메뉴 건너뛰기




Volumn 17, Issue 1, 2003, Pages 43-50

Impairment of vascular and platelet levels of nitric oxide and cyclic guanosine-′,5′-monophosphate in cyclosporin A-induced hypertensive rats

Author keywords

cGMP; Cyclosporin; Hypertension; Nitric oxide; Platelets; Rat aorta

Indexed keywords

CYCLIC GMP; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; NITRITE;

EID: 0037326672     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1472-8206.2003.00116.x     Document Type: Article
Times cited : (6)

References (49)
  • 1
    • 0024976004 scopus 로고
    • Cyclosporine
    • Kahan B.D. Cyclosporine. N. Engl. J. Med. (1989) 321 1725-1738.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1725-1738
    • Kahan, B.D.1
  • 2
    • 0021881063 scopus 로고
    • Thromboembolic complications and haemostatic changes in cyclosporin-treated cadaverickidney allograft recipients
    • Vanrenterghem Y., Roels L., Lerut T. et al. Thromboembolic complications and haemostatic changes in cyclosporin-treated cadaverickidney allograft recipients. Lancet (1985) i 999-1002.
    • (1985) Lancet , vol.1 , pp. 999-1002
    • Vanrenterghem, Y.1    Roels, L.2    Lerut, T.3
  • 3
    • 0026711085 scopus 로고
    • Pathophysiology of cyclosporin anephrotoxicity: Experimental and clinical observations
    • McNally P.G., Feehally J. Pathophysiology of cyclosporin Anephrotoxicity: experimental and clinical observations. Nephrol. Dial. Transplant. (1992) 7 791-804.
    • (1992) Nephrol. Dial. Transplant. , vol.7 , pp. 791-804
    • McNally, P.G.1    Feehally, J.2
  • 4
    • 0039897482 scopus 로고
    • Cyclosporine A and hypertension
    • Schachter M. Cyclosporine A and hypertension. J. Hypertens. (1988) 6 511-516.
    • (1988) J. Hypertens. , vol.6 , pp. 511-516
    • Schachter, M.1
  • 5
    • 0026878341 scopus 로고
    • Cyclosporine and posttransplant hypertension
    • Curtis J.J. Cyclosporine and posttransplant hypertension. J. Am. Soc. Nephrol. (1992) 2(Suppl. 1) S243-S245.
    • (1992) J. Am. Soc. Nephrol. , vol.2 , pp. S243-S245
    • Curtis, J.J.1
  • 6
    • 0028033102 scopus 로고
    • Chronic exposure to cyclosporine affects endothelial and smooth muscle reactivity in the rat aorta
    • Cartier R., Dagenais F., Hollmann C., Cambron H., Buluran J. Chronic exposure to cyclosporine affects endothelial and smooth muscle reactivity in the rat aorta. Ann. Thorac. Surg. (1994) 58 789-794.
    • (1994) Ann. Thorac. Surg. , vol.58 , pp. 789-794
    • Cartier, R.1    Dagenais, F.2    Hollmann, C.3    Cambron, H.4    Buluran, J.5
  • 8
    • 0023194494 scopus 로고
    • Induction of contraction in isolated rat aorta by cyclosporine
    • Xue H., Buroski R.D., McCarron D.A., Bennett W.M. Induction of contraction in isolated rat aorta by cyclosporine. Transplantation (1987) 43 715-718.
    • (1987) Transplantation , vol.43 , pp. 715-718
    • Xue, H.1    Buroski, R.D.2    McCarron, D.A.3    Bennett, W.M.4
  • 9
    • 0023269107 scopus 로고
    • Cyclosporine augments reactivity of isolated blood vessels
    • Lamb F.S., Webb R.C. Cyclosporine augments reactivity of isolated blood vessels. Life Sci. (1987) 40 2571-2578.
    • (1987) Life Sci. , vol.40 , pp. 2571-2578
    • Lamb, F.S.1    Webb, R.C.2
  • 10
  • 11
    • 0025076612 scopus 로고
    • Mechanism of cyclosporine potentiation of vasoconstriction of the isolated rat mesenteric arterial bed: Role of extracellular calcium
    • Rego A., Vargas R., Suarez K.R., Foegh M.L., Ramwell P.W. Mechanism of cyclosporine potentiation of vasoconstriction of the isolated rat mesenteric arterial bed: role of extracellular calcium. J. Pharmacol. Exp. Ther. (1990) 254 799-808.
    • (1990) J. Pharmacol. Exp. Ther. , vol.254 , pp. 799-808
    • Rego, A.1    Vargas, R.2    Suarez, K.R.3    Foegh, M.L.4    Ramwell, P.W.5
  • 12
    • 0033937676 scopus 로고    scopus 로고
    • Platelet activation is increased in cyclosporin A-induced hypertensive rats
    • Reis F., Tavares P., Rito L.C. et al. Platelet activation is increased in cyclosporin A-induced hypertensive rats. J. Cardiovasc. Pharmacol. (2000) 36 56-64.
    • (2000) J. Cardiovasc. Pharmacol. , vol.36 , pp. 56-64
    • Reis, F.1    Tavares, P.2    Rito, L.C.3
  • 13
    • 0028789944 scopus 로고
    • Cyclosporine A stimulates endothelin release
    • Haug C., Duell T., Voisard R. et al. Cyclosporine A stimulates endothelin release. J. Cardiovasc. Pharmacol. (1995) 26 S239-S241.
    • (1995) J. Cardiovasc. Pharmacol. , vol.26 , pp. S239-S241
    • Haug, C.1    Duell, T.2    Voisard, R.3
  • 14
    • 0032762622 scopus 로고    scopus 로고
    • The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats
    • Reis F., Tavares P., Fontes-Ribeiro C.A., Ferrer-Antunes C., Teixeira F. The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats. Thromb. Res. (1999) 96 365-372.
    • (1999) Thromb. Res. , vol.96 , pp. 365-372
    • Reis, F.1    Tavares, P.2    Fontes-Ribeiro, C.A.3    Ferrer-Antunes, C.4    Teixeira, F.5
  • 15
    • 0030844808 scopus 로고    scopus 로고
    • Cyclosporine and the rennin-angiotensin axis
    • Lee D.B.N. Cyclosporine and the rennin-angiotensin axis. Kidney Int. (1997) 52 248-260.
    • (1997) Kidney Int. , vol.52 , pp. 248-260
    • Lee, D.B.N.1
  • 16
    • 0033839925 scopus 로고    scopus 로고
    • The distribution of catecholamines between plasma and platelets in cyclosporin A-induced hypertensive rats
    • Reis F., Tavares P., Teixeira F. The distribution of catecholamines between plasma and platelets in cyclosporin A-induced hypertensive rats. Pharmacol. Res. (2000) 41 129-135.
    • (2000) Pharmacol. Res. , vol.41 , pp. 129-135
    • Reis, F.1    Tavares, P.2    Teixeira, F.3
  • 17
    • 0025002980 scopus 로고
    • Cyclosporine-induced sympathetic activation and hypertension after heart transplantation
    • Scherrer U., Vissing S.F., Morgan B.J. et al. Cyclosporine-induced sympathetic activation and hypertension after heart transplantation. N. Engl. J. Med. (1990) 323 693-699.
    • (1990) N. Engl. J. Med. , vol.323 , pp. 693-699
    • Scherrer, U.1    Vissing, S.F.2    Morgan, B.J.3
  • 18
    • 0029850994 scopus 로고    scopus 로고
    • Sympathetic neural mechanisms of cyclosporine-induced hypertension
    • Sander M. Sympathetic neural mechanisms of cyclosporine-induced hypertension. Am. J. Hypertens. (1996) 9 121S-138S
    • (1996) Am. J. Hypertens. , vol.9 , pp. 121S-138S
    • Sander, M.1
  • 19
    • 0028877080 scopus 로고
    • Endothelium-dependent relaxation in the isolated rat kidney: Impairment by cyclosporine A
    • Stephan D., Billing A., Krieger J.P. et al. Endothelium-dependent relaxation in the isolated rat kidney: impairment by cyclosporine A. J. Cardiovasc. Pharmacol. (1995) 26 859-868.
    • (1995) J. Cardiovasc. Pharmacol. , vol.26 , pp. 859-868
    • Stephan, D.1    Billing, A.2    Krieger, J.P.3
  • 21
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S., Higgs A. The L-arginine-nitric oxide pathway. N. Engl. J. Med. (1993) 329 2002-2012.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 22
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada S., Palmer R.M.J., Higgs E.A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. (1991) 43 109-142.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 23
    • 0029619651 scopus 로고
    • The pathogenesis of cardiovascular disease: Role of the endothelium as a target and mediator
    • Luscher T.F., Noll G. The pathogenesis of cardiovascular disease: role of the endothelium as a target and mediator. Atherosclerosis (1995) 118(Suppl.) S81-S90.
    • (1995) Atherosclerosis , vol.118 , pp. S81-S90
    • Luscher, T.F.1    Noll, G.2
  • 24
    • 0025366847 scopus 로고
    • An L-arginine/nitricoxide pathway present in human platelets regulates aggregation
    • Radomski M.W., Palmer R.M.J., Moncada S. An L-arginine/nitricoxide pathway present in human platelets regulates aggregation. Proc. Natl. Acad. Sci. USA (1990) 87 5193-5197.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5193-5197
    • Radomski, M.W.1    Palmer, R.M.J.2    Moncada, S.3
  • 25
    • 0029257415 scopus 로고
    • Identification of constitutive and inducible forms of nitric oxide synthase in human platelets
    • Mehta J.L., Chen L.Y., Kone B.C., Mehta P., Turner P. Identification of constitutive and inducible forms of nitric oxide synthase in human platelets. J. Lab. Clin. Med. (1995) 125 370-377.
    • (1995) J. Lab. Clin. Med. , vol.125 , pp. 370-377
    • Mehta, J.L.1    Chen, L.Y.2    Kone, B.C.3    Mehta, P.4    Turner, P.5
  • 26
    • 0028287799 scopus 로고
    • Platelets and atheriosclerosis
    • White J.G. Platelets and atheriosclerosis. Eur. J. Clin. Invest. (1994) 24 25-29.
    • (1994) Eur. J. Clin. Invest. , vol.24 , pp. 25-29
    • White, J.G.1
  • 28
    • 0027174717 scopus 로고
    • Evidence for altered platelet nitric oxide synthesis in essential hypertension
    • Cadwgan T.M., Benjamin N. Evidence for altered platelet nitric oxide synthesis in essential hypertension. J. Hypertens. (1993) 11 417-420.
    • (1993) J. Hypertens. , vol.11 , pp. 417-420
    • Cadwgan, T.M.1    Benjamin, N.2
  • 29
    • 0032227296 scopus 로고    scopus 로고
    • Use of arginine analogs as inhibitors of nitric oxide synthase in rat-aortic rings
    • Titheradge M.A. (Ed.), Humana Press, Totowa, NJ
    • Russell R.J. Use of arginine analogs as inhibitors of nitric oxide synthase in rat-aortic rings, in: Titheradge M.A. (Ed.), Nitric oxide protocols. Humana Press, Totowa, NJ, 1998. pp. 243-250.
    • (1998) Nitric Oxide Protocols , pp. 243-250
    • Russell, R.J.1
  • 31
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. (1976) 72 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 32
    • 0027417136 scopus 로고
    • Endothelial and vascular smooth muscle function after chronic treatmentwith cyclosporin A
    • Auch-Schwelk W., Bossaller C., Gotze S., Thelen J., Fleck E. Endothelial and vascular smooth muscle function after chronic treatmentwith cyclosporin A. J. Cardiovasc. Pharmacol. (1993) 21 435-440.
    • (1993) J. Cardiovasc. Pharmacol. , vol.21 , pp. 435-440
    • Auch-Schwelk, W.1    Bossaller, C.2    Gotze, S.3    Thelen, J.4    Fleck, E.5
  • 33
    • 0029976920 scopus 로고    scopus 로고
    • L-Arginine restores suppressed acetylcholine-induced endothelium-dependent vascularrelaxation in cyclosporin A-treated rats
    • Kim H.S., Kim D.H., Kang S.W. et al. L-Arginine restores suppressed acetylcholine-induced endothelium-dependent vascularrelaxation in cyclosporin A-treated rats. Transplant. Proc. (1996) 28 1372-1374.
    • (1996) Transplant. Proc. , vol.28 , pp. 1372-1374
    • Kim, H.S.1    Kim, D.H.2    Kang, S.W.3
  • 35
    • 0031791945 scopus 로고    scopus 로고
    • Role of nitric oxide in cyclosporin A-induced hypertension
    • Oriji G.K., Keiser H.R. Role of nitric oxide in cyclosporin A-induced hypertension. Hypertension (1998) 32 849-855.
    • (1998) Hypertension , vol.32 , pp. 849-855
    • Oriji, G.K.1    Keiser, H.R.2
  • 36
    • 0032737119 scopus 로고    scopus 로고
    • Nitric oxide in cyclosporin A-induced hypertension: Role of protein kinase C
    • Oriji G.K., Keiser H.R. Nitric oxide in cyclosporin A-induced hypertension: role of protein kinase C. Am. J. Hypertens. (1999) 12 1091-1097.
    • (1999) Am. J. Hypertens. , vol.12 , pp. 1091-1097
    • Oriji, G.K.1    Keiser, H.R.2
  • 37
    • 0033281412 scopus 로고    scopus 로고
    • Effects of L-arginine on cyclosporin-induced alterations of vascular NO/cGMP generation
    • Lee J., Kim S.W., Kook H., Kang D.G., Kim N.H., Choi K.C. Effects of L-arginine on cyclosporin-induced alterations of vascular NO/cGMP generation. Nephrol. Dial. Transplant. (1999) 14 2634-2638.
    • (1999) Nephrol. Dial. Transplant. , vol.14 , pp. 2634-2638
    • Lee, J.1    Kim, S.W.2    Kook, H.3    Kang, D.G.4    Kim, N.H.5    Choi, K.C.6
  • 38
    • 0028235320 scopus 로고
    • Suppression of nitric oxideproduction by cyclosporin A and FK506 in rat vascular smooth muscle cells
    • Akita K., Dusting G.J., Hickey H. Suppression of nitric oxideproduction by cyclosporin A and FK506 in rat vascular smooth muscle cells. Clin. Exp. Pharmacol. (1994) 21 231-233.
    • (1994) Clin. Exp. Pharmacol. , vol.21 , pp. 231-233
    • Akita, K.1    Dusting, G.J.2    Hickey, H.3
  • 39
    • 0028910043 scopus 로고
    • Cyclosporin A inhibits nitric oxide synthase induction in vascular smooth muscle cells
    • Marumo T., Nakaki T., Hishikawa K., Suzuki H., Kato R., Saruta T. Cyclosporin A inhibits nitric oxide synthase induction in vascular smooth muscle cells. Hypertension (1995) 25(Part 2) 764-768.
    • (1995) Hypertension , vol.25 , pp. 764-768
    • Marumo, T.1    Nakaki, T.2    Hishikawa, K.3    Suzuki, H.4    Kato, R.5    Saruta, T.6
  • 40
    • 7344249590 scopus 로고    scopus 로고
    • Depressed renal and vascular nitric oxide synthase expression in cyclosporine-induced hypertension
    • Vaziri N.D., Ni Z., Zhang Y.P., Ruzics E.P., Maleki P., Ding Y. Depressed renal and vascular nitric oxide synthase expression in cyclosporine-induced hypertension. Kidney Int. (1998) 54 482-491.
    • (1998) Kidney Int. , vol.54 , pp. 482-491
    • Vaziri, N.D.1    Ni, Z.2    Zhang, Y.P.3    Ruzics, E.P.4    Maleki, P.5    Ding, Y.6
  • 41
    • 0025910272 scopus 로고
    • Cyclosporin treatment does not impair the release of nitric oxide in human coronary arteries
    • O'Neil G.S., Chester A.H., Kushwaha S., Rose M., Tadjkarimi S., Yacoub M.H. Cyclosporin treatment does not impair the release of nitric oxide in human coronary arteries. Br. Heart J. (1991) 66 212-216.
    • (1991) Br. Heart J. , vol.66 , pp. 212-216
    • O'Neil, G.S.1    Chester, A.H.2    Kushwaha, S.3    Rose, M.4    Tadjkarimi, S.5    Yacoub, M.H.6
  • 42
    • 0027931645 scopus 로고
    • Role of nitric oxide in renal hemodynamic abnormalities of cyclosporin nephrotoxicity
    • Bobadilla N.A., Tapia E., Franco M. et al. Role of nitric oxide in renal hemodynamic abnormalities of cyclosporin nephrotoxicity. Kidney Int. (1994) 46 773-779.
    • (1994) Kidney Int. , vol.46 , pp. 773-779
    • Bobadilla, N.A.1    Tapia, E.2    Franco, M.3
  • 43
    • 0032785920 scopus 로고    scopus 로고
    • Effects of nitric oxide blockade and cyclosporin A on cardiovascular and renal function in normal man
    • Hansen J.M., Johansen N.J., Mollerup H.M., Anderson N.F., Strandgaard S. Effects of nitric oxide blockade and cyclosporin A on cardiovascular and renal function in normal man. J. Hypertens. (1999) 17 1707-1713.
    • (1999) J. Hypertens. , vol.17 , pp. 1707-1713
    • Hansen, J.M.1    Johansen, N.J.2    Mollerup, H.M.3    Anderson, N.F.4    Strandgaard, S.5
  • 44
    • 0030975237 scopus 로고    scopus 로고
    • L-arginine and allopurinol protect against cyclosporine nephrotoxicity
    • Assis S.M., Monteiro J.L., Seguro A.C. L-arginine and allopurinol protect against cyclosporine nephrotoxicity. Transplantation (1997) 63 1070-1073.
    • (1997) Transplantation , vol.63 , pp. 1070-1073
    • Assis, S.M.1    Monteiro, J.L.2    Seguro, A.C.3
  • 46
    • 0028223439 scopus 로고
    • Cyclosporine produces endothelial dysfunction by increased production of superoxide
    • Diederich D., Skopec J., Diederich A., Dai A. Cyclosporine produces endothelial dysfunction by increased production of superoxide. Hypertension (1994) 23 957-961.
    • (1994) Hypertension , vol.23 , pp. 957-961
    • Diederich, D.1    Skopec, J.2    Diederich, A.3    Dai, A.4
  • 49
    • 0023640470 scopus 로고
    • Nitroprusside-induced vascular relaxation is attenuated in organ-transplanted animals treated with cyclosporine
    • Huang H.C., Rego A., Vargas R., Foegh M.L., Ramwell P.W. Nitroprusside-induced vascular relaxation is attenuated in organ-transplanted animals treated with cyclosporine. Transplant. Proc. (1987) 19 126-130.
    • (1987) Transplant. Proc. , vol.19 , pp. 126-130
    • Huang, H.C.1    Rego, A.2    Vargas, R.3    Foegh, M.L.4    Ramwell, P.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.