Outcomes of hyaluronan therapy in diabetic foot wounds

Diabetes Research and Clinical Practice

Volumn 59, Issue 2, 2003, Pages 123-127

  Vazquez, J R ^a   Short, Brian ^a   Findlow, Andrew H ^b   Nixon, Brent P ^a   Boulton, Andrew J M ^b   Armstrong, David G ^a,b  

^a 2 112 Tucson   (United States)

^b MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Amputation; Diabetes; Foot; Ulcer; Wound

Indexed keywords

HEMOGLOBIN A1C; HYALURONIC ACID;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DEBRIDEMENT; DIABETES MELLITUS; DIABETIC FOOT; DISEASE COURSE; EPITHELIZATION; FEMALE; HUMAN; MALE; OUTCOMES RESEARCH; SKIN EPITHELIUM; WOUND CLOSURE; WOUND DRESSING; WOUND HEALING;

ADJUVANTS, IMMUNOLOGIC; DEBRIDEMENT; DIABETIC FOOT; FEMALE; HUMANS; HYALURONIC ACID; MALE; MIDDLE AGED; OCCLUSIVE DRESSINGS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; WOUND HEALING;

EID: 0037304927     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8227(02)00197-3     Document Type: Article

References (26)

1. Pecoraro R.E., Reiber G.E., Burgess E.M. Pathways to diabetic limb amputation: basis for prevention. Diabetes Care. 13:1990;513-521.
2. Armstrong D.G. Is diabetic foot care efficacious or cost-effective. Ostomy Wound Manage. 47:2001;28-32.
3. Chen J.W.Y., Abatangelo G. Functions of hyaluronan in wound repair. Wound Repair Regen. 7:1999;79-89.
4. Kvam B.J., Fragonas E., Degrassi A., et al. Oxygen-derived free radical (ODFR) action on hyaluronan (HA), on two HA ester derivatives, and on the metabolism of articular chondrocytes. Exp. Cell Res. 218:(1):1995;79-86.
5. Benedetti L., Cortivo R., Berti T., et al. Biocompatibility and biodegradation of different hyaluronan derivatives (Hyaff) implanted in rats. Biomaterials. 14:(15):1993;1154-1160.
6. Abatangelo G., Martelli M., Vecchia P. Healing of hyaluronic acid-enriched wounds: histological observations. J. Surg. Res. 35:(5):1983;410-416.
7. Nakamura M., Sato N., Chikama T.I., Hasegawa Y., Nishida T. Hyaluronan facilitates corneal epithelial wound healing in diabetic rats. Exp. Eye Res. 64:(6):1997;1043-1050.
8. Longaker M.T., Chiu E.S., Adzick N.S., Stern M., Harrison M.R., Stern R. Studies in fetal wound healing. V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid. Ann. Surg. 213:(4):1991;292-296.
9. Abatangelo G., Barbucci R., Brun P., Lamponi S. Biocompatibility and enzymatic degradation studies on sulphated hyaluronic acid derivatives. Biomaterials. 18:(21):1997;1411-1415.
10. Abatangelo G. Hyaluronic acid delays or impedes reepithelialization. J. Burn Care Rehabil. 18:(6):1997;552.
11. Greco R.M., Iocono J.A., Ehrlich H.P. Hyaluronic acid stimulates human fibroblast proliferation within a collagen matrix. J. Cell. Physiol. 177:(3):1998;465-473.
12. K. Ballard, H. Baxter, Developments in wound care for difficult to manage wounds, Br. J. Nurs. 9 (7) (2000) 405-408, 410-412.
13. Hehenberger K., Kratz G., Hansson A., Brismar K. Fibroblasts derived from human chronic diabetic wounds have a decreased proliferation rate, which is recovered by the addition of heparin. J. Dermatol. Sci. 16:(2):1998;144-151.
14. Armstrong D.G., Lavery L.A., Vela S.A., Quebedeaux T.L., Fleischli J.G. Choosing a practical screening instrument to identify patients at risk for diabetic foot ulceration. Arch. Internal Med. 158:1998;289-292.
15. Armstrong D.G., Athanasiou K.A. The edge effect: how and why wounds grow in size and depth. Clin. Podiatr. Med. Surg. 15:1998;105-108.
16. Armstrong D.G., Lavery L.A., Harkless L.B. Validation of a diabetic wound classification system: the contribution of depth, infection, and vascular disease to the risk of amputation. Diabetes Care. 21:1998;855-859.
17. Kirkwood B.R. Essentials of Medical Statistics. 1988;Blackwell, Oxford.
18. Mekkes J.R., Nahuys M. Induction of granulation tissue in chronic wounds by hyaluronic acid. Wounds. 13:(4):2001;159-164.
19. Iocono J.A., Krummel T.M., Keefer K.A., Allison G.M., Paul H. Repeated additions of hyaluronan alters granulation tissue deposition in sponge implants in mice. Wound Repair Regen. 6:(5):1998;442-448.
20. Iocono J.A., Ehrlich H.P., Keefer K.A., Krummel T.M. Hyaluronan induces scarless repair in mouse limb organ culture. J. Pediatr. Surg. 33:(4):1998;564-567.
21. Foster A.M., Bates M., Doxford M., Edmonds M.E. Treatment of indolent neuropathic ulceration of the diabetic foot with hyaff, an ester of hyaluronic acid. Diabetologia. 42:(Suppl. 1):1999;A29.
22. Sykes M.T., Godsey J.B. Vascular evaluation of the problem diabetic foot. Clin. Podiatr. Med. Surg. 15:(1):1998;49-83.
23. Lipsky B.A. Diabetic foot infections. Pathophysiology, diagnosis, and treatment. Int. J. Dermatol. 30:(8):1991;560-562.
24. Armstrong D.G., Nguyen H.C., Lavery L.A., van Schie C.H., Boulton A.J.M., Harkless L.B. Offloading the diabetic foot wound: a randomized clinical trial. Diabetes Care. 24:2001;1019-1022.
25. Armstrong D.G., Short B., Nixon B.P., Boulton A.J.M. Technique for fabrication of an 'instant' total contact cast for treatment of neuropathic diabetic foot ulcers. J. Am. Podiatr. Med. Assoc. 92:2002;405-408.
26. Armstrong D.G., Lavery L.A., Vazquez J.R., Nixon B.P., Boulton A.J.M. How and why to surgically debride diabetic foot wounds. J. Am. Podiatr. Med. Assoc. 92:2002;402-404.