Inhibitory effect of IRES specific inhibitor RNA on HCV IRES mediated protein translation

World Chinese Journal of Digestology

Volumn 11, Issue 2, 2003, Pages 157-160

  Liang, Xue Song ^a   Lian, Jian Qi ^a   Zhou, Yong Xing ^a   Nie, Qin He ^a   Hao, Chun Qui ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; RNA;

ARTICLE; DNA VECTOR; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSFECTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; MUTANT; NONHUMAN; RNA TRANSLATION;

EID: 0037319337     PISSN: 10093079     EISSN: None     Source Type: Journal    
DOI: 10.11569/wcjd.v11.i2.157     Document Type: Article

References (40)

1. Rabe C, Pilz T, Klostermann C, Berna M, Schild HH, Sauerbruch T, Caselmann WH. Clinical characteristics and outcome of a cohort of 101 patients with hepatocellular carcinoma. World J Gastroenterol 2001;7:208-215
2. Huang F, Zhao GZ, Li Y. HCV genotypes in hepatitis C patients and their clinical significances. World J Gastroenterol 1999;5:547-549
3. Chen MY, Huang ZQ, Chen LZ, Gao YB, Peng RY, Wang DW. Detection of hepatitis C virus NS5 protein and genome in Chinese carcinoma of the extrahepatic bile duct and its significance. World J Gastroenterol 2000;6:800-804
4. Yan J, Dennin RH. A high frequency of GBV-C/HGV coinfection in hepatitis C patients in Germany. World J Gastroenterol 2000;6:833-841
5. Wang NS, Liao LT, Zhu YJ. Follow-up study of hepatitis C virus infection in uremic patients on maintenance hemodialysis for 30 months. World J Gastroenterol 2000;6:888-892
6. Worman HJ, Lin F. Molecular biology of liver disorders: the hepatitis C virus and molecular targets for drug development. World J Gastroenterol 2000;6:465-469
7. Song ZQ, Hao F, Min F, Ma QY, Liu GD. Hepatitis C virus infection of human hepatoma cell line 7721 in vitro. World J Gastroenterol 2001;7:685-689
8. Zhou HC, Xu DZ, Wang XP, Zhang JX, Huang Y, Yan YP, Zhu Y, Jin BQ. Identification of the epitopes on HCV core protein recognized by HLA-A2 restricted cytotoxic T lymphocytes. World J Gastroenterol 2001;7:583-586
9. Cheng JL, Tong WB, Liu BL, Zhang Y, Yan Z, Feng BF. Hepatitis C virus in human B lymphocytes transformed by Epstein-Barr virus in vitro by in situ reverse transcriptase-polymerase chain reaction. World J Gastroenterol 2001;7:370-375
10. Meier V, Mihm S, Wietzke-Braun P, Ramadori G. HCV-RNA positivity in peripheral blood mononuclear cells of patients with chronic HCV-infection: does it really mean viral replication? World J Gastroenterol 2001;7:228-234
11. Rabe C, Pilz T, Klostermann C, Berna M, Schild HH, Sauerbnuch T, Caselann WH. Clinical characteristics and outcome of a cohort of 101 patients with hepatocellular carcinoma. World J Gastroenterol 2001;15;7:208-215
12. Yan FM, Chen AS, Hao F, Zhao XP, Gu CH, Zhao LB, Yang DL, Hao LJ. Hepatitis C virus may infect extrahepatic tissues in patients with hepatitis C. World J Gastroenterol 2000;6:805-811
13. Woitas RP, Petersen U, Moshage D, Brackmann HH, Matz B, Sauerbruch T, Spengler U. HCV-specific cytokine induction in monocytes of patients with different outcomes of hepatitis C. World J Gastroenterol 2002;8:562-566
14. Jin J, Yang JY, Liu J, Kong YY, Wang Y, Li GD. DNA immunization with fusion genes encoding different regions of hepatitis C vir us E2 fused to the gene for hepatitis B surface antigen elicits immune responses to both HCV and HBV. World J Gastroenterol 2002;8:505-510
15. Zhu LX, Liu J, Li YC, Kong YY, Staib C, Sutter G, Wang Y, Li GD. Full-length core sequence dependent complex-type glycosylation of hepatitis C virus E2 glycoprotein. World J Gastroenterol 2002;8:499-504
16. Jiang RL, Lu QS, Luo KX. Cloning and expression of core gene cDNA of Chinese hepatitis C virus in cosmid pTM3. World J Gastroenterol 2000;6:220-222
17. Yang SS, Wu CH, Chen TH, Huang YY, Huang CS. TT viralinfection through blood transfusion: retrospective investigation on patients in a prospective study of post transfusion hepatitis. World J Gastroenterol 2000;6:70-73
18. Yu YC, Mao Q, Gu CH, Li QF, Wang YM. Activity of HDV ribozymes to trans-cleave HCV RNA. World J Gastroenterol 2002;8:694-698
19. Tang ZY. Hepatocellular carcinoma cause, treatment and metastasis. World J Gastroenterol 2001;7:445-454
20. Assy N, Paizi M, Gaitini D, Baruch Y, Spira G. Clinical implication of VEGF serum levels in cirrhotic patients with or without portal hypertension. World J Gastroenterol 1999;5:296-300
21. Zhang SZ, Liang JJ, Qi ZT, Hu YP. Cloning of the non-structural gene 3 of hepatitis C virus and its inducible expression in cultured cells. World J Gastroenterol 1999;5:125-127
22. Assy N, Minuk GY. A comparison between previous and present histologic assessments of chronic hepatitis C viral infections in humans. World J Gastroenterol 1999;5:107-110
23. Feng DY, Chen RX, Peng Y, Zheng H, Yan YH. Effect of HCV NS3 protein on p53 protein expression in hepatocarcinogenesis. World J Gastroenterol 1999;5:45-46
24. Yang JM, Wang RQ, Bu BG, Zhou ZC, Fang DC, Luo YH. Effect of HCV infection on expression of several cancer-associated gene products in HCC. World J Gastroenterol 1999;5:25-27
25. Maier I, Wu GY. Hepatitis C and HIV co-infection: a review. World J Gastroenterol 2002;8:577-579
26. Scheiflinger F, Dorner F. Recent advances in the understanding of the molecular biology of hemophilia A: possible implications towards a more effective therapeutic regime. Wien Klin Wochenschr 1999;111:172-180
27. Fang J, Edwin O. Transfection and expression of HCV-NS(5)B gene in Huh-7 cells Zhonghua Ganzangbing Zazhi 2000;8:33-34
28. Kolarski V. The European consensus on hepatitis C. Vutr Boles 1999;31:21-28
29. Fang J, Ouyang E, Wu CH, Wu GY, Qiu D, Xiao S. Transfection and expression of HCV-NS5B gene in Huh-7 cells. Chin Med J (Engl) 2000;113:602-605
30. Wang QM, Heinz BA. Rescent advances in prevention and treatment of hepatitis C virus infections. Prog Drug Res 2001;79-110
31. Odreman -Macchioli F, Baralle FE, Buratti E. Mutational analysis of the different bulge regions of hepatitis C virus domain II and their influence on internal ribosome entry site translation abibility. J Biol Chem 2001;276:41648-416455
32. Jubin R, Vantuno NE, Kieft JS, Murray MG, Doudna JA, Lau JY, Baroudy BM. Hepatitis C virus internal ribosome entry site(IRES) stem loop IIId contains a phylogenetically conserved GGG triple essential for translation and IRES folding. J Virol 2000;77:10430-10437
33. Macejak DG, Jensen KL, Jamison SF, Domenico K, Roberts EC, Chaudhary N, von Carlowitz I, Bellon L, Tong MJ, Conrad A, Pavco PA, Blatt LM. Inhibition of hepatitis C virus RNA dependent translation and replication of a chimeric HCV poliovirus using sunthetic stabilized ribozymes. Hepatology 2000;31:769-776
34. Collier AJ, Gallego J, Klinck R, Cole PT, Harris SJ, Harrison GP, Aboul-Ela F, Varani G, Walker S. A conserved RNA structure within the HCV IRES eIF3-binding site. Nat Struct Biol 2002;9:375-380
35. Friebe P, Lohmann V, Krieger N, Bartenschlager R. Sequence in the 5′ nontranslated region of hepatitis C virus required for RNA replication. J Virol 2001;75:12047-12057
36. Wiklund L, Spangberg K, Goobar-Larsson L, Schwartz S. Cap and poly A tail enhance translation initiation at the hepatitis C virus internal ribosome entry site by a discontinuous scanning, or shunting machenism. J Hum Virol 2001;4:74-84
37. Zhang H, Hanecak R, Brown-Driver V, Azad R, Conklin B, Fox MC, Anderson KP. Antisense oligonucleotide inhibition of hepatitis C virus gene expression in livers of mice infected with an HCV-vaccinia virus recombinant. Antimicro Agents Chemother 1999;43:347-353
38. Lukavsky PJ, Otto GA, Lancaster AM, Sarnow P, Puglisi JD. Structures of two RNA domains essential for hepatitis C virus internal ribosomeentry site function. Nat Struct Biol 2000;7:1105-1110
39. Izumi RE, Valdez B, Banerjee R, Srivastava M, Dasgupta A. Nucleolin stimulates viral internal ribosome entry site-mediated translation. Virus Res 2001;76:17-29
40. Venkatesan A, Das S, Dasgupta A. Structuer and function of a small RNA that selectively inhibits internal ribosome entry site-mediated translation. Proc Nucle Acid Res USA 1999;27:563-572