Prolonged high-dose phosphate treatment: A risk factor for tertiary hyperparathyroidism in X-linked hypophosphatemic rickets

Clinical Endocrinology

Volumn 58, Issue 2, 2003, Pages 163-168

  Mäkitie, Outi ^a   Kooh, Sang Whay ^a   Sochett, Etienne ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CALCITRIOL; CALCIUM; PARATHYROID HORMONE; PHOSPHATE;

ADOLESCENT; ARTICLE; BONE MINERALIZATION; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DRUG MEGADOSE; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HORMONE BLOOD LEVEL; HUMAN; HYPERCALCEMIA; HYPERCALCIURIA; HYPERPARATHYROIDISM; HYPOPHOSPHATEMIA; INFANT; KIDNEY CALCIFICATION; LONG TERM CARE; MALE; ONSET AGE; PARATHYROID FUNCTION; PATIENT COMPLIANCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; TIME SERIES ANALYSIS; TREATMENT OUTCOME; VITAMIN D RESISTANT RICKETS; X CHROMOSOME LINKED DISORDER;

ADMINISTRATION, ORAL; ADOLESCENT; AGE OF ONSET; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERPARATHYROIDISM, SECONDARY; HYPOPHOSPHATEMIA, FAMILIAL; INFANT; MALE; PHOSPHATES;

EID: 0037322690     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2003.01685.x     Document Type: Article

References (27)

1. Albright, F., Butler, A.M. & Bloom, E. (1937) Rickets resistant to vitamin D therapy. American Journal of Diseases of Children, 54, 529-544.
2. Alon, U., Lovell, H.B. & Donaldson, D.L. (1992) Nephrocalcinosis, hyperparathyroidism, and renal failure in familial hypophosphatemic rickets. Clinical Pediatrics, 31, 180-183.
3. Arnaud, C., Glorieux, F. & Scriver, C. (1971) Serum parathyroid hormone in X-linked hypophosphatemia. Science, 173, 845-847.
4. Bettinelli, A., Bianchi, M.L., Mazzucchi, E., Gandolini, G. & Appiani, A.C. (1991) Acute effects of calcitriol and phosphate salts on mineral metabolism in children with hypophosphatemic rickets. Journal of Pediatrics, 118, 372-376.
5. Carpenter, T.O., Mitnick, M.A., Ellison, A., Smith, C. & Insogna, K.L. (1994) Nocturnal hyperparathyroidism: a frequent feature of X-linked hypophosphatemia. Journal of Clinical Endocrinology and Metabolism, 78, 1378-1383.
6. Chan, J.C.M., Alon, U. & Hirshman, G.M. (1985) Renal hypophosphatemic rickets. Journal of Pediatrics, 106, 533-544.
7. Chertow, B.D., Baylink, D.J., Wergedal, J.E., Su, M.H. & Norman, A.W. (1975) Decrease in serum immunoreactive parathyroid hormone in rats and in parathyroid hormone secretion in vitro by 1,25-dihydroxycholecalciferol. Journal of Clinical Investigation, 56, 668-678.
8. Drueke, T.B. (2001) Genetic aspects of secondary hyperparathyroidism in uremia. American Journal of Kidney Diseases, 38, S143-S146.
9. Forsberg, L., Villablanca, A., Välimäki, S., Farnebo, F., Farnebo, L.O., Lagercrantz, S. & Larsson, C. (2001) Homozygous inactivation of the MEN1 gene as a specific somatic event in a case of secondary hyperparathyroidism. European Journal of Endocrinology, 145, 415-420.
10. Friedman, N.E., Lobaugh, B. & Drezner, M.K. (1993) Effects of calcitriol and phosphorus therapy on the growth of patients with X-linked hypophosphatemia. Journal of Clinical Endocrinology and Metabolism, 76, 839-844.
11. Glorieux, F.H., Scriver, C.R., Reade, T.M., Goldman, H. & Roseborough, A. (1972) Use of phosphate and vitamin D to prevent dwarfism and rickets in X-linked hypophosphatemia. New England Journal of Medicine, 287, 481-487.
12. Glorieux, F.H., Marie, P.J., Pettifor, J.M. & Devlin, E.E. (1980) Bone response to phosphate salts, ergocalciferol, and calcitriol in familial hypophosphatemic rickets. New England Journal of Medicine, 303, 1023-1031.
13. Harrell, R.M., Lyles, K.W., Harrelson, J.M., Friedman, N.E. & Drezner, M.K. (1985) Healing of bone disease in X-linked hypophosphatemic rickets/osteomalacia. Induction and maintenance with phosphorus and calcitriol. Journal of Clinical Invesagation, 75, 1858-1868.
14. Kilav, R., Silver, J. & Nahev-Many, T. (1995) Parathyroid hormone gene expression in hypophosphatemic rats. Journal of Clinical Investigation, 96, 317-333.
15. Martin, K.J. & Gonzalez, E.A. (2001) Vitamin D analogues for the management of secondary hyperparathyroidism. American Journal of Kidney Diseases, 38, S34-S40.
16. Nemeth, E.F. & Fox, J. (1999) Calcimimetic compounds: a direct approach to controlling plasma levels of parathyroid hormone in hyperparathyroidism. Trends in Endocrinology and Metabolism, 10, 66-71.
17. 3 by phosphorus in normal men. Journal of Clinical Investigation, 83, 1494-1499.
18. Reitz, R.E. & Weinstein, R.L. (1973) Parathyroid hormone secretion in familial vitamin-D-resistant rickets. New England Journal of Medicine, 289, 941-945.
19. Rivkees, S.A., El-Hajj-Fuleihan, G., Brown, E.M. & Crawford, J.D. (1992) Tertiary hyperparathyroidism during high phosphate therapy of familial hypophosphatemic rickets. Journal of Clinical Endocrinology and Metabolism, 75, 1514-1518.
20. Russell, J., Lettieri, D. & Sherwood, L.M. (1986) Suppression by 1,25-(OH) D of transcription of the parathyroid hormone gene. Endocrinology, 119, 2864-2866.
21. Sato, K., Obara, T., Yamazaki, K., Kanbe, M., Nakajima, K., Yamada, A, Yanagisawa, T., Kato, Y., Nishikawa, T. & Takano, K. (2001) Somatic mutations of the MEN1 gene and microsatellite instability in a case of tertiary hyperparathyroidism occurring during high phosphate therapy for acquired, hypophosphatemic osteomalacia. Journal of Clinical Endocrinology and Metabolism, 86, 5564-5571.
22. Silver, J., Naveh-Many, T., Mayer, H., Schmelzer, H.J. & Popovtzer, M.M. (1986) Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat. Journal of Clinical Investigation, 78, 1296-1301.
23. Slatopolsky, E., Finch, J., Denda, M., Ritter, C., Zhong, M., Dusso, A., MacDonald, P.N. & Brown, A.J. (1996) Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro. Journal of Clinical Investigation, 97, 2534-2540.
24. The Hyp Consortium (1995) A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nature Genetics, 11, 130-136.
25. Verge, C.F., Lam, A., Simpson, J.M., Cowell, C.T., Howard, N.J. & Silink, M. (1991) Effects of therapy in X-linked hypophosphatemic rickets. New England Journal of Medicine, 325, 1843-1848.
26. Wu, C.J., Song, Y.M. & Sheu, W.H. (2000) Tertiary hyperparathyroidism in X-linked hypophosphatemic rickets. Internal Medicine, 39, 468-471.
27. Yi, H., Fukagawa, M., Yamato, H., Kumagai, M., Watanabe, T. & Kurokawa, K. (1995) Prevention of enhanced parathyroid hormone secretion, synthesis and hyperplasia by mild dietary phosphorus restriction in early chronic renal failure in rats: possible direct role of phosphorus. Nephron, 70, 242-248.