Distribution of ehrlichiae in tissues as determined by in-situ hybridization

Journal of Comparative Pathology

Volumn 128, Issue 2-3, 2003, Pages 182-187

  Okada, H ^a   Usuda, H ^a   Tajima, T ^b,c   Kawahara, M ^d   Yoshino, T ^a   Rikihisa, Y ^c  

^a RAKUNO GAKUEN UNIVERSITY   (Japan)

^b Osaka Prefecture University   (Japan)

^c OHIO STATE UNIVERSITY   (United States)

^d Nagoya Pub Hlth Research Institute   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIGENIN; RIBOSOME RNA; RNA 16S;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL TRANSLOCATION; BACTERIUM DETECTION; BACTERIUM IDENTIFICATION; BONE MARROW; CONTROLLED STUDY; EHRLICHIA CHAFFEENSIS; EHRLICHIOSIS; ENDOTHELIUM CELL; HISTOPATHOLOGY; IN SITU HYBRIDIZATION; INTESTINE; LIVER; LUNG; LYMPH NODE; MACROPHAGE; MALE; MONOCYTE; MOUSE; NUCLEOTIDE SEQUENCE; RNA PROBE; SPLEEN;

ANAPLASMATACEAE; EHRLICHIA; EHRLICHIA CHAFFEENSIS;

EID: 0037327362     PISSN: 00219975     EISSN: None     Source Type: Journal    
DOI: 10.1053/jcpa.2002.0624     Document Type: Article

References (23)

1. Brown, C. (1998). In situ hybridization with riboprobes: An overview for veterinary pathologists. Veterinary Pathology, 35, 159-167.
2. Brown, C. C. and Skowronek, A. J. (1990). Histologic and immunochemical study of the pathogenesis of heart-water (Cowdria ruminantium infection) in goats and mice. American Journal of Veterinary Research, 51, 1476-1480.
3. Dawson, J. E., Anderson, B. E., Fishbein, D. B., Sanchez, J. L., Goldsmith, C. S., Wilson, K. H. and Duntley, C. W. (1991). Isolation and characterization of an Ehrlichia sp. from a patient diagnosed with human ehrlichiosis. Journal of Clinical Microbiology, 29, 2741-2745.
4. Dawson, J. E., Paddock, C. D., Warner, C. K., Greer, P. W., Bartlett, J. H., Ewing, S. A., Munderloh, U. G. and Zaki, S. R. (2001). Tissue diagnosis of Ehrlichia chaffeensis in patients with fatal ehrlichiosis by use of immunohistochemistry, in situ hybridization, and polymerase chain reaction. American Journal of Tropical Medicine and Hygiene, 65, 603-609.
5. Dawson, J. E., Stallknecht, D. E., Howerth, E. W., Warner, C., Biggie, K., Davidson, W. R., Lockhart, J. M., Nettles, V. F., Olson, J. G. and Childs, J. E. (1994). Susceptibility of white-tailed deer (Odocoileus virginianus) to infection with Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis. Journal of Clinical Microbiology, 32, 2725-2728.
6. Dumler, J. S., Brouqui, P., Aronson, J., Taylor, J. P. and Walker, D. H. (1991). Identification of Ehrlichia in human tissue. New England Journal of Medicine, 325, 1109-1110.
7. Dumler, J. S., Dawson, J. E. and Walker, D. H. (1993). Human ehrlichiosis: Hematopathology and immunohistologic detection of Ehrlichia chaffeensis. Human Pathology, 24, 391-396.
8. Felek, S., Unver, A., Stich, R. W. and Rikihisa, Y. (2001). Sensitive detection of Ehrlichia chaffeensis in cultured cells, blood, and ticks by RT-PCR. Journal of Clinical Microbiology, 39, 460-463.
9. Jardine, J. E., Vogel, S. W., Van Kleef, M. and Van Der Lugt, J. J. (1995). Immunohistochemical identification of Cowdria ruminantium in formalin-fixed tissue sections from mice, sheep, cattle and goats. Onderstepoort Journal of Veterinary Research, 62, 277-280.
10. Kawahara, M., Suto, C., Shibata, S., Futohashi, M. and Rikihisa, Y. (1996). Impaired antigen specific responses and enhanced polyclonal stimulation in mice infected with Ehrlichia muris. Microbiology and Immunology, 40, 575-581.
11. Little, S. E., Stallknecht, D. E., Lockhart, J. M., Dawson, J. E. and Davidson, W. R. (1998). Natural coinfection of a white-tailed deer (Odocoileus virginianus) population with three Ehrlichia spp. Journal of Parasitology, 84, 897-901.
12. Marty, A. M., Dumler, J. S., Imes, G., Brusman, H. P., Smrkovski, L. L. and Frisman, D. M. (1995). Ehrlichiosis mimicking thrombotic thrombocytopenic purpura. Case report and pathological correlation. Human Pathology, 26, 920-925.
13. Ohashi, N., Unver, A., Zhi, N. and Rikihisa, Y. (1998a). Cloning and characterization of multigenes encoding the immunodominant 3-kilodalton major outer membrane proteins of Ehrlichia canis and application of the recombinant protein for serodiagnosis. Journal of Clinical Microbiology, 36, 2671-2680.
14. Ohashi, N., Zhi, N., Zhang, Y. and Rikihisa, Y. (1998b). Immunodominant major outer membrane proteins of Ehrlichia chaffeensis are encoded by a polymorphic multigene family. Infection and Immunity, 66, 132-139.
15. Okada, H., Tajima, T., Kawahara, M. and Rikihisa, Y. (2001). Ehrlichial proliferation and acute hepatocellular necrosis in immunocompetent mice experimentally infected with the HF strain of ehrlichia, closely related to Ehrlichia chaffeensis. Journal of Comparative Pathology, 124, 165-171.
16. Paddock, C. D., Suchard, D. P., Grumbach, K. L., Hadley, W. K., Kerschmann, R. L., Abbey, N. W., Dawson, J. E., Anderson, B. E., Sims, K. G., Dumler, J. S. and Herndier, B. G. (1993). Brief report: Fatal seronegative ehrlichiosis in a patient with HIV infection. New England Journal of Medicine, 329, 1164-1167.
17. Rikihisa, Y. (1991). The tribe Ehrlichiae and ehrlichial diseases. Clinical Microbiology Reviews, 4, 286-308.
18. Rikihisa, Y. (1999). Clinical and biological aspects of infection caused by Ehrlichia chaffeensis. Microbial Infection, 1, 367-376.
19. Rikihisa, Y., Ewing, S. A. and Fox, J. C. (1994). Western immunoblot analysis of Ehrlichia chaffeensis, E. canis, or E. ewingii infection of dogs and human. Journal of Clinical Microbiology, 32, 2107-2112.
20. Shibata, S., Kawahara, M., Rikihisa, Y., Fujita, H., Watanabe, Y., Suto, C. and Ito, T. (2000). New Ehrlichia sp. closely related to E. chaffeensis isolated from Ixodes ovatus ticks in Japan. Journal of Clinical Microbiology, 38, 1331-1338.
21. Sotomayor, E. A., Popov, V. L., Feng, H. M., Walker, D. H. and Olano, J. P. (2001). Animal model of fatal human monocytotropic ehrlichiosis. American Journal of Pathology, 158, 757-769.
22. Wen, B., Rikihisa, Y., Mott, J., Fuerst, P. A., Kawahara, M. and Suto, C. (1995). Ehrlichia muris sp. nov., identified on the basis of 16S rRNA base sequences and serological, morphological, and biological characteristics. International Journal of Systematic Bacteriology, 45, 250-254.
23. Winslow, G. M., Yager, E., Shilo, K., Collins, D. N. and Chu, F. K. (1998). Infection of the laboratory mouse with the intracellular pathogen Ehrlichia chaffeensis. Infection and Immunity, 66, 3892-3899.