The novel serine protease PreR-Co promotes endothelium-independent vasorelaxation in rabbit aortic rings

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 284, Issue 2 53-2, 2003, Pages

  De Bruno, María Peral ^a   Vincent, Paula A ^b   Romano, Liliana ^a   Guardia, D Cecilia ^b   Coviello, Alfredo ^b   De Vito, Eduardo ^b  

^a Universidad Nacional de Tucuman UNT Facultad de Medicina   (Argentina)

^b UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

Author keywords

Rabbit aorta; Renin activators; Vasorelaxant activity

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN; APROTININ; BRADYKININ; ENALAPRILAT; ICATIBANT; INDOMETACIN; KALLIKREIN; LOSARTAN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NORADRENALIN; POTASSIUM CHLORIDE; PRER CO SERINE PROTEINASE; PRORENIN; PROSTAGLANDIN; PROSTAGLANDIN F2 ALPHA; SERINE PROTEINASE; SOYBEAN TRYPSIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; ENDOTHELIUM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; VASCULAR RING; VASODILATATION;

EID: 0037306698     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.0792.2001     Document Type: Article

References (35)

1. Brosnihan KB, Li P, Tallant EA, and Ferrario CM. Angiotensin-(1-7): a novel vasodilator of the coronary circulation. Biol Res 31: 227-234, 1998.
2. Campbell WB, Gebremedhin D, Pratt PF, and Harder DR. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ Res 78: 415-423, 1996.
3. Chen S, Patel JM, and Block ER. Angiotensin IV-mediated pulmonary artery vasorelaxation is due to endothelial intracellular calcium release. Am J Physiol Lung Cell Mol Physiol 279: L849-L856, 2000.
4. Cheng DY, De Witt BJ, Dent EL, Nossaman BD, and Kadowitz PJ. Analysis of responses to angiotensin IV in the pulmonary vascular bed of the cat. Eur J Pharmacol 261: 223-227, 1994.
5. + channel genes in arteries from spontaneously hypertensive and Wistar-Kyoto rats. Hypertension 37: 1315-1322, 2001.
6. De Vito E, Cabrera RR, and Fasciolo JC. Renin production and release by rat kidney slices. Am J Physiol 219: 1042-1045, 1970.
7. De Vito E, Guardia DC, and Martinez de Melián ER. Activation of inactive renal renin by nephrectomized and non-nephrectomized rat plasma. A novel enzymatic mechanism of renin activation? Comp Biochem Physiol 113B: 433-438, 1996.
8. Engler MB, Engler MM, Browne A, Sun YP, and Sievers R. Mechanisms of vasorelaxation induced by eicosapentaenoic acid (20:5n-3) in WKY aorta. Br J Pharmacol 131: 1793-1799, 2000.
9. Feterik K, Smith L, and Katusic ZS. Angiotensin-(1-7) causes endothelium-dependent relaxation in canine middle cerebral artery. Brain Res 873: 75-82, 2000.
10. Forstermann U, Herting G, and Neufang B. The importance of endogenous prostaglandins other than prostacyclin for the modulation of contractility of some rabbit blood vessels. Br J Pharmacol 81: 623-630, 1984.
11. Furchgott RF and Zawadski JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373-376, 1980.
12. Gohlke P, Bunning P, and Unger T. Distribution and metabolism of angiotensin I and II in the blood vessel wall. Hypertension 20: 151-157, 1992.
13. 2. Eur J Pharmacol 98: 323-330, 1984.
14. Khalidi N, McKenzie I, and McKenzie JK. Isoelectric heterogeneity of human prorenin (inactive renin) in body fluids. Am J Hypertens 4: 56-59, 1999.
15. Kuziema-Leska M, Car H, and Wisniewski K. Effect of bicuculline and angiotensin II fragment 3-7 on learning and memory processes in rats chronically treated with ethanol. Pol J Pharmacol 50: 15-22, 1998.
16. Li PL, Zou AP, and Campbell WB. Regulation of potassium channels in coronary arterial smooth muscle by endotheliumderived vasodilator. Hypertension 29: 262-267, 1997.
17. Lilly LS, Pratt RE, Alexander RW, Larson DM, Ellison KE, Gimbrone MA Jr, and Dzau VJ. Renin expression by vascular endothelial cells in culture. Circ Res 57: 312-318, 1985.
18. Lin L and Nasjletti A. Role of endothelium-derived prostanoids in angiotensin-induced vasoconstriction. Hypertension 18: 158-164, 1991.
19. Linz W, Wiemer G, Gohlke P, Unger T, and Scholkens BA. Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors. Pharmacol Rev 47: 25-49, 1995.
20. Lüscher TF. Imbalance of endothelium-derived relaxing and contracting factors. Am J Hypertens 3: 317-330, 1990.
21. Mahon JM, Carr RD, Nicol AK, and Henderson IW. Angiotensin-(1-7) is an antagonist at the type 1 angiotensin II receptor. J Hypertens 12: 1377-1381, 1994.
22. Mizuno K, Tani M, Niimura S, Hashimoto S, Satoh A, Shimamoto K, Inagami T, and Fucuchi S. Direct evidence for local generation and release of angiotensin II in human vascular tissue. Biochem Biophys Res Commun 165: 457-463, 1989.
23. Peral de Bruno M, Coviello A, Meyer M, and Forssmann WG. Relaxation of non-contracted smooth muscle by atrial natriuretic peptide. Clin Exp Hypertens 14: 1125-1139, 1992.
24. Peral de Bruno M, Romano L, and Coviello A. Losartan reduces the vasorelaxant effect of atrial natriuretic peptide on basal tone in aorta. Clin Exp Hypertens 21: 1257-1271, 1999.
25. Peral de Bruno M, Romano L, Proto M, and Coviello A. Atrial natriuretic peptide relaxes arterial basal tone induced by coarctation hypertension. Peptides 20: 485-491, 1999.
26. Pfister SL, Spitzbarth N, Nithipatikom K, Edgemond WS, Falck JR, and Campbell WB. Identification of the 11,14,15-and 11,12,15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta. J Biol Chem 273: 3879-3887, 1998.
27. Phillips MI, Speakman EA, and Kimura B. Levels of angiotensin and molecular biology of the tissue renin angiotensin systems. Regul Pept 42: 1-20, 1993.
28. Pucci ML, Miller KB, Dick LB, Guan H, Lin L, and Nasjletti A. Vascular responsiveness to nitric oxide synthesis inhibition in hypertensive rats. Hypertension 23: 744-751, 1994.
29. Regoli D, Mizrahi J, D'Orleans-Juste P, and Caranikas S. Effects of kinins on isolated blood vessels. Role of endothelium. Can J Physiol Pharmacol 60:1580-1583, 1982.
30. 2 receptor antagonist [HOE 140: D-Arg(Hyp3, Thi5, D-Tic7, Qic8)bradykinin]. Eur J Pharmacol 210: 115-120, 1992.
31. Rosenthal JH, Pfeifle B, Michailov ML, Pschorr J, Jacob IC, and Dahlheim H. Investigations of components of the renin-angiotensin system in rat vascular tissue. Hypertension 6: 383-390, 1984.
32. Siegel G, Walter A, Schnalke F, Schmidt Buddecke E, Loirand G, and Stock G. Potassium channel activation, hyperpolarization, and vascular relaxation. Z Kardiol 80, Suppl 7: 9-24, 1991.
33. : Vincent PA, Adler C, Avila C, Guardia DC, and De Vito E. Prorenins activation by an enzyme from rat plasma (PreR-Co). Comp Biochem Physiol B Biochem Mol Biol 131: 201-207, 2002.
34. Vincent PA and De Vito E. Rat renal and plasma prorenin are activated in vitro by different mechanisms. Hypertension 34: 520-524, 1999.
35. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, and Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332: 411-415, 1988.