T.J.6
  • 15
    • 0033303530 scopus 로고    scopus 로고
    • The luteinizing hormone-releasing hormone receptor in human prostate cancer cells. Messenger ribonucleic acid expression, molecular size, and signal transduction pathway
    • Limonta P, Moretti RM, Marelli MM, Dondi D, Parenti M, Motta M. The luteinizing hormone-releasing hormone receptor in human prostate cancer cells. messenger ribonucleic acid expression, molecular size, and signal transduction pathway. Endocrinology 1999; 140: 5250-6
    • (1999) Endocrinology , vol.140 , pp. 5250-5256
    • Limonta, P.1    Moretti, R.M.2    Marelli, M.M.3    Dondi, D.4    Parenti, M.5    Motta, M.6
  • 16
    • 0027974335 scopus 로고
    • Binding of a radiolabeled tumor selective GnRH analog to PC-3 human prostate cancer cells and the induction of apoptosis
    • Szende B, Takács J, Mezô I, Szegedi Z, Kéri G. Binding of a radiolabeled tumor selective GnRH analog to PC-3 human prostate cancer cells and the induction of apoptosis. Endocrine 1994; 2: 645-9
    • (1994) Endocrine , vol.2 , pp. 645-649
    • Szende, B.1    Takács, J.2    Mezô, I.3    Szegedi, Z.4    Kéri, G.5
  • 17
    • 0024405857 scopus 로고
    • Receptors for luteinizing hormone-releasing hormone, somatostatin, prolactin, and epidermal growth factor in rat and human prostate cancers and in benign prostate hyperplasia
    • Fekete M, Redding TW, Comaru-Schally AM et al. Receptors for luteinizing hormone-releasing hormone, somatostatin, prolactin, and epidermal growth factor in rat and human prostate cancers and in benign prostate hyperplasia. Prostate 1989; 14: 191-208
    • (1989) Prostate , vol.14 , pp. 191-208
    • Fekete, M.1    Redding, T.W.2    Comaru-Schally, A.M.3
  • 18
    • 0033963203 scopus 로고    scopus 로고
    • High incidence of receptors for luteinizing hormone-releasing hormone (LHRH) and LHRH receptor gene expression in human prostate cancers
    • Halmos G, Arencibia JM, Schally AV, Davis R, Bostwick DG. High incidence of receptors for luteinizing hormone-releasing hormone (LHRH) and LHRH receptor gene expression in human prostate cancers. J Urol 2000; 163: 623-9
    • (2000) J Urol , vol.163 , pp. 623-629
    • Halmos, G.1    Arencibia, J.M.2    Schally, A.V.3    Davis, R.4    Bostwick, D.G.5
  • 19
    • 0035371234 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone receptor expression in the human prostate
    • Tieva A, Stattin P, Wikstrom P, Bergh A, Damber JE. Gonadotropin-releasing hormone receptor expression in the human prostate. Prostate 2001; 47: 276-84
    • (2001) Prostate , vol.47 , pp. 276-284
    • Tieva, A.1    Stattin, P.2    Wikstrom, P.3    Bergh, A.4    Damber, J.E.5
  • 20
    • 0025647639 scopus 로고
    • Receptors for luteinizing hormone-releasing hormone (LHRH) in Dunning R3327 prostate cancers and rat anterior pituitaries after treatment with a sustained delivery system of LHRH antagonist SB-75
    • Srkalovic G, Bokser L, Radulovic S, Korkut E, Schally VA. Receptors for luteinizing hormone-releasing hormone (LHRH) in Dunning R3327 prostate cancers and rat anterior pituitaries after treatment with a sustained delivery system of LHRH antagonist SB-75. Endocrinology 1990; 127: 3052-60
    • (1990) Endocrinology , vol.127 , pp. 3052-3060
    • Srkalovic, G.1    Bokser, L.2    Radulovic, S.3    Korkut, E.4    Schally, V.A.5
  • 21
    • 0033119894 scopus 로고    scopus 로고
    • Expression of gonadotropin-releasing hormone receptor mRNA in the rat ventral prostate and dunning R3327 PAP adenocarcinoma before and after castration
    • Tieva A, Wilkstrom P, Olofsson JI, Bergh A, Damber JE. Expression of gonadotropin-releasing hormone receptor mRNA in the rat ventral prostate and dunning R3327 PAP adenocarcinoma before and after castration. Prostate 1999; 39: 101-7
    • (1999) Prostate , vol.39 , pp. 101-107
    • Tieva, A.1    Wilkstrom, P.2    Olofsson, J.I.3    Bergh, A.4    Damber, J.E.5
  • 22
    • 0028071856 scopus 로고
    • Inhibitory effects of analogs of luteinizing hormone-releasing hormone on the growth of the androgen-independent Dunning R-3327-AT-1 rat prostate cancer
    • Pinski J, Reile H, Halmos G, Groot K, Schally VA. Inhibitory effects of analogs of luteinizing hormone-releasing hormone on the growth of the androgen-independent Dunning R-3327-AT-1 rat prostate cancer. Int J Cancer 1994; 59: 51-5
    • (1994) Int J Cancer , vol.59 , pp. 51-55
    • Pinski, J.1    Reile, H.2    Halmos, G.3    Groot, K.4    Schally, V.A.5
  • 23
    • 0017848696 scopus 로고
    • The effects of LH, adrenaline and noradrenaline on testicular blood flow and plasma testosterone concentrations in anaesthetized rats
    • Damber JE, Janson PO. The effects of LH, adrenaline and noradrenaline on testicular blood flow and plasma testosterone concentrations in anaesthetized rats. Acta Endocrinal (Copenh) 1978; 88: 390-6
    • (1978) Acta Endocrinal (Copenh) , vol.88 , pp. 390-396
    • Damber, J.E.1    Janson, P.O.2
  • 24
    • 0028300686 scopus 로고
    • Nucleotide sequnce analysis of mRNAs predicts that rat pituitary and gonadal gonadotropin-releasing hormone receptor proteins have identical primary structure
    • Moumni M, Kottler M-L, Counis R. Nucleotide sequnce analysis of mRNAs predicts that rat pituitary and gonadal gonadotropin-releasing hormone receptor proteins have identical primary structure. Biochem Biophys Res Commun 1994; 200: 1359-66
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 1359-1366
    • Moumni, M.1    Kottler, M.-L.2    Counis, R.3
  • 25
    • 0023942310 scopus 로고
    • p 1B15. A cDNA clone of the rat mRNA encoding cyclophilin
    • Danielson EP, Forss-Petter S, Brow AM et al. p 1B15. A eDNA clone of the rat mRNA encoding cyclophilin. DNA 1988; 7: 261-7
    • (1988) DNA , vol.7 , pp. 261-267
    • Danielson, E.P.1    Forss-Petter, S.2    Brow, A.M.3
  • 26
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984; 133: 1710-5
    • (1984) J Immunol , vol.133 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3    Wacker, H.H.4    Schwab, U.5    Stein, H.6
  • 27
    • 0027407837 scopus 로고
    • Castration rapidly results in a major reduction in epithelial cell numbers in the rat prostate, but not in the highly differentiated Dunning R3327 prostatic adenocarcinoma
    • Westin P, Bergh A, Damber JE. Castration rapidly results in a major reduction in epithelial cell numbers in the rat prostate, but not in the highly differentiated Dunning R3327 prostatic adenocarcinoma. Prostate 1993; 22: 65-74
    • (1993) Prostate , vol.22 , pp. 65-74
    • Westin, P.1    Bergh, A.2    Damber, J.E.3
  • 28
    • 0028235123 scopus 로고
    • The use of luteinizing hormone releasing hormone agonists and antagonists in gynaecological cancers
    • Emons G, Schally VA. The use of luteinizing hormone releasing hormone agonists and antagonists in gynaecological cancers. Human Reprod Update 1994; 9: 1364-79
    • (1994) Human Reprod Update , vol.9 , pp. 1364-1379
    • Emons, G.1    Schally, V.A.2
  • 29
    • 0035852749 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone (LH-RH) antagonist Cetrorelix down-regulates the mRNA expression of pituitary receptors for LH-RH by counteracting the stimulatory effect of endogenous LH-RH
    • Kovacs M, Schally AV, Csernus B, Rekasi Z. Luteinizing hormone-releasing hormone (LH-RH) antagonist Cetrorelix down-regulates the mRNA expression of pituitary receptors for LH-RH by counteracting the stimulatory effect of endogenous LH-RH. Proc Natl Acad Sci USA 2001; 98: 1829-34
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1829-1834
    • Kovacs, M.1    Schally, A.V.2    Csernus, B.3    Rekasi, Z.4
  • 30
    • 0030961688 scopus 로고    scopus 로고
    • Regression of rat Dunning R-3327-H prostate carcinoma by treatment with targeted cytotoxic analog of luteinizing hormone-releasing hormone AN-207 containing 2-pyrrolinodoxorubicin
    • Jungwirth A, Schally VA, Nagy A et al. Regression of rat Dunning R-3327-H prostate carcinoma by treatment with targeted cytotoxic analog of luteinizing hormone-releasing hormone AN-207 containing 2-pyrrolinodoxorubicin. Int J Oncol 1997; 10: 877-84
    • (1997) Int J Oncol , vol.10 , pp. 877-884
    • Jungwirth, A.1    Schally, V.A.2    Nagy, A.3
  • 31
    • 0035046991 scopus 로고    scopus 로고
    • The gonadotropin-releasing hormone antagonist abarelix depot versus luteinizing hormone releasing hormone agonists leuprolide or goserelin. Initial results of endocrinological and biochemical efficacies in patients with prostate cancer
    • Tomera K, Gleason D, Gittelman M et al. The gonadotropin-releasing hormone antagonist abarelix depot versus luteinizing hormone releasing hormone agonists leuprolide or goserelin. initial results of endocrinological and biochemical efficacies in patients with prostate cancer. J Urol 2001; 165: 1585-9
    • (2001) J Urol , vol.165 , pp. 1585-1589
    • Tomera, K.1    Gleason, D.2    Gittelman, M.3
  • 32
    • 0027197988 scopus 로고
    • Regulation of rat pituitary gonadotropin-releasing hormone receptor mRNA levels in viva and in vitro
    • Kaiser UB, Jakubowiak A, Steinberger A, Chin WW. Regulation of rat pituitary gonadotropin-releasing hormone receptor mRNA levels in viva and in vitro. Endocrinology 1993; 133: 931-4
    • (1993) Endocrinology , vol.133 , pp. 931-934
    • Kaiser, U.B.1    Jakubowiak, A.2    Steinberger, A.3    Chin, W.W.4
  • 33
    • 0027303703 scopus 로고
    • Luteinizing hormone-releasing hormone (LHRH) in rat prostate. Characterization of LHRH peptide, messenger ribonucleic acid expression, and molecular processing of LHRH in intact and castrated male rats
    • Azad N, Uddin S, Paglia LN et al. Luteinizing hormone-releasing hormone (LHRH) in rat prostate. Characterization of LHRH peptide, messenger ribonucleic acid expression, and molecular processing of LHRH in intact and castrated male rats. Endocrinology 1993; 133: 1252-7
    • (1993) Endocrinology , vol.133 , pp. 1252-1257
    • Azad, N.1    Uddin, S.2    Paglia, L.N.3
  • 34
    • 0026736096 scopus 로고
    • Effect of microcapsules of luteinizing hormone-releasing hormone antagonist SB-75 and somatostatin analog RC-160 on endocrine status and tumor growth in the Dunning R-3327H rat prostate cancer model
    • Yano T, Pinski J, Szepeshazi K, Milanovic RS, Groot K, Schally VA. Effect of microcapsules of luteinizing hormone-releasing hormone antagonist SB-75 and somatostatin analog RC-160 on endocrine status and tumor growth in the Dunning R-3327H rat prostate cancer model. Prostate 1992; 20: 297-310
    • (1992) Prostate , vol.20 , pp. 297-310
    • Yano, T.1    Pinski, J.2    Szepeshazi, K.3    Milanovic, R.S.4    Groot, K.5    Schally, V.A.6
  • 35
    • 0031876636 scopus 로고    scopus 로고
    • Decrease in the level and mRNA expression of LH-RH and EGF receptors after treatment with LH-RH antagonist cetrorelix in DU-145 prostate tumor xenografts in nude mice
    • Lamharzi N, Halmos G, Jungwirth A, Schally AV. Decrease in the level and mRNA expression of LH-RH and EGF receptors after treatment with LH-RH antagonist cetrorelix in DU-145 prostate tumor xenografts in nude mice. Int J Oncol 1998; 13: 429-35
    • (1998) Int J Oncol , vol.13 , pp. 429-435
    • Lamharzi, N.1    Halmos, G.2    Jungwirth, A.3    Schally, A.V.4


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