The risk of thrombolysis in association with cardiopulmonary resuscitation: No reason to withhold this causal and effective therapy

Journal of Internal Medicine

Volumn 253, Issue 2, 2003, Pages 99-101

  Böttiger, Bernd W ^a   Spohr F ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; FIBRINOLYTIC AGENT;

ACUTE HEART INFARCTION; BLEEDING; BRAIN HEMORRHAGE; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CORONARY ARTERY DISEASE; DRUG EFFICACY; DRUG SAFETY; EDITORIAL; EPISTAXIS; FIBRINOLYTIC THERAPY; GASTROINTESTINAL HEMORRHAGE; HEART ARREST; HEMATOMA; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PRIORITY JOURNAL; RESUSCITATION; STROKE; TRANSLUMINAL CORONARY ANGIOPLASTY; TREATMENT OUTCOME;

CARDIOPULMONARY RESUSCITATION; HUMANS; MYOCARDIAL INFARCTION; RISK FACTORS; THROMBOLYTIC THERAPY;

EID: 0037322090     PISSN: 09546820     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2796.2003.01106.x     Document Type: Editorial

References (27)

1. Fibrinolytic Therapy Trialists' (FTT) Collaborative Group. Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Lancet 1994; 343: 311-22.
2. Silfvast T. Cause of death in unsuccessful prehospital resuscitation. J Int Med 1991; 229: 331-5.
3. Spaulding CM, Joly LM, Rosenberg A et al. Immediate coronary angiography in survivers of out-of-hospital cardiac arrest. N Engl J Med 1997; 336: 1629-33.
4. Wilcox RG, von der Lippe G, Olsson CG, Jensen G, Skene AM, Hampton JR. Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction. Anglo-Scandanavian Study of Early Thrombolysis (ASSET). Lancet 1988; 2: 525-30.
5. Zipes DP, Wellens HJ. Sudden cardiac death. Circulation 1998; 98: 2334-51.
6. Curzen N, Haque R, Timmis A. Applications of thrombolytic therapy. Intensive Care Med 1998; 24: 756-68.
7. Ryan TJ, Antman EM, Brooks NH et al. ACC/AHA guidelines for the management of patients with acute myocardial infarction: executive summary and recommendations. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). Circulation 1999; 100: 1016-30.
8. The Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology. Acute myocardial infarction: pre-hospital and in-hospital management. Eur Heart J 1996; 17: 43-63.
9. Böttiger BW, Martin E. Thrombolytic therapy during cardiopulmonary resuscitation and the role of coagulation activation after cardiac arrest. Current Opinion Crit Care 2001; 7: 176-83.
10. Spöhr F, Böttiger BW. Safety of thrombolysis during cardiopulmonary resuscitation. Drug Saf 2003 (in press).
11. Abu-Laban RB, Christenson JM, Innes GD et al. Tissue plasminogen activator in cardiac arrest with pulseless electrical activity. N Engl J Med 2002; 346: 1522-8.
12. Böttiger BW, Bode C, Kern S et al. Efficacy and safety of thrombolytic therapy after initially unsuccessful cardiopulmonary resuscitation: a prospective clinical trial. Lancet 2001; 357: 1583-5.
13. Lederer W, Lichtenberger C, Pechlaner C, Kroesen G, Baubin M. Recombinant tissue plasminogen activator during cardiopulmonary resuscitation in 108 patients with out-of-hospital cardiac arrest. Resuscitation 2001; 50: 71-6.
14. Newman DH, Greenwald I, Calleway CW. Cardiac arrest and the role of thrombolytic agents. Ann Emerg Med 2000; 35: 472-80.
15. Fischer M, Böttiger BW, Popov-Cenic S, Hossmann KA. Thrombolysis using plasminogen activator and heparin reduces cerebral no-reflow after resuscitation from cardiac arrest: an experimental study in the cat. Intensive Care Med 1996; 22: 1214-23.
16. Böttiger BW, Motsch J, Böhrer H et al. Activation of blood coagulation after cardiac arrest is not balanced adequately by activation of endogenous fibrinolysis. Circulation 1995; 92: 2572-8.
17. Cross SJ, Lee HS, Rawles JM, Jennings K. Safety of thrombolysis in association with cardiopulmonary resuscitation. Br Med J 1991; 303: 1242.
18. Scholz KH, Tebbe U, Herrmann C et al. Frequency of complications of cardiopulmonary resuscitation after thrombolysis during acute myocardial infarction. Am J Cardiol 1992; 69: 724-8.
19. Tenaglia AN, Califf RM, Candela RJ et al. Thrombolytic therapy in patients requiring cardiopulmonary resuscitation. Am J Cardiol 1991; 68: 1015-9.
20. van Campen LC, van Leeuwen GR, Verheugt FW. Safety and efficacy of thrombolysis for acute myocardial infarction in patients with prolonged out-of hospital cardiopulmonary resuscitation. Am J Cardiol 1994; 73: 953-5.
21. Schiele R, Rustige J, Burcyk U et al. Thrombolysis after resuscitation in acute myocardial infarction. J Am Coll Cardiol 1996; 27(Suppl. A): 279A.
22. Stewart BF, Weaver WD, Parsons LS, Martin JS, Every NR. Reperfusion therapy after pre-hospital cardiac arrest and its influence on outcome after acute myocardial infarction. J Am Coll Cardiol 1996; 27(Suppl. A): 278A.
23. Ruiz-Bailen M, Aguayo de Hoyos E, Diaz-Castellanos MA. Role of thrombolysis in cardiac arrest. Intensive Care Med 2001; 27: 438-1.
24. Voipio V, Kuisma M, Alaspaa A, Manttari M, Rosenberg P. Thrombolytic treatment of acute myocardial infarction after out-of-hospital cardiac arrest. Resuscitation 2001; 49: 251-8.
25. Schreiber W, Gabriel D, Sterz F et al. Thrombolytic therapy after cardiac arrest and its effect on neurological outcome. Resuscitation 2002; 52: 63-9.
26. Böttiger BW, Padosch SA, Wenzel V. Tissue plasminogen activator in cardiac arrest with pulseless electrical activity. N Engl J Med 2002; 347: 1281-2.
27. Kurkciyan I, Meron G, Sterz F et al. Major bleeding complications after cardiopulmonary resuscitation: impact of thrombolytic treatment. J Intern Med 2003; 253: 128-135.