The aldo-keto reductase superfamily homepage

Chemico-Biological Interactions

Volumn 143-144, Issue , 2003, Pages 621-631

  Hyndman, David ^a   Bauman, David R ^b   Heredia, Vladi V ^b   Penning, Trevor M ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

AKR Web page; Aldo keto reductase superfamily; Cluster analysis; Crystal structures; NAD(P)(H) dependent oxidoreductases

Indexed keywords

ALDEHYDE REDUCTASE; AMINO ACID; HYDROXYSTEROID DEHYDROGENASE; LIGAND; OXIDOREDUCTASE; POLYMER; POTASSIUM CHANNEL; PROTEIN; STEROID 5BETA REDUCTASE;

BETA CHAIN; CHROMOSOMAL LOCALIZATION; CONFERENCE PAPER; CRYSTAL STRUCTURE; ESCHERICHIA COLI; EUKARYOTE; INFORMATION SCIENCE; NONHUMAN; OXIDATION REDUCTION REACTION; PROKARYOTE; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; STOICHIOMETRY; UNINDEXED SEQUENCE;

ALCOHOL OXIDOREDUCTASES; ANIMALS; EVOLUTION, MOLECULAR; HUMANS; TERMINOLOGY;

ESCHERICHIA COLI; EUKARYOTA; PROKARYOTA;

EID: 0037328450     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(02)00193-X     Document Type: Conference Paper

References (6)

1. Jez J.M., Bennett M.J., Schlegel B.P., Lewis M., Penning T.M. Comparative anatomy of the aldo-keto reductase superfamily. Biochem. J. 326:1997;625-636.
2. Kavanagh K.L., Klimacek M., Nidetzky B., Wilson D.K. The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis. Biochemistry. 41:2002;8785-8795.
3. Kelly V.P., Ireland L.S., Ellis E.M., Hayes J.D. Purification from rat liver of a novel constitutively expressed member of the aldo-keto reductase 7 family that is widely distributed in extrahepatic tissues. Biochem. J. 348:2000;389-400.
4. Kozma E., Brown E., Ellis E.M., Lapthorn A.J. The crystal structure of rat liver AKR7A1: a dimeric member of the aldo-keto reductase superfamily. J. Biol. Chem. 277:2002;16285-16293.
5. Jez J.M., Flynn T.G., Penning T.M. A new nomenclature for the aldo-keto reductase superfamily. Biochem. Pharmacol. 54:1997;639-647.
6. + channel β subunit. Cell. 97:1999;943-952.