Antibiotic resistance in hospitals and intensive care units: The problem and potential solutions

Seminars in Respiratory and Critical Care Medicine

Volumn 24, Issue 1, 2003, Pages 113-119

  Weinstein, Robert A ^a,b,c  

^a Jr Hospital of Cook County   (United States)

^b Cook Co Bureau of Health Services ^*  (United States)

^c RUSH MEDICAL COLLEGE   (United States)

Author keywords

Antibiotic resistance; Infection control; Intensive care unit; Nosocomial infection

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; DALFOPRISTIN PLUS QUINUPRISTIN; IMIPENEM; LINEZOLID; METICILLIN; QUINOLONE DERIVATIVE; RIFAMPICIN; VANCOMYCIN;

ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; BACTERIAL COLONIZATION; BACTERIAL INFECTION; EVOLUTION; HOSPITAL INFECTION; HUMAN; HYGIENE; INFECTION CONTROL; INTENSIVE CARE UNIT; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; PRESCRIPTION; PRIORITY JOURNAL; REVIEW;

EID: 0037328358     PISSN: 10693424     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-37922     Document Type: Review

References (32)

1. Armstrong GL, Conn LA, Pinner RW. Trends in infectious disease mortality in the United States during the 20th century. JAMA 1999;281:61-66
2. Flaherty JP, Weinstein RA. Nosocomial infection caused by antibiotic-resistant organisms in the intensive care unit. Infect Control Hosp Epidemiol 1996;17:236-248
3. Weinstein RA, Kabins SA. Strategies for prevention and control of multiple-drug-resistant nosocomial infections. Am J Med 1981;70:449-454
4. Centers for Disease Control and Prevention. Staphylococcus aureus resistant to vancomycin: United States, 2002. Morb Mortal Wkly Rep 2002;51:565-567
5. Strausbaugh LJ, Crossley KB, Nurse BA, Thrupp LD. Antimicrobial resistance in long-term-care facilities. Infect Control Hosp Epidemiol 1996;17:129-140
6. Austin DJ, Bonten MJM, Weinstein RA, Slaughter S, Anderson RM. Vancomycin-resistant enterococci in intensive-care hospital settings: transmission dynamics, persistence and the impact of infection control programs. Proc Nat Acad Sci 1999; 96:6908-6913
7. Gold HS, Moellering RC. Antimicrobial-drug resistance. N Engl J Med 1996;335:1445-1453
8. Rasmussen BA, Bradford PA, Quinn JP, Wiener J, Weinstein RA, Bush K. Genetically diverse ceftazidime-resistant isolates from a single center: biochemical and genetic characterization of TEM-10 β-lactamases encoded by different nucleotide sequences. Antimicrob Agents Chemother 1993;37:1989-1992
9. Wiener J, Quinn JP, Bradford PA, et al. Multiple antibioticresistant Klebsiella and Escherichia coli in nursing homes. JAMA 1999;281:517-523
10. Kim WJ, Weinstein RA, Hayden MK. The changing molecular epidemiology and establishment of endemicity of vancomycin resistance in enterococci at one hospital over a 6-year period. J Infect Dis 1999;179:163-171
11. Beezhold D, Slaughter S, Hayden MK, et al. Skin colonization with vancomycin-resistant enterococci among hospitalized patients with bacteremia. Clin Infect Dis 1997;24:704-706
12. Pittet D, Mourouga P, Perneger TV. Compliance with handwashing in a teaching hospital. Ann Intern Med 1999;130: 126-130
13. Pittet D, Dharan S, Touveneau S, Sauvan V, Perneger TV. Bacterial contamination of the hands of hospital staff during routine patient care. Arch Intern Med 1999;159:821-826
14. Larson E. Skin hygiene and infection prevention: more of the same or different approaches? Clin Inf Dis 1999;29:1287-1294
15. Weinstein RA. Controlling antimicrobial resistance in hospitals: the role of infection control and antibiotic use. Emerging Infect Dis 2001;7:188-192
16. Weinstein RA, Hayden M, Slaughter S. Control of vancomycin-resistant enterococcus. Ann Intern Med 1997;126: 1001
17. Tenover FC, Arbeit RD, Goering RV, et al. How to select and interpret molecular strain typing methods for epidemiological studies of bacterial infections: a review for healthcare epidemiologists. Infect Control Hosp Epidemiol 1997;18:426-439
18. Trick WE, Weinstein RA. Hand hygiene for intensive care unit personnel: rub it in. Crit Care Med 2001;29:1083-1084
19. Boyce J. Antiseptic technology: access, affordability, and acceptance. Emerging Infect Dis 2001;7:231-233
20. Johnson S, Gerding DN, Olson MN, et al. Prospective, controlled study of vinyl glove use to interrupt Clostridium difficile nosocomial transmission. Am J Med 1990;88:137-140
21. Weinstein RA, Nathan C, Gruensfelder R, Kabins SA. Endemic aminoglycoside resistance in gram-negative bacilli: epidemiology and mechanisms. J Infect Dis 1980;141:338-345
22. Bonten MJM, Hayden MK, Nathan C, et al. Epidemiology of colonisation of patients and environment with vancomycinresistant enterococci. Lancet 1996;348:1615-1619
23. John JF, Fishman NO. Programmatic role of the infectious diseases physician in controlling antimicrobial costs in the hospital. Clin Infect Dis 1997;24:471-485
24. Lawton RM, Fridkin SK, Gaynes RP, McGowan JE. Practices to improve antimicrobial use at 47 U.S. hospitals: the status of the 1991 SHEA/IDSA position paper recommendations. Infect Control Hosp Epidemiol 2000;21:256-259
25. White AC, Atmar RL, Wilson J, Cate TR, Stager CE, Greenberg SB. Effects of requiring prior authorization for selected antimicrobials: expenditures, susceptibilities, and clinical outcomes. Clin Infect Dis 1997;25:230-239
26. Evans RS, Pestotnik SL, Classen DC, et al. A computerassisted management program for antibiotics and other anti-infective agents. N Engl J Med 1998;338:232-238
27. Schiff GD, Rucker TD. Computerized prescribing: building the electronic infrastructure for better medication usage. JAMA 1998;279:1024-1029
28. John JF. Antibiotic cycling: is it ready for prime time? Infect Control Hosp Epidemiol 2000;21:9-11
29. Gerding DN. Antimicrobial cycling: lessons learned from the aminoglycoside experience. Infect Control Hosp Epidemiol 2000;21:S12-S17
30. Rahal JJ, Urban C, Horn D, et al. Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial Klebsiella. JAMA 1998;280:1233-1237
31. Kollef MH, Vlasnik J, Sharpless L, Pasque C, Murphy D, Fraser V. Scheduled change of antibiotic classes: a strategy to decrease the incidence of ventilator-associated pneumonia. Am J Respir Crit Care Med 1997;156:1040-1048
32. Quale J, Landman D, Saurina G, Atwood E, DiTore V, Patel K. Manipulation of a hospital antimicrobial formulary to control an outbreak of vancomycin-resistant enterococci. Clin Infect Dis 1996;23:1020-1025