Synthesis of 3,3′-(1-piperidino)substituted methylene-bis-isoxazoles preventing stimulus-induced leukocytes activation

Farmaco

Volumn 58, Issue 2, 2003, Pages 121-127

  Mazzei, M ^a   Nieddu, E ^a   Melloni, E ^a   Minafra, R ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

3,3 (1 Piperidino) substituted methylene bis isoxazoles; Ischemia; Mannich bases; Neutrophils; Reperfusion injuries; Superoxide anion

Indexed keywords

3,3' METHYLENBIS[2 (1 PIPERIDINYL) 7 METHOXYCHROMONE]; 4,4' METHYLENBIS[3 (1 PIPERIDINYL) 5 (2 ACETOXY 4 METHOXYPHENYL)ISOXAZOLE]; 4,4' METHYLENBIS[3 (1 PIPERIDINYL) 5 (2 ETHOXY 4 METHOXYPHENYL)ISOXAZOLE]; 4,4' METHYLENBIS[3 (1 PIPERIDINYL) 5 (2 HYDROXY 4 METHOXYPHENYL)ISOXAZOLE]; 4,4' METHYLENBIS[3 (1 PIPERIDINYL) 5 (2 PROPYLOXY 4 METHOXYPHENYL)ISOXAZOLE]; 4,4' METHYLENBIS[3 (1 PIPERIDINYL) 5 (2,4 DIMETHOXYPHENYL)ISOXAZOLE]; 4,4' METHYLENBIS[3 (1 PIPERIDINYL) 5 [2 (2 N,N DIETHYLAMINOETHOXY) 4 METHOXYPHENYL]ISOXAZOLE]; FORMYLMETHIONYLLEUCYLPHENYLALANINE; ISOXAZOLE DERIVATIVE; MANNICH BASE; N,N' [[2 (PIPERIDINYL) 7 METHOXYCHROMON 3 YL]METHYL]PIPERAZINE; PHORBOL 13 ACETATE 12 MYRISTATE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL STIMULATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; LEUKOCYTE; NEUTROPHIL;

HUMANS; HYDROCARBONS; ISOXAZOLES; LEUKOCYTES; METHANE; PIPERIDINES;

EID: 0037318862     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(02)00008-3     Document Type: Article

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