Simulating haplotype blocks in the human genome

Bioinformatics

Volumn 19, Issue 2, 2003, Pages 289-290

  Posada, David ^a   Wiuf, Carsten ^a  

^a Variagenics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOINFORMATICS; COMPUTER PROGRAM; COMPUTER SIMULATION; DEMOGRAPHY; GENE MUTATION; GENE STRUCTURE; GENETIC ASSOCIATION; GENETIC RECOMBINATION; HAPLOTYPE; HUMAN; HUMAN GENOME; PRIORITY JOURNAL; SAMPLE;

EID: 0037314075     PISSN: 13674803     EISSN: 13674811     Source Type: Journal    
DOI: 10.1093/bioinformatics/19.2.289     Document Type: Article

References (8)

1. Daly,M.J. et al. (2001) High-resolution haplotype structure in the human genome. Nature Genet., 29, 229-232.
2. Gabriel,S.B. et al. (2002) The structure of haplotype blocks in the human genome. Science, 23, 23.
3. Hudson,R.R. (1983) Properties of a neutral allele model with intragenic recombination. Theor. Popul. Biol., 23, 183-201.
4. Hudson,R.R. (2002) Generating samples under a Wright-Fisher neutral model of genetic variation. Bioinformatics, 18, 337-338.
5. Jeffreys,A.J., Kauppi,L. and Neumann,R. (2001) Intensively punctuated meiotic recombination in the class II region of the major histocompatibility complex. Nature Genet., 29, 217-222.
6. Johnson.G.C. et al. (2001) Haplotype tagging for the identification of common disease genes. Nature Genet., 29, 233-237.
7. Jukes,T.H. and Cantor,C.R. (1969) In Munro,H.M. (ed.), Evolution of protein molecules, Mammalian Protein Metabolism, Academic Press, New York, pp. 21-132.
8. Patil,N. et al. (2001) Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science, 294, 1719-1723.