Affinity extraction combined with stable isotope dilution LC/MS for the determination of 5-methyltetrahydrofolate in human plasma

Analytical Biochemistry

Volumn 313, Issue 1, 2003, Pages 117-127

  Nelson, Bryant C ^a   Pfeiffer, Christine M ^b   Margolis, Sam A ^a   Nelson, Chad P ^a  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

5 Methyltetrahydrofolate; Affinity extraction; Folate binding protein; Folates; Human plasma; Isotope dilution; Liquid chromatography; Mass Spectrometry

Indexed keywords

BINDING SITES; CALIBRATION; DRUG PRODUCTS; ISOTOPES; LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY; PLASMA (HUMAN); PLASMA DIAGNOSTICS; PLASMA STABILITY; POSITIVE IONS; PROTEINS;

5-METHYLTETRAHYDROFOLATE; AFFINITY EXTRACTION; FOLATE-BINDING PROTEIN; FOLATES; HUMAN PLASMAS; ISOTOPE DILUTIONS;

EXTRACTION;

5 METHYLTETRAHYDROFOLIC ACID; CARBON 13; FOLATE BINDING PROTEIN; PLASMA PROTEIN; POLYMER;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; BINDING SITE; BLOOD ANALYSIS; CALIBRATION; CATTLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; EXTRACTION; FOLIC ACID DEFICIENCY; HUMAN; IMMOBILIZATION; INTERMETHOD COMPARISON; ION MONITORING; ISOTOPE DILUTION ASSAY; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROBIOLOGY; PH; PLASMA; PRECIPITATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PRODUCT RECOVERY; PROTON TRANSPORT; QUANTITATIVE ANALYSIS; RADIOASSAY; ROOM TEMPERATURE; SOLID PHASE EXTRACTION; SPIKE; STANDARD;

BOS TAURUS; BOVINAE;

EID: 0037325815     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(02)00531-6     Document Type: Article

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