Pentacyclic triterpenoids from Embelia schimperi

Phytochemistry

Volumn 62, Issue 4, 2003, Pages 573-577

  Machocho, Alex K ^a   Kiprono, Paul C ^b   Grinberg, Sarina ^c   Bittner, Shmuel ^c  

^a KENYATTA UNIVERSITY   (Kenya)

^b MOI UNIVERSITY   (Kenya)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Aegicerin; Antibacterial activity; Embelia schimperi; Embelinone; Myrsinaceae; Pentacyclic triterpenoids; Primulagenin A; Protoprimulagenin A; Schimperinone

Indexed keywords

3,16 DIOXO 13BETA:17 METHYLENEOXYOLEANANE; 3BETA HYDROXY 13BETA:17 METHYLENEOXY 16 OXOOLEANANE; 3BETA,16ALPHA DIHYDROXY 13BETA:17 METHYLENEOXYOLEANANE; 3BETA,16ALPHA,28 TRIHYDROXY 12 OLEANENE; 3BETA,28 DIHYDROXY 16 OXO 12 OLEANENE; ANTI INFECTIVE AGENTS; ANTIINFECTIVE AGENT; EMBELIA SCHIMPERI EXTRACT; FUSED HETEROCYCLIC RINGS; HETEROCYCLIC COMPOUNDS, BRIDGED RING; TRITERPENE; TRITERPENOID; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BARK; CHEMICAL STRUCTURE; CHEMISTRY; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG SYNTHESIS; EMBELIA; ISOLATION AND PURIFICATION; KENYA; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RHODOCOCCUS; SEPARATION TECHNIQUE;

ANTI-BACTERIAL AGENTS; EMBELIA; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HETEROCYCLIC COMPOUNDS, BRIDGED-RING; KENYA; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PLANT BARK; PLANTS, MEDICINAL; RHODOCOCCUS; TRITERPENES;

BACTERIA (MICROORGANISMS); EMBELIA; MYRSINACEAE; POSIBACTERIA; RHODOCOCCUS; RHODOCOCCUS SP.;

EID: 0037323246     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(02)00619-2     Document Type: Article

References (15)

1. Alam, M.S., Chopra, N., Ali, M., Niwa, M., 2000. Normethyl pentacyclic and lanostane-type triterpenes from Adiantum venustum. Phytochemistry 54, 215-220.
2. Arot, L.O.M., Williams, L.A.D., 1997. A flavonol glycoside from Embelia schimperi. Phytochemistry 44, 1397-1398.
3. Beerntje, H.J., 1994. Kenya Trees, Shrubs and Lianas. National Museum of Kenya, Nairobi.
4. Bhatnagar, S.S., Santapau, H., Desa, J.D.H., Maniar, A.C., Ghadially, N.C., Solomon, M.J., Yellore, S., Rao, T.N.S., 1961. Biological activity of Indian medicinal plants: antibacterial, antitubercular and antifungal action. Ind. J. Med. Res. 49, 799-813.
5. Boegh, H.O., Andreassen, J., Lemmich, J., 1996. Anthelmintic usage of extract of Embelia schimperi from Tanzania. J. Ethnopharmacol. 50, 35-42.
6. Hussein, G., Miyashiro, H., Nakamura, N., Hattori, M., Kakiuchi, N., Shimotohno, K., 2000. Inhibitory effects of Sudanese medicinal plant extracts on hepatitis C virus (HCV) protease. Phytother. Res. 14, 510-516.
7. Katagawa, I., Matsuda, A., Yosioka, I., 1972. Saponin and sapogenol. VII. Sapogenol constituents of five Primulaceous plants. Chem. Pharm. Bull. 20, 2226-2234.
8. Kohda, H., Takeda, O., Tanaka, S., 1989. Molluscicidal triterpenoidal saponin from Lysimachia sikokiana. Chem. Pharm. Bull. 37, 3304-3305.
9. Kokwaro, J.O., 1976. Medicinal Plants of East Africa. East Africa Literature Bureau, Nairobi.
10. 13C NMR spectra of pentacyclic triterpenoids - a complilation and some salient features. Phytochemistry 37, 1517-1575.
11. Midiwo, J.O., Arot, L.M., 1993. Polynuclear acetogenic pigments in the fruits of the Myrsinaceae. Int. J. Bio. Chem. Phys. 2, 115-116.
12. Midiwo, J.O., Arot, L.M., Mbakaya, C.L., 1988. Distribution of benzoquinone pigments in Kenyan Myrsinaceae. Bull. Chem. Soc. Ethiop. 2, 83-85.
13. Ohtani, K., Mavi, S., Hostettmann, K., 1993. Molluscicidal and antifungal triterpenoid saponins from Rapanea melanophloeos leaves. Phytochemistry 33, 83-86.
14. Quijano, L., Rios, T., Fronczek, F.R., Fischer, N.H., 1998. The molecular structure of maniladiol from Baccharis saiicina. Phytochemistry 49, 2065-2068.
15. Rao, K.V., 1964. Chemistry of Aegiceras majus Gaertn V - structure of the triterpene aegicerin. Tetrahedron 20, 973-977.