Acidic nonsteroidal anti-inflammatory drugs inhibit rat brain fatty acid amide hydrolase in a pH-dependent manner

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 18, Issue 1, 2003, Pages 55-58

  Fowler, Christopher J ^a   Holt, Sandra ^a   Tiger, Gunnar ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

Anandamide; Celecoxib; Fatty acid amide hydrolase; Flurbiprofen; Ibuprofen; Indomethacin; Niflumic acid; Non steroidal anti inflammatory agents

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; AMIDE; AMINO ACID; ANANDAMIDE; CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; FLURBIPROFEN; HYDROLASE; HYDROLASE INHIBITOR; IBUPROFEN; INDOMETACIN; NIFLUMIC ACID; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; TRITIUM;

ACIDITY; AMINO ACID BRAIN LEVEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME METABOLISM; IC 50; IONIZATION; NONHUMAN; PH; PRIORITY JOURNAL; RAT;

AMIDOHYDROLASES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRAIN; HYDROGEN-ION CONCENTRATION; RATS;

ANIMALIA; TRITIUM;

EID: 0037320223     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/1475636021000049726     Document Type: Article

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