Effects of Gamichunggantang on hyperlipidemia

Acta Pharmacologica Sinica

Volumn 24, Issue 2, 2003, Pages 133-139

  Son, Chang Gue ^a   Choi, Woo Jin ^a   Shin, Jang Woo ^a   Han, Seung Hyun ^b   Cho, Jung Hyo ^a   Song, Kee Cheol ^a   Cho, Chong Kwan ^c  

^a Daejeon University   (South Korea)

^b University of Seoul   (South Korea)

^c NONE

Author keywords

Cholesterol; Hyperlipidemia; O acyltransferase; Triglycerides

Indexed keywords

CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; DIACYLGLYCEROL ACYLTRANSFERASE; GAMICHUNGGANTANG; HERBACEOUS AGENT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALCOHOL LIVER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DIETARY INTAKE; DRUG ABSORPTION; DRUG ACTIVITY; DRUG EFFICACY; FATTY LIVER; GENE EXPRESSION; HERBAL MEDICINE; HISTOPATHOLOGY; HYPERLIPIDEMIA; INTESTINE ABSORPTION; LIPID METABOLISM; LIVER WEIGHT; MALE; NONHUMAN; RAT;

ACYLTRANSFERASES; ANIMALS; ANTILIPEMIC AGENTS; ARTEMISIA; DIACYLGLYCEROL O-ACYLTRANSFERASE; DRUG COMBINATIONS; DRUGS, CHINESE HERBAL; HYPERLIPIDEMIAS; LIVER; MALE; ORGAN SIZE; PLANTS, MEDICINAL; POLYPORALES; RATS; RATS, SPRAGUE-DAWLEY; STEROL O-ACYLTRANSFERASE;

EID: 0037309591     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Turpeinen O. Effect of cholesterol-lowering diet on mortality from coronary heart disease and other causes. Circulation 1979; 59: 1-7.
2. Gibbons GF, Mitropoulos KA, Myant NB. Biochemistry of cholesterol. Amsterdam: Elsevier; 1982. p 369.
3. Bloth K. Biological synthesis of cholesterol. In: The Harvey Lectures; v 48. New York: Academic Press; 1954. p 68-88.
4. Bloth K. The biological synthesis of cholesterol. Science 1965; 150: 19-28.
5. Frick MH, Elo O, Haapa K, Heinonen OP, Heinsalmi P, Helo P, et al. Helsinki heart study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 1987; 317: 1237-45.
6. Bhatnagar D. Lipid-lowering drugs n the management of hyperlipidaemeia. Pharmacol Ther 1998; 79: 205-3.
7. Ghasi S, Nwobodo E, Ofili JO. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed Wistar rats. J Ethnopharmacol 2000; 69: 21-5.
8. Gupta RS, Kumar P, Sharma A, Bharadwaj TN, Dixit VP. Hypocholesterolemic activity of Marsilea minuta in gerbils. Fitoterapia 2000; 71: 113-7.
9. Gardner CD, Chaterjee LM, Carlson JJ. The effect of a garlic preparation on plasma lipid levels in moderately hypercholesterolemic adults. Atherosclerosis 2001; 154: 213-20.
10. Saleh J, Sniderman AD, Cianflone K. Regulation of plasma fatty acid metabolism. Clin Chim Acta 1999; 286: 163-80.
11. Sniderman AD, Cianflone K. Lipid and vascular disease: what do and do not know. Clin Chim Acta 1999; 286: 7-22.
12. Brites FD, Bonavita CD, Cloës M, Yael MJ, Fruchart JC, Castro GR, et al. LDL compositional changes and plasma levels of triglycerides and high density lipoprotein. Clin Chim Acta 1998; 269: 7-124.
13. Liscum L, Munn NJ. Intracellular cholesterol transport. Biochim Biophys Acta 1999; 1438: 19-37.
14. She M, Wang Z. The protective role of high-density lipoproteins in atherosclerosis. Exper Gerontol 1999; 34: 539-48.
15. Hesser JR, Robertson AL, Chisolm GM. LDL-induced cytotoxicity and its inhibition by HDL in human vascular smooth muscle and endothelial cells in culture. Atherosclerosis 1979; 32: 213-29.
16. Mackness MI, Durrington PN. HDL, its enzymes and its potential to influence lipid peroxidation. Atherosclerosis 1995; 115:243-53.
17. Hobbs DH, Lu C, Hills MJ. Cloning of a cDNA encoding diacylglycerol acyltransferase from Arabidopsis thaliana and its functional expression 1999; 452:145-9.
18. Dircks L, Sul HS. Acyltransferases of de novo glycero-phospholipid biosynthesis. Prog Lipid Res 1999; 38: 461-79.
19. Katsuren K, Tamura T, Arashiro R, Takata K, Matsuura T, Niikawa N, et al. Structure of the human acyl-CoA:cholesterol acyltransferase-2 (ACAT-2) gene and its relation to dyslipidemia. Biochim Biophys Acta 2001; 1531: 230-40.
20. Son CG, Choi BL, Shin JW, Choi WJ, Cho JH, Cho CK. Effects of gamichunggantang (GCT) on alcohol metabolism and alcoholic liver disease. Korean J Orient Med 2001; 2: 89-98.
21. Yamamoto M, Ogawa K, Morita M, Fukuda K, Komatsu Y. The herbal medicine Inchin-ko-to inhibits liver cell apoptosis induced by transforming growth factor beta 1. Hepatology 1996; 23: 552-9.
22. Kim YC, Kim JJ, Lee JH, Woo HJ. Effects of injinchunggantang on fulminant mouse viral hepatitis. J Orient Med 1996; 1: 32-47.
23. Lee GM, Jeon BH, Kim WS, Sung LG. The effects of the water extract of gagaminjinhotang on the liver damage induced by bile duct ligation. Korean J Orient Med Pathol 1993; 8: 71-110.
24. Xiong LL. Therapeutic effect of combined therapy of Salvia miltiorrhizae and Polyporus umbellatus polysaccharide in the treatment of chronic hepatitis B. Chin J Integrated Tradit West Med 1993; 13: 533-5, 516-7.
25. Lin YF, Wu GL. Protective effect of Polyporus umbellatus polysaccharide on toxic hepatitis in mice. Acta Pharmacol Sin 1988; 9: 345-8.