Inhibition of vascular ATP-sensitive K+ channels does not affect reactive hyperemia in human forearm

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 284, Issue 2 53-2, 2003, Pages

  Farouque, H M Omar ^a   Meredith, Ian T ^a,b  

^a MONASH UNIVERSITY   (Australia)

^b MONASH MEDICAL CENTRE   (Australia)

Author keywords

Ion channels; Ischemia; Regional blood flow

Indexed keywords

ADENOSINE TRIPHOSPHATE; DIAZOXIDE; GLIBENCLAMIDE; GLIMEPIRIDE; NICORANDIL; POTASSIUM CHANNEL; SULFONYLUREA DERIVATIVE;

ADULT; ARM BLOOD FLOW; ARTICLE; BRACHIAL ARTERY; CONTROLLED STUDY; FEMALE; FOREARM; HUMAN; HUMAN EXPERIMENT; HYPEREMIA; ISCHEMIA; MALE; NORMAL HUMAN; PRIORITY JOURNAL; VEIN OCCLUSION PLETHYSMOGRAPHY;

EID: 0037307491     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00315.2002     Document Type: Article

References (52)

1. Aversano T, Ouyang P, and Silverman H. Blockade of the ATP-sensitive potassium channel modulates reactive hyperemia in the canine coronary circulation. Circ Res 69: 618-622, 1991.
2. Banitt PF, Smits P, Williams SB, Ganz P, and Creager MA. Activation of ATP-sensitive potassium channels contributes to reactive hyperemia in humans. Am J Physiol Heart Circ Physiol 271: H1594-H1598, 1996.
3. Bank AJ, Sih R, Mullen K, Osayamwen M, and Lee PC. Vascular ATP-dependent potassium channels, nitric oxide, and human forearm reactive hyperemia. Cardiovasc Drugs Ther 14: 23-29, 2000.
4. + channel function in cerebral arterioles in piglets. Stroke 27: 1874-1880, 1996.
5. Baron AD. Hemodynamic actions of insulin. Am J Physiol Endocrinol Metab 267: E187-E202, 1994.
6. Bayliss WM. On the local reactions of the arterial wall to changes of internal pressure. J Physiol 28: 220-231, 1902.
7. Bijlstra PJ, den Arend JA, Lutterman JA, Russel FG, Thien T, and Smits P. Blockade of vascular ATP-sensitive potassium channels reduces the vasodilator response to ischaemia in humans. Diabetologia 39: 1562-1568, 1996.
8. Bijlstra PJ, Lutterman JA, Russel FG, Thien T, and Smits P. Interaction of sulphonylurea derivatives with vascular ATP-sensitive potassium channels in humans. Diabetologia 39: 1083-1090, 1996.
9. Binzoni T, Quaresima V, Barattelli G, Hiltbrand E, Gurke L, Terrier F, Cerretelli P, and Ferrari M. Energy metabolism and interstitial fluid displacement in human gastrocnemius during short ischemic cycles. J Appl Physiol 85: 1244-1251, 1998.
10. Carlsson I, Sollevi A, and Wennmalm A. The role of myogenic relaxation, adenosine and prostaglandins in human forearm reactive hyperaemia. J Physiol 389: 147-161, 1987.
11. Coppack SW, Lant AF, McIntosh CS, and Rodgers AV. Pharmacokinetic and pharmacodynamic studies of glibenclamide in non-insulin dependent diabetes mellitus. Br J Clin Pharmacol 29: 673-684, 1990.
12. Dakak N, Husain S, Mulcahy D, Andrews NP, Panza JA, Waclawiw M, Schenke W, and Quyyumi AA. Contribution of nitric oxide to reactive hyperemia: impact of endothelial dysfunction. Hypertension 32: 9-15, 1998.
13. Daut J, Maier-Rudolph W, von Beckerath N, Mehrke G, Gunther K, and Goedel-Meinen L. Hypoxic dilation of coronary arteries is mediated by ATP-sensitive potassium channels. Science 247: 1341-1344, 1990.
14. Dhein S, Pejman P, and Krusemann K. Effects of the I(K.ATP) blockers glibenclamide and HMR1883 on cardiac electrophysiology during ischemia and reperfusion. Eur J Pharmacol 398: 273-284, 2000.
15. Duffy SJ, New G, Tran BT, Harper RW, and Meredith IT. Relative contribution of vasodilator prostanoids and NO to metabolic vasodilation in the human forearm. Am J Physiol Heart Circ Physiol 276: H663-H670, 1999.
16. + ATP channels in coronary vasodilation during exercise. Circulation 88: 1245-1253, 1993.
17. Engelke KA, Halliwill JR, Proctor DN, Dietz NM, and Joyner MJ. Contribution of nitric oxide and prostaglandins to reactive hyperemia in human forearm. J Appl Physiol 81: 1807-1814, 1996.
18. Faraci FM and Heistad DD. Role of ATP-sensitive potassium channels in the basilar artery. Am J Physiol Heart Circ Physiol 264: H8-H13, 1993.
19. Farouque HMO and Meredith IT. Effects of inhibition of ATP-sensitive potassium channels on metabolic vasodilation in the human forearm. Clin Sci. In press.
20. Farouque HMO, Worthley SG, Meredith IT, Skyrme-Jones RA, and Zhang MJ. Effect of ATP-sensitive potassium channel inhibition on resting coronary vascular responses in humans. Circ Res 90: 231-236, 2002.
21. Farouque HMO, Worthley SG, Zhang MJ, Baldi MA, and Meredith IT. The contribution of ATP-sensitive potassium channels to metabolic coronary vasodilation in the human (Abstract). Circulation 104, Suppl: II-151, 2001.
22. + currents in human coronary artery vascular smooth muscle cells. Circ Res 78: 676-688, 1996.
23. Hoffinan RP, Sinkey CA, and Tsalikian E. Effect of local sympathetic blockade on forearm blood flow and glucose uptake during hypoglycemia. Metabolism 48: 1575-1583, 1999.
24. Hongo M, Takenaka H, Uchikawa S, Nakatsuka T, Watanabe N, and Sekiguchi M. Coronary microvascular response to intracoronary administration of nicorandil. Am J Cardiol 75: 246-250, 1995.
25. + channels on afferent arteriolar diameter in diabetes mellitus. J Am Soc Nephrol 11: 1199-1207, 2000.
26. Imamura Y, Tomoike H, Narishige T, Takahashi T, Kasuya H, and Takeshita A. Glibenclamide decreases basal coronary blood flow in anesthetized dogs. Am J Physiol Heart Circ Physiol 263: H399-H404, 1992.
27. + channels, adenosine, and nitric oxide-mediated mechanisms account for coronary vasodilation during exercise. Circ Res 82: 346-359, 1998.
28. Jackson WF, Konig A, Dambacher T, and Busse R. Prostacyclin-induced vasodilation in rabbit heart is mediated by ATP-sensitive potassium channels. Am J Physiol Heart Circ Physiol 264: H238-H243, 1993.
29. Kilbom A and Wenrimalm A. Endogenous prostaglandins as local regulators of blood flow in man: effect of indomethacin on reactive and functional hyperaemia. J Physiol 257: 109-121, 1976.
30. Kosmas EN, Levy RD, and Hussain SN. Acute effects of glyburide on the regulation of peripheral blood flow in normal humans. Eur J Pharmacol 274: 193-199, 1995.
31. Larkin SW and Williams TJ. Evidence for sensory nerve involvement in cutaneous reactive hyperemia in humans. Circ Res 73: 147-154, 1993.
32. Lee SW, Wang HZ, and Christ GJ. Characterization of ATP-sensitive potassium channels in human corporal smooth muscle cells. Int J Impot Res 11: 179-188, 1999.
33. Loscalzo J and Vita JA. Ischemia, hyperemia, exercise, and nitric oxide. Complex physiology and complex molecular adaptations. Circulation 90: 2556-2559, 1994.
34. Matthews JNS, Altman DG, Campbell MJ, and Royston P. Analysis of serial measurements in medical research. BMJ 300: 230-235, 1990.
35. McKay MK and Hester RL. Role of nitric oxide, adenosine, and ATP-sensitive potassium channels in insulin-induced vasodilation. Hypertension 28: 202-208, 1996.
36. + channel openers. J Vasc Res 30: 2-12, 1993.
37. + channel-dependent as well as independent components of pinacidil-induced vasodilation. J Pharmacol Exp Ther 256: 492-499, 1991.
38. Meredith IT, Currie KE, Anderson TJ, Roddy MA, Ganz P, and Creager MA. Postischemic vasodilation in human forearm is dependent on endothelium-derived nitric oxide. Am J Physiol Heart Circ Physiol 270: H1435-H1440, 1996.
39. Nelson MT and Quayle JM. Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol Cell Physiol 268: C799-C822, 1995.
40. + channels regulates coronary blood flow in ischemic myocardium. Circulation 95: 1560-1567, 1997.
41. Patterson CG and Whelan RF. Reactive hyperaemia in the human forearm. Clin Sci 14: 197-209, 1955.
42. + channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide. J Pharmacol Exp Ther 250: 261-271, 1989.
43. + currents in smooth muscle cells from rabbit mesenteric artery. Am J Physiol Cell Physiol 269: C1112-C1118, 1995.
44. Reimann F, Ashcroft FM, and Gribble FM. Structural basis for the interference between nicorandil and sulfonylurea action. Diabetes 50: 2253-2259, 2001.
45. Reslerova M and Loutzenhiser R. Renal microvascular actions of calcitonin gene-related peptide. Am J Physiol Renal Physiol 274: F1078-F1085, 1998.
46. Rusch NJ, Shepherd JT, Webb RC, and Vanhoutte PM. Different behavior of the resistance vessels of the human calf and forearm during contralateral isometric exercise, mental stress, and abnormal respiratory movements. Circ Res 48: I118-I130, 1981.
47. Saito Y, McKay M, Eraslan A, and Hester RL. Functional hyperemia in striated muscle is reduced following blockade of ATP-sensitive potassium channels. Am J Physiol Heart Circ Physiol 270: H1649-H1654, 1996.
48. Samaha FF, Heineman FW, Ince C, Fleming J, and Balaban RS. ATP-sensitive potassium channel is essential to maintain basal coronary vascular tone in vivo. Am J Physiol Cell Physiol 262: C1220-C1227, 1992.
49. + channels in arterial smooth muscle. Science 245: 177-180, 1989.
50. Suryapranata H. Coronary haemodynamics and vasodilatory profile of a potassium channel opener in patients with coronary artery disease. Eur Heart J 14, Suppl B: 16-21, 1993.
51. a. The IONA Study Group. Effect of nicorandil on coronary events in patients with stable angina: the Impact Of Nicorandil in Angina (IONA) randomised trial. Lancet 359: 1269-1275, 2002.
52. Vanelli G and Hussain SN. Effects of potassium channel blockers on basal vascular tone and reactive hyperemia of canine diaphragm. Am J Physiol Heart Circ Physiol 266: H43-H51, 1994.