Dose dependence of the growth rate of multicellular tumour spheroids after irradiation

British Journal of Radiology

Volumn 76, Issue 902, 2003, Pages 109-116

  Guirado, D ^b   Aranda, M ^b   Vilches, M ^a   Villalobos, M ^b   Lallena, A M ^b  

^a HOSPITAL UNIVERSITARIO SAN CECILIO   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL POPULATION; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL SURVIVAL; CLONOGENIC ASSAY; CONTROLLED STUDY; DOSE RESPONSE; DOSIMETRY; EXPERIMENTAL MODEL; HUMAN; HUMAN CELL; IRRADIATION; RADIATION DOSE FRACTIONATION; SPHEROID CELL; TUMOR GROWTH; TUMOR SPHEROID; TUMOR VOLUME;

BREAST NEOPLASMS; CELL DIVISION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; TUMOR CELLS, CULTURED;

EID: 0037306562     PISSN: 00071285     EISSN: None     Source Type: Journal    
DOI: 10.1259/bjr/30772617     Document Type: Article

References (29)

1. Sutherland RM. Cell and environment interactions in tumour microregions: The multicell spheroid model. Science 1988;240:177-84.
2. Santini RT, Rainaldi G, Indovina PL. Multicellular tumour spheroids in radiation biology. Int J Radiat Biol 1999;75:787-99.
3. Durand R, Olive PL. Resistance of tumour cells to chemo and radiotherapy modulated by the three-dimensional architecture of solid tumours and spheroids. Method Cell Biol 2001;64:211-29.
4. Fertil B, Malaise EP. Inherent cellular radiosensitivity as a basic concept for human tumour radiosensitivity. Int J Radiat Oncol Biol Phys 1981;7:621-9.
5. Deacon J, Peckham MJ, Steell GG. The radioresponsiveness of human tumours and the initial slope of the cell survival curve. Radiother Oncol 1984;2:317-23.
6. Buffa FM, Davidson SE, Hunter RD, Nahum AE, West CML. Incorporating biologic measurements (SF2,CFE) into tumour control probability model increases their prognostic significance: A study in cervical carcinoma treated with radiotherapy. Int J Radiat Oncol Biol Phys 2001;50:1113-22.
7. Weichselbaum RR, Little JB, Tomkison K, et al. Repair of fractionated radiation in plateau phase cultures of human tumour cells and human multicellular tumour spheroids. Radiother Oncol 1984;2:41-7.
8. Hill SA, Denekamp J. An experimental study of tumour size and radiosensitivity: Analysis of regrowth delay. Radiother Oncol 1989;15:39-48.
9. Schwachöfer JHM, Crooijmans RPMA, Van Gasteren JJM, et al. Repair of sublethal damage in two human tumour cell lines grown as multicellular spheroids. Int J Radiat Oncol Biol Phys 1989;17:591-5.
10. Schwachöfer JHM, Crooijmans RPMA, Hoogenhout J, et al. Radiosensitivity of human melanoma spheroids influenced by growth rate. Int J Radiat Oncol Biol Phys 1990;19:1191-7.
11. Wheldon TE, Livingstone A, Wilson L, et al. The radiosensitivity of human neuroblastoma cells estimated from regrowth curves of multicellular tumour spheroids. Br J Radiol 1985;58:661-4.
12. Soule HD, Vázquez J, Long A, et al. A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer 1973;51:1409-16.
13. Olea N, Villalobos M, Ruiz De Almodóvar JM, et al. MCF-7 breast cancer cells grown as multicelllular spheroids in vitro: Effect of 17β-estradiol. Int J Cancer 1992;50:112-7.
14. Olea N, Villalobos M, Núñez MI, et al. Evaluation of the growth rate of MCF-7 breast cancer multicellular spheroids using three mathematical models. Cell Prolif 1994;27:213-23.
15. Schwachöfer JHM, Crooijmans RPMA, Van Gasteren JJM, et al. Radiosensitivity of different human tumour cell lines grown as multicellular sphéroids determined from growth curves and survival data. Int J Radiat Oncol Biol Phys 1989;17:1015-20.
16. Gompertz B. On the nature of the function expressive of the law of human mortality and on a new model of determining life contingencies. Philos Trans R Soc 1825;115:513-85.
17. Wright S. Book review. J Am Stat Assoc 1926;21:494.
18. Winsor CP. The Gompertz curve as a growth curve. Proc Natl Acad Sci 1932;18:1-8.
19. Laird AK. The dynamics of tumour growth. Br J Cancer 1964;28:490-502.
20. Rofstad EK, Wahl A, Brustad T. Radiation response of human melanoma multicellular spheroids measured as single cell survival growth delay and spheroids cure: Comparisons with the parent tumour xenograft. Int J Radiat Oncol Biol Phys 1986;12:975-82.
21. Villalobos M, Aranda M, Núñez MI, et al. Interaction between ionizing radiation estrogens and antiestrogens in the modification of tumour microenvironment in estrogen dependent multicellular spheroids. Acta Oncol 1995;34:413-7.
22. O'Donoghue JA. The response of tumours with Gompertzian growth characteristics to fractionated radiotherapy. Int J Radiat Biol 1997;72:325-39.
23. Villalobos M. Modelos tumorales en oncología: Los esferoides multicelulares en el estudio del cáncer hormodependiente. PhD thesis. Granada, Spain: Universidad de Granada, 1990. (In Spanish.)
24. International Organization for standardization/TAG 4 Work Group 3. Guide to the Expressions of Uncertainties in Measurements. Geneva, Switzerland: ISO, 1992.
25. Press WH, Teukolsky SA, Vetterling WT, et al. Numerical Recipes in Fortran. The Art of Scientific Computing (2nd edn). New York, NY: Cambridge University Press, 1995:678-83.
26. Chadwick KH, Leenhouts HP, editors. A Molecular Theory of Radiation Biology. Berlin, Germany: Springer-Verlag, 1981.
27. Hawkins RB. Survival of a mixture of cells of variable linear-quadratic sensitivity to radiation. Radiat Res 2000;153:840-3.
28. Núñez MI, Villalobos M, Olea N, et al. Radiation-induced DNA double-strand break rejoining in human tumour cells. Br J Cancer 1995;71:311-6.
29. Olive PL, Durand RE. Drug and radiation resistance in spheroids: Cell contact and kinetics. Cancer Metast Rev 1994;13:121-38.