메뉴 건너뛰기




Volumn 131, Issue 2, 2003, Pages 217-224

Endogenous glucocorticoids attenuate Shiga toxin-2-induced toxicity in a mouse model of haemolytic uraemic syndrome

Author keywords

Glucocorticoid receptors; Glucocorticoids; HUS; Neutrophils; Stx2

Indexed keywords

BACTERIAL TOXIN; CORTICOSTERONE; CYTOKINE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 1BETA; SHIGA TOXIN; TUMOR NECROSIS FACTOR ALPHA; VEROTOXIN 2;

EID: 0037313994     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2003.02057.x     Document Type: Article
Times cited : (21)

References (51)
  • 1
    • 0029024101 scopus 로고
    • The hemolytic uremic syndrome
    • Remuzzi G, Ruggenenti P. The hemolytic uremic syndrome. Kidney Int 1995; 47:2-19.
    • (1995) Kidney Int , vol.47 , pp. 2-19
    • Remuzzi, G.1    Ruggenenti, P.2
  • 2
    • 0021325368 scopus 로고
    • Renal histopathology in the hemolytic uremic syndrome following shigellosis
    • Koster F, Boonpucknavig V, Sujaho S, Gilman R, Rahaman M. Renal histopathology in the hemolytic uremic syndrome following shigellosis. Clin Nephrol 1984; 21:126-33.
    • (1984) Clin Nephrol , vol.21 , pp. 126-133
    • Koster, F.1    Boonpucknavig, V.2    Sujaho, S.3    Gilman, R.4    Rahaman, M.5
  • 3
    • 0030901352 scopus 로고    scopus 로고
    • Association of verotoxin-producing E. coli and verotoxin with hemolytic uremic syndrome
    • Arbus GS. Association of verotoxin-producing E. coli and verotoxin with hemolytic uremic syndrome. Kidney Int 1997; 58: S91-6.
    • (1997) Kidney Int , vol.58
    • Arbus, G.S.1
  • 4
    • 0021946215 scopus 로고
    • The association between idiopathic uremic syndrome and infection by verotoxin-producing Escherichia coli
    • Karmali MA, Petric M, Lim C, Fleming PC, Arbus GS, Lior H. The association between idiopathic uremic syndrome and infection by verotoxin-producing Escherichia coli. J Infect Dis 1985; 151:775-82.
    • (1985) J Infect Dis , vol.151 , pp. 775-782
    • Karmali, M.A.1    Petric, M.2    Lim, C.3    Fleming, P.C.4    Arbus, G.S.5    Lior, H.6
  • 5
    • 0030948395 scopus 로고    scopus 로고
    • Thrombotic thrombocytopenic purpura associated with shiga toxins
    • Keusch GT, Acheson DWK. Thrombotic thrombocytopenic purpura associated with shiga toxins. Semin Hematol 1997; 34:106-16.
    • (1997) Semin Hematol , vol.34 , pp. 106-116
    • Keusch, G.T.1    Acheson, D.W.K.2
  • 6
    • 0031848112 scopus 로고    scopus 로고
    • Pathogenesis and diagnosis of shiga toxin-producing Escherichia coli infections
    • Paton JC, Paton AW. Pathogenesis and diagnosis of shiga toxin-producing Escherichia coli infections. Clin Microbiol Rev 1998; 11:450-79.
    • (1998) Clin Microbiol Rev , vol.11 , pp. 450-479
    • Paton, J.C.1    Paton, A.W.2
  • 9
    • 0344002719 scopus 로고    scopus 로고
    • Shiga toxin-2 induces neutrophilia and neutrophil activation in a murine model of hemolytic uremic syndrome
    • Fernández GC, Rubel C, Dran G, Gomez S, Isturiz MA, Palermo MS. Shiga toxin-2 induces neutrophilia and neutrophil activation in a murine model of hemolytic uremic syndrome. Clin Immunol 2000; 95:227-34.
    • (2000) Clin Immunol , vol.95 , pp. 227-234
    • Fernández, G.C.1    Rubel, C.2    Dran, G.3    Gomez, S.4    Isturiz, M.A.5    Palermo, M.S.6
  • 10
    • 0344061522 scopus 로고    scopus 로고
    • Characterization of the baboon responses to Shiga-like toxin: Descriptive study of a new primate model of toxic responses to Stx-1
    • Taylor FB Jr, Tesh VL, DeBault L et al. Characterization of the baboon responses to Shiga-like toxin: descriptive study of a new primate model of toxic responses to Stx-1. Am J Pathol 1999; 154:1285-99.
    • (1999) Am J Pathol , vol.154 , pp. 1285-1299
    • Taylor F.B., Jr.1    Tesh, V.L.2    DeBault, L.3
  • 11
    • 0025370411 scopus 로고
    • Mouse model for colonization and disease caused by enterohemorragic Escherichia coli O157:H7
    • Wadolkowski EA, Burris JA, O'Brien AD. Mouse model for colonization and disease caused by enterohemorragic Escherichia coli O157:H7. Infect Immun 1990; 58: 2438-45.
    • (1990) Infect Immun , vol.58 , pp. 2438-2445
    • Wadolkowski, E.A.1    Burris, J.A.2    O'Brien, A.D.3
  • 12
    • 0024582724 scopus 로고
    • Edema disease-like brain lesions in gnotobiotic piglets infected with Escherichia coli serotype O157:H7
    • Francis DH, Moxley RA, Andraos CY. Edema disease-like brain lesions in gnotobiotic piglets infected with Escherichia coli serotype O157:H7. Infect Immun 1989; 57: 1339-42.
    • (1989) Infect Immun , vol.57 , pp. 1339-1342
    • Francis, D.H.1    Moxley, R.A.2    Andraos, C.Y.3
  • 13
    • 0024434519 scopus 로고
    • Bacterial endotoxin both enhances and inhibits the toxicity of Shiga-like toxin II in rabbits and mice
    • Barret TJ, Potter ME, Wachsmuth K. Bacterial endotoxin both enhances and inhibits the toxicity of Shiga-like toxin II in rabbits and mice. Infect Immun 1989; 57:3434-7.
    • (1989) Infect Immun , vol.57 , pp. 3434-3437
    • Barret, T.J.1    Potter, M.E.2    Wachsmuth, K.3
  • 14
    • 0027363238 scopus 로고
    • A reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by shiga-like toxin
    • Harel Y, Silva M, Giroir B, Weinberg A, Cleary TB, Beutler B. A reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by shiga-like toxin. J Clin Invest 1993; 92:2110-6.
    • (1993) J Clin Invest , vol.92 , pp. 2110-2116
    • Harel, Y.1    Silva, M.2    Giroir, B.3    Weinberg, A.4    Cleary, T.B.5    Beutler, B.6
  • 15
    • 0033030437 scopus 로고    scopus 로고
    • Depletion of liver and splenic macrophages reduces the lethality of Shiga toxin-2 in a mouse model
    • Palermo MS, Alves Rosa MF, Van Rooijen N, Isturiz MA. Depletion of liver and splenic macrophages reduces the lethality of Shiga toxin-2 in a mouse model. Clin Exp Immunol 1999; 116:462-7.
    • (1999) Clin Exp Immunol , vol.116 , pp. 462-467
    • Palermo, M.S.1    Alves Rosa, M.F.2    Van Rooijen, N.3    Isturiz, M.A.4
  • 17
    • 0343953051 scopus 로고    scopus 로고
    • Binding and transfer of verocytotoxin by polymorphonuclear leukocytes in hemolytic uremic syndrome
    • Te Loo DMWM, Monnens LAH, van der Velden TJAM et al. Binding and transfer of verocytotoxin by polymorphonuclear leukocytes in hemolytic uremic syndrome. Blood 2000; 95:3396-402.
    • (2000) Blood , vol.95 , pp. 3396-3402
    • Te Loo, D.M.W.M.1    Monnens, L.A.H.2    Van Der Velden, T.J.A.M.3
  • 18
    • 0020332537 scopus 로고
    • Corticosteroid-mediated immunoregulation in man
    • Cupps TR, Fauci AS. Corticosteroid-mediated immunoregulation in man. Immunol Rev 1982; 65:133-53.
    • (1982) Immunol Rev , vol.65 , pp. 133-153
    • Cupps, T.R.1    Fauci, A.S.2
  • 19
    • 0029554927 scopus 로고
    • The protective role of the hypothalamic-pituitary-adrenal axis against lethality produced by immune, infectious and inflammatory stress
    • Kapcala LP, Chautard T, Reskay RL. The protective role of the hypothalamic-pituitary-adrenal axis against lethality produced by immune, infectious and inflammatory stress. Ann NY Acad Sci 1995; 771:419-37.
    • (1995) Ann NY Acad Sci , vol.771 , pp. 419-437
    • Kapcala, L.P.1    Chautard, T.2    Reskay, R.L.3
  • 20
    • 43949157849 scopus 로고
    • The syntax of immune-neuroendocrine communication
    • Blalock JE. The syntax of immune-neuroendocrine communication. Immunol Today 1985; 15:504-11.
    • (1985) Immunol Today , vol.15 , pp. 504-511
    • Blalock, J.E.1
  • 21
    • 0031196551 scopus 로고    scopus 로고
    • Effects of viral infection on corticosterone secretion and glucocorticoid receptor binding in immune tissues
    • Miller AH, Spencer RL, Pearce BD et al. Effects of viral infection on corticosterone secretion and glucocorticoid receptor binding in immune tissues. Psychoneuroendocrinology 1997; 22:455-74.
    • (1997) Psychoneuroendocrinology , vol.22 , pp. 455-474
    • Miller, A.H.1    Spencer, R.L.2    Pearce, B.D.3
  • 22
    • 23544438166 scopus 로고    scopus 로고
    • Cytokines mediate protective stimulation of glucocorticoid output during autoimmunity: Involvement of IL-1
    • Del Rey A, Klusman I, Besedovsky HO. Cytokines mediate protective stimulation of glucocorticoid output during autoimmunity: involvement of IL-1. Am J Physiol 1998; 275:R1146-51.
    • (1998) Am J Physiol , vol.275
    • Del Rey, A.1    Klusman, I.2    Besedovsky, H.O.3
  • 23
    • 0024534407 scopus 로고
    • Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids
    • MacPhee IAM, Antoni FA, Mason WD. Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids. J Exp Med 1989; 169:431-45.
    • (1989) J Exp Med , vol.169 , pp. 431-445
    • MacPhee, I.A.M.1    Antoni, F.A.2    Mason, W.D.3
  • 24
    • 0344239828 scopus 로고
    • Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis susceptible Lewis rats
    • Sternberg EM, Hill JM, Chrousos GP et al. Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis susceptible Lewis rats. Proc Natl Acad Sci USA 1989; 86:2374-8.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2374-2378
    • Sternberg, E.M.1    Hill, J.M.2    Chrousos, G.P.3
  • 25
    • 0033228361 scopus 로고    scopus 로고
    • Effect of cortisol-synthesis inhibition on endotoxin-induced porcine acute lung injury, shock and nitric oxide production
    • Middelveld RJ, Wanecek M, Bergman D, Weitzberg E, Alving K. Effect of cortisol-synthesis inhibition on endotoxin-induced porcine acute lung injury, shock and nitric oxide production. Shock 1999; 12:382-90.
    • (1999) Shock , vol.12 , pp. 382-390
    • Middelveld, R.J.1    Wanecek, M.2    Bergman, D.3    Weitzberg, E.4    Alving, K.5
  • 27
    • 0027399477 scopus 로고
    • A new kinetic single stage Limulus amoebocyte lysate method for the detection of endotoxin in water and plasma
    • Duner KI. A new kinetic single stage Limulus amoebocyte lysate method for the detection of endotoxin in water and plasma. J Biochem Biophys Meth 1993; 26:131-42.
    • (1993) J Biochem Biophys Meth , vol.26 , pp. 131-142
    • Duner, K.I.1
  • 28
    • 0031737799 scopus 로고    scopus 로고
    • Mechanism of suppressed neutrophil mobilization in a mouse model for binge drinking: Role of glucocorticoids
    • Vinson RB, Carroll JL, Pret SB. Mechanism of suppressed neutrophil mobilization in a mouse model for binge drinking: role of glucocorticoids. Am J Physiol 1998; 275:R1049-57.
    • (1998) Am J Physiol , vol.275
    • Vinson, R.B.1    Carroll, J.L.2    Pret, S.B.3
  • 29
    • 0033984719 scopus 로고    scopus 로고
    • Pretreatment of mice with LPS or IL-1β exerts opposite effects on Shiga-toxin-2 lethality
    • Palermo MS, Rubel C, Alves Rosa F et al. Pretreatment of mice with LPS or IL-1β exerts opposite effects on Shiga-toxin-2 lethality. Clin Exp Immunol 1999; 119:77-83.
    • (1999) Clin Exp Immunol , vol.119 , pp. 77-83
    • Palermo, M.S.1    Rubel, C.2    Alves Rosa, F.3
  • 30
    • 0013173129 scopus 로고
    • In vitro assays for mouse lymphocyte function
    • Coligan J, Knisblek A, Margulies D et al.,eds. National Institute of Health. USA: Wiley & Sons Inc.
    • Coligan J, Knisblek A, Margulies D, Shevach E, Warren S. In vitro assays for mouse lymphocyte function. In: Coligan J, Knisblek A, Margulies D et al., eds. Current protocols in mununology. National Institute of Health. USA: Wiley & Sons Inc., 1994:3.20.3-4.
    • (1994) Current Protocols in Mununology , pp. 3203-3204
    • Coligan, J.1    Knisblek, A.2    Margulies, D.3    Shevach, E.4    Warren, S.5
  • 31
    • 0028618803 scopus 로고
    • Flow cytometric analysis of cell surface and intracellular antigens in leukemia diagnosis
    • Knapp W, Majdic O, Strobl H. Flow cytometric analysis of cell surface and intracellular antigens in leukemia diagnosis. Cytometry 1994; 18:187-98.
    • (1994) Cytometry , vol.18 , pp. 187-198
    • Knapp, W.1    Majdic, O.2    Strobl, H.3
  • 32
    • 0032565612 scopus 로고    scopus 로고
    • Glucocorticoid receptors are differentially expressed in the cells and tissues of the immune system
    • Miller AH, Spencer RL, Pearce BD et al. Glucocorticoid receptors are differentially expressed in the cells and tissues of the immune system. Cell Immunol 1998; 186:45-54.
    • (1998) Cell Immunol , vol.186 , pp. 45-54
    • Miller, A.H.1    Spencer, R.L.2    Pearce, B.D.3
  • 33
    • 0025370394 scopus 로고
    • Inhibition of macrophage differentiation and function by cortisol
    • Baybutt HN, Holsboer NJ. Inhibition of macrophage differentiation and function by cortisol. Endocrinology 1990; 127:476-80.
    • (1990) Endocrinology , vol.127 , pp. 476-480
    • Baybutt, H.N.1    Holsboer, N.J.2
  • 34
    • 0025169732 scopus 로고
    • Evidence that glucocorticoids block expression of the human interleukin-6 gene by accessory cells
    • Zanker B, Walz G, Wleder J, Strom TB. Evidence that glucocorticoids block expression of the human interleukin-6 gene by accessory cells. Transplantation 1990; 49:183-5.
    • (1990) Transplantation , vol.49 , pp. 183-185
    • Zanker, B.1    Walz, G.2    Wleder, J.3    Strom, T.B.4
  • 35
    • 0019904008 scopus 로고
    • Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production
    • Snyder DS, Unanue ER. Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production. J Immunol 1982; 129:1803-5.
    • (1982) J Immunol , vol.129 , pp. 1803-1805
    • Snyder, D.S.1    Unanue, E.R.2
  • 36
    • 0029164394 scopus 로고
    • Role of hypothalamus-pituitary-adrenal axis in the regulation of TNF production in mice
    • Fantuzi G, Di Santo E, Sacco S, Benigni F, Ghezzi P. Role of hypothalamus-pituitary-adrenal axis in the regulation of TNF production in mice. J Immunol 1995; 155:3552-5.
    • (1995) J Immunol , vol.155 , pp. 3552-3555
    • Fantuzi, G.1    Di Santo, E.2    Sacco, S.3    Benigni, F.4    Ghezzi, P.5
  • 37
    • 0028835139 scopus 로고
    • Pulse methyl-prednisolone in rheumatoid arthritis: Effects on peripheral blood and synovial fluid neutrophil surface phenotype
    • Youssef P, Roberts-Thomson P, Ahern M, Smith M. Pulse methyl-prednisolone in rheumatoid arthritis: effects on peripheral blood and synovial fluid neutrophil surface phenotype. J Rheumatol 1995; 22:2065-71.
    • (1995) J Rheumatol , vol.22 , pp. 2065-2071
    • Youssef, P.1    Roberts-Thomson, P.2    Ahern, M.3    Smith, M.4
  • 38
    • 0031727193 scopus 로고    scopus 로고
    • Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation
    • Goulding NJ, Euzger HS, Butt SK, Perretti M. Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation. Inflamm Res 1998; 47:S158-65.
    • (1998) Inflamm Res , vol.47
    • Goulding, N.J.1    Euzger, H.S.2    Butt, S.K.3    Perretti, M.4
  • 39
    • 0033017131 scopus 로고    scopus 로고
    • Glucocorticoid hormone suppression of human neutrophil-mediated tumor cell cytostasis
    • Yazawa H, Kato T, Nakata T, Sendo F. Glucocorticoid hormone suppression of human neutrophil-mediated tumor cell cytostasis. Int J Cancer 1999; 81:74-80.
    • (1999) Int J Cancer , vol.81 , pp. 74-80
    • Yazawa, H.1    Kato, T.2    Nakata, T.3    Sendo, F.4
  • 40
    • 0033856297 scopus 로고    scopus 로고
    • Shiga toxin-induced tumor necrosis factor alpha expression: Requirement for toxin enzymatic activity and monocyte protein kinase C and protein tyrosine kinases
    • Foster GH, Armstrong CS, Sakiri R, Tesh VL. Shiga toxin-induced tumor necrosis factor alpha expression: requirement for toxin enzymatic activity and monocyte protein kinase C and protein tyrosine kinases. Infect Immun 2000; 68:5183-9.
    • (2000) Infect Immun , vol.68 , pp. 5183-5189
    • Foster, G.H.1    Armstrong, C.S.2    Sakiri, R.3    Tesh, V.L.4
  • 41
    • 0023922510 scopus 로고
    • Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor
    • Bertini R, Bianchi M, Ghezzi P. Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor. J Exp Med 1988; 167:1708-12.
    • (1988) J Exp Med , vol.167 , pp. 1708-1712
    • Bertini, R.1    Bianchi, M.2    Ghezzi, P.3
  • 42
    • 0024460625 scopus 로고
    • Neuroendocrine regulation of in vivo cytokine production and effects: I. In vivo regulatory networks involving the neuroendocrine system, interleukin-1 and tumor necrosis factor-alpha
    • Butler LD, Layman NK, Riedl PE et al. Neuroendocrine regulation of in vivo cytokine production and effects: I. In vivo regulatory networks involving the neuroendocrine system, interleukin-1 and tumor necrosis factor-alpha. J Neuroimmunol 1989; 24:143-53.
    • (1989) J Neuroimmunol , vol.24 , pp. 143-153
    • Butler, L.D.1    Layman, N.K.2    Riedl, P.E.3
  • 43
    • 0031040280 scopus 로고    scopus 로고
    • The role of adrenocorticoids as modulators of immune function in health and disease: Neural, endocrine and immune interactions
    • McEwen BS, Biron CA, Brunson KW et al. The role of adrenocorticoids as modulators of immune function in health and disease: neural, endocrine and immune interactions. Brain Res Rev 1997; 23:79-133.
    • (1997) Brain Res Rev , vol.23 , pp. 79-133
    • McEwen, B.S.1    Biron, C.A.2    Brunson, K.W.3
  • 44
    • 0023066651 scopus 로고
    • Intracellular receptor concentration limits glucocorticoid-dependent enhancer activity
    • Vanderbilt JN, Miesfield R, Maler BA, Yamamoto KR. Intracellular receptor concentration limits glucocorticoid-dependent enhancer activity. Mol Endocrinol 1987; 1:68-74.
    • (1987) Mol Endocrinol , vol.1 , pp. 68-74
    • Vanderbilt, J.N.1    Miesfield, R.2    Maler, B.A.3    Yamamoto, K.R.4
  • 45
    • 0027101803 scopus 로고
    • Lipopolysaccharide increases glucocorticoid receptor expression in murine macrophages. A posible mechanism for glucocorticoid-mediated suppression of endotoxicity
    • Salkowski AA, Vogel SN. Lipopolysaccharide increases glucocorticoid receptor expression in murine macrophages. A posible mechanism for glucocorticoid-mediated suppression of endotoxicity. J Immunol 1992; 149:4041-7.
    • (1992) J Immunol , vol.149 , pp. 4041-4047
    • Salkowski, A.A.1    Vogel, S.N.2
  • 46
    • 0021367753 scopus 로고
    • Down-regulation of glucocorticoid receptors in mouse lymphoma cell variants
    • Danielsen M, Stallcup MR. Down-regulation of glucocorticoid receptors in mouse lymphoma cell variants. Mol Cell Biol 1984; 4:449-53.
    • (1984) Mol Cell Biol , vol.4 , pp. 449-453
    • Danielsen, M.1    Stallcup, M.R.2
  • 47
    • 0032852382 scopus 로고    scopus 로고
    • Enhanced expression of integrins and CD66b on peripheral blood neutrophils and eosinophils in patients with rheumatoid arthritis, and the effects of glucocorticoids
    • Torsteinsdottir I, Arvidson NG, Hallgren R, Hakansson L. Enhanced expression of integrins and CD66b on peripheral blood neutrophils and eosinophils in patients with rheumatoid arthritis, and the effects of glucocorticoids. Scand J Immunol 1999; 50:433-9.
    • (1999) Scand J Immunol , vol.50 , pp. 433-439
    • Torsteinsdottir, I.1    Arvidson, N.G.2    Hallgren, R.3    Hakansson, L.4
  • 48
    • 0013085031 scopus 로고    scopus 로고
    • Glucocorticoid receptor regulates expression of L-selectin and CD11/CD18 on human neutrophils
    • Filep JG, Delalandre A, Payette Y, Foldes-Filep E. Glucocorticoid receptor regulates expression of L-selectin and CD11/CD18 on human neutrophils. Circulation 1997; 97:2279-81.
    • (1997) Circulation , vol.97 , pp. 2279-2281
    • Filep, J.G.1    Delalandre, A.2    Payette, Y.3    Foldes-Filep, E.4
  • 49
    • 0026470092 scopus 로고
    • A mechanism for the antiinflamatory effects of corticosteroids: The glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1
    • Cronstein BN, Kimmel SC, Levin RI, Martiniuk F, Weismann G. A mechanism for the antiinflamatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc Natl Acad Sci USA 1992; 89:9991-5.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9991-9995
    • Cronstein, B.N.1    Kimmel, S.C.2    Levin, R.I.3    Martiniuk, F.4    Weismann, G.5
  • 50
    • 0031805077 scopus 로고    scopus 로고
    • Endogenous glucocorticoids modulate neutrophil migration and synovial P-selectin but not neutrophil phagocytic or oxidative function in experimental arthritis
    • Leech M, Hutchinson P, Holsworth SR, Morand EF. Endogenous glucocorticoids modulate neutrophil migration and synovial P-selectin but not neutrophil phagocytic or oxidative function in experimental arthritis. Clin Exp Immunol 1998; 112:383-8.
    • (1998) Clin Exp Immunol , vol.112 , pp. 383-388
    • Leech, M.1    Hutchinson, P.2    Holsworth, S.R.3    Morand, E.F.4
  • 51
    • 0030043899 scopus 로고    scopus 로고
    • Immune-neuro-endocrine interaction: Facts and hypotheses
    • Besedovsky HO, Del Rey A. Immune-neuro-endocrine interaction: facts and hypotheses. Endocr Rev 1996; 17:64-102.
    • (1996) Endocr Rev , vol.17 , pp. 64-102
    • Besedovsky, H.O.1    Del Rey, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.